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Items: 1 to 20 of 81

1.

Cancer heterogeneity: origins and implications for genetic association studies.

Urbach D, Lupien M, Karagas MR, Moore JH.

Trends Genet. 2012 Nov;28(11):538-43. doi: 10.1016/j.tig.2012.07.001. Epub 2012 Jul 31.

2.

Intra-tumour heterogeneity: a looking glass for cancer?

Marusyk A, Almendro V, Polyak K.

Nat Rev Cancer. 2012 Apr 19;12(5):323-34. doi: 10.1038/nrc3261. Review.

PMID:
22513401
3.

Genetic and epigenetic heterogeneity in cancer: a genome-centric perspective.

Heng HH, Bremer SW, Stevens JB, Ye KJ, Liu G, Ye CJ.

J Cell Physiol. 2009 Sep;220(3):538-47. doi: 10.1002/jcp.21799. Review.

PMID:
19441078
4.

Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies.

Kitsios GD, Dahabreh IJ, Trikalinos TA, Schmid CH, Huggins GS, Kent DM.

Circ Cardiovasc Genet. 2011 Feb;4(1):58-67. doi: 10.1161/CIRCGENETICS.110.957738. Epub 2010 Dec 13.

5.

The causes and consequences of genetic heterogeneity in cancer evolution.

Burrell RA, McGranahan N, Bartek J, Swanton C.

Nature. 2013 Sep 19;501(7467):338-45. doi: 10.1038/nature12625. Review.

PMID:
24048066
6.

Implications of genetic heterogeneity in cancer.

Schmitt MW, Prindle MJ, Loeb LA.

Ann N Y Acad Sci. 2012 Sep;1267:110-6. doi: 10.1111/j.1749-6632.2012.06590.x.

7.

Neurofibromatosis type 1: from genotype to phenotype.

Pasmant E, Vidaud M, Vidaud D, Wolkenstein P.

J Med Genet. 2012 Aug;49(8):483-9. doi: 10.1136/jmedgenet-2012-100978. Review.

PMID:
22889851
8.

Genetic and epigenetic heterogeneity in cancer: the ultimate challenge for drug therapy.

Heng HH, Liu G, Stevens JB, Bremer SW, Ye KJ, Ye CJ.

Curr Drug Targets. 2010 Oct;11(10):1304-16. Review.

PMID:
20840073
9.

Genetic and phenotypic heterogeneity of human malignancies: finding order in chaos.

Shackney SE, Shankey TV.

Cytometry. 1995 Sep 1;21(1):2-5. Review.

10.

[The bewildering complexity of cancer].

Jordan B.

Med Sci (Paris). 2011 Aug-Sep;27(8-9):781-6. doi: 10.1051/medsci/2011278022. Epub 2011 Aug 31. French. No abstract available.

11.

The challenge of intratumour heterogeneity in precision medicine.

Seoane J, De Mattos-Arruda L.

J Intern Med. 2014 Jul;276(1):41-51. doi: 10.1111/joim.12240. Review.

12.

[Tumor genetic heterogeneity].

Yang YL, Chu JY, Wang MR.

Yi Chuan. 2013 Jan;35(1):1-9. Review. Chinese.

PMID:
23357259
13.

The emerging genetics of primary ciliary dyskinesia.

Zariwala MA, Omran H, Ferkol TW.

Proc Am Thorac Soc. 2011 Sep;8(5):430-3. doi: 10.1513/pats.201103-023SD. Review.

14.

Beyond genome-wide association studies: genetic heterogeneity and individual predisposition to cancer.

Galvan A, Ioannidis JP, Dragani TA.

Trends Genet. 2010 Mar;26(3):132-41. doi: 10.1016/j.tig.2009.12.008. Epub 2010 Jan 26. Review.

15.

Dissecting cancer heterogeneity with a probabilistic genotype-phenotype model.

Cho DY, Przytycka TM.

Nucleic Acids Res. 2013 Sep;41(17):8011-20. doi: 10.1093/nar/gkt577. Epub 2013 Jul 2.

16.

Tumor heterogeneity: causes and consequences.

Marusyk A, Polyak K.

Biochim Biophys Acta. 2010 Jan;1805(1):105-17. doi: 10.1016/j.bbcan.2009.11.002. Epub 2009 Nov 18. Review.

17.

Oncogenes in non-small-cell lung cancer: emerging connections and novel therapeutic dynamics.

Stella GM, Luisetti M, Pozzi E, Comoglio PM.

Lancet Respir Med. 2013 May;1(3):251-61. doi: 10.1016/S2213-2600(13)70009-2. Epub 2013 Mar 1. Review.

PMID:
24429131
18.

The role of individual susceptibility in cancer burden related to environmental exposure.

Bartsch H, Hietanen E.

Environ Health Perspect. 1996 May;104 Suppl 3:569-77. Review.

19.

Breast cancer genome heterogeneity: a challenge to personalised medicine?

Swanton C, Burrell RA, Futreal PA.

Breast Cancer Res. 2011 Feb 1;13(1):104. doi: 10.1186/bcr2807.

20.

Breast cancer intratumor genetic heterogeneity: causes and implications.

Ng CK, Pemberton HN, Reis-Filho JS.

Expert Rev Anticancer Ther. 2012 Aug;12(8):1021-32. doi: 10.1586/era.12.85. Review.

PMID:
23030222

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