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Items: 1 to 20 of 92

1.

A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation.

Koziolek EJ, Donoghue JF, Bentley JD, Lovrecz G, Dolezal O, Ward CW, Rothacker J, Nice EC, Burgess AW, Hafner M, Johns TG, Adams TE.

Growth Factors. 2012 Oct;30(5):310-9. Epub 2012 Aug 2.

PMID:
22856597
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Heregulin (HRG)-induced mitogenic signaling and cytotoxic activity of a HRG/PE40 ligand toxin in human breast cancer cells.

Fiddes RJ, Janes PW, Sanderson GM, Sivertsen SP, Sutherland RL, Daly RJ.

Cell Growth Differ. 1995 Dec;6(12):1567-77.

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Herstatin inhibits heregulin-mediated breast cancer cell growth and overcomes tamoxifen resistance in breast cancer cells that overexpress HER-2.

Jhabvala-Romero F, Evans A, Guo S, Denton M, Clinton GM.

Oncogene. 2003 Nov 6;22(50):8178-86.

PMID:
14603258
11.

A computational model on the modulation of mitogen-activated protein kinase (MAPK) and Akt pathways in heregulin-induced ErbB signalling.

Hatakeyama M, Kimura S, Naka T, Kawasaki T, Yumoto N, Ichikawa M, Kim JH, Saito K, Saeki M, Shirouzu M, Yokoyama S, Konagaya A.

Biochem J. 2003 Jul 15;373(Pt 2):451-63.

12.

Granulosa cell tumors express erbB4 and are sensitive to the cytotoxic action of heregulin-beta2/PE40.

Furger C, Fiddes RJ, Quinn DI, Bova RJ, Daly RJ, Sutherland RL.

Cancer Res. 1998 May 1;58(9):1773-8.

13.

Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4.

Fitzpatrick VD, Pisacane PI, Vandlen RL, Sliwkowski MX.

FEBS Lett. 1998 Jul 10;431(1):102-6.

14.

Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1.

Hutcheson IR, Goddard L, Barrow D, McClelland RA, Francies HE, Knowlden JM, Nicholson RI, Gee JM.

Breast Cancer Res. 2011 Mar 11;13(2):R29. doi: 10.1186/bcr2848.

17.

Epidermal growth factor and betacellulin mediate signal transduction through co-expressed ErbB2 and ErbB3 receptors.

Alimandi M, Wang LM, Bottaro D, Lee CC, Kuo A, Frankel M, Fedi P, Tang C, Lippman M, Pierce JH.

EMBO J. 1997 Sep 15;16(18):5608-17.

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Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration.

Bourguignon LY, Gilad E, Peyrollier K.

J Biol Chem. 2007 Jul 6;282(27):19426-41. Epub 2007 May 10.

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