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Items: 1 to 20 of 117

1.

Functional genomic and high-content screening for target discovery and deconvolution.

Heynen-Genel S, Pache L, Chanda SK, Rosen J.

Expert Opin Drug Discov. 2012 Oct;7(10):955-68. Epub 2012 Aug 4. Review.

2.

Recent advances in quantitative high throughput and high content data analysis.

Moutsatsos IK, Parker CN.

Expert Opin Drug Discov. 2016;11(4):415-23. doi: 10.1517/17460441.2016.1154036. Epub 2016 Mar 9. Review.

PMID:
26924521
3.

Screening methods for influenza antiviral drug discovery.

Atkins C, Evans CW, White EL, Noah JW.

Expert Opin Drug Discov. 2012 May;7(5):429-38. doi: 10.1517/17460441.2012.674510. Epub 2012 Mar 22. Review.

PMID:
22435452
4.

Novel trends in high-throughput screening.

Mayr LM, Bojanic D.

Curr Opin Pharmacol. 2009 Oct;9(5):580-8. doi: 10.1016/j.coph.2009.08.004. Epub 2009 Sep 21. Review.

PMID:
19775937
5.

The Role of Historical Bioactivity Data in the Deconvolution of Phenotypic Screens.

Bornot A, Blackett C, Engkvist O, Murray C, Bendtsen C.

J Biomol Screen. 2014 Jun;19(5):696-706. doi: 10.1177/1087057113518966. Epub 2014 Jan 17.

PMID:
24441646
6.

Novel methods and approaches to acute lymphoblastic leukemia drug discovery.

Wei MC, Cleary ML.

Expert Opin Drug Discov. 2014 Dec;9(12):1435-46. doi: 10.1517/17460441.2014.956720. Epub 2014 Sep 12. Review.

PMID:
25212992
7.

The development of high-content screening (HCS) technology and its importance to drug discovery.

Fraietta I, Gasparri F.

Expert Opin Drug Discov. 2016;11(5):501-14. doi: 10.1517/17460441.2016.1165203. Epub 2016 Mar 28. Review.

PMID:
26971542
8.

Novel drug discovery for Chagas disease.

Moraes CB, Franco CH.

Expert Opin Drug Discov. 2016;11(5):447-55. doi: 10.1517/17460441.2016.1160883. Epub 2016 Apr 1. Review.

PMID:
26967915
9.

Enhancement of Plant Productivity in the Post-Genomics Era.

Thao NP, Tran LS.

Curr Genomics. 2016 Aug;17(4):295-6. doi: 10.2174/138920291704160607182507.

10.

Functional Genomics in Pharmaceutical Drug Discovery.

Adams R, Steckel M, Nicke B.

Handb Exp Pharmacol. 2016;232:25-41. doi: 10.1007/164_2015_27. Review.

PMID:
26330261
11.

Chemical genomics and emerging DNA technologies in the identification of drug mechanisms and drug targets.

Olsen LC, Færgeman NJ.

Curr Top Med Chem. 2012;12(12):1331-45. Review.

PMID:
22690680
12.

The complete automation of cell culture: improvements for high-throughput and high-content screening.

Jain S, Sondervan D, Rizzu P, Bochdanovits Z, Caminada D, Heutink P.

J Biomol Screen. 2011 Sep;16(8):932-9. doi: 10.1177/1087057111413920. Epub 2011 Jul 20.

PMID:
21775700
13.

High-throughput fluorescence imaging approaches for drug discovery using in vitro and in vivo three-dimensional models.

Martinez NJ, Titus SA, Wagner AK, Simeonov A.

Expert Opin Drug Discov. 2015 Dec;10(12):1347-61. doi: 10.1517/17460441.2015.1091814. Epub 2015 Sep 22. Review.

14.

Discovery of novel targets with high throughput RNA interference screening.

Kassner PD.

Comb Chem High Throughput Screen. 2008 Mar;11(3):175-84. Review.

PMID:
18336211
15.

Emerging techniques for the discovery and validation of therapeutic targets for skeletal diseases.

Cho CH, Nuttall ME.

Expert Opin Ther Targets. 2002 Dec;6(6):679-89. Review.

PMID:
12472380
16.

Using iterative cluster merging with improved gap statistics to perform online phenotype discovery in the context of high-throughput RNAi screens.

Yin Z, Zhou X, Bakal C, Li F, Sun Y, Perrimon N, Wong ST.

BMC Bioinformatics. 2008 Jun 5;9:264. doi: 10.1186/1471-2105-9-264.

17.

Application of chemical biology in target identification and drug discovery.

Zhu Y, Xiao T, Lei S, Zhou F, Wang MW.

Arch Pharm Res. 2015 Sep;38(9):1642-50. doi: 10.1007/s12272-015-0643-2. Epub 2015 Aug 5. Review.

PMID:
26242900
18.

Fulfilling the promise: drug discovery in the post-genomic era.

Chanda SK, Caldwell JS.

Drug Discov Today. 2003 Feb 15;8(4):168-74. Review.

PMID:
12581711
19.

High content screening in neurodegenerative diseases.

Jain S, van Kesteren RE, Heutink P.

J Vis Exp. 2012 Jan 6;(59):e3452. doi: 10.3791/3452.

20.

High-throughput screening and structure-based approaches to hit discovery: is there a clear winner?

Jhoti H, Rees S, Solari R.

Expert Opin Drug Discov. 2013 Dec;8(12):1449-53. doi: 10.1517/17460441.2013.857654. Epub 2013 Nov 9.

PMID:
24206191

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