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Items: 1 to 20 of 123

1.

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome.

Slape CI, Saw J, Jowett JB, Aplan PD, Strasser A, Jane SM, Curtis DJ.

Blood. 2012 Sep 20;120(12):2475-83. Epub 2012 Jul 31.

2.

Loss of p53 accelerates the complications of myelodysplastic syndrome in a NUP98-HOXD13-driven mouse model.

Xu H, Menendez S, Schlegelberger B, Bae N, Aplan PD, Göhring G, Deblasio TR, Nimer SD.

Blood. 2012 Oct 11;120(15):3089-97. doi: 10.1182/blood-2012-01-405332. Epub 2012 Aug 27.

3.

The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation.

Song SJ, Ito K, Ala U, Kats L, Webster K, Sun SM, Jongen-Lavrencic M, Manova-Todorova K, Teruya-Feldstein J, Avigan DE, Delwel R, Pandolfi PP.

Cell Stem Cell. 2013 Jul 3;13(1):87-101. doi: 10.1016/j.stem.2013.06.003.

4.

Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome.

Chung YJ, Robert C, Gough SM, Rassool FV, Aplan PD.

Leuk Res. 2014 Jan;38(1):95-102. doi: 10.1016/j.leukres.2013.07.008. Epub 2013 Aug 16.

5.

Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome.

Balderman SR, Li AJ, Hoffman CM, Frisch BJ, Goodman AN, LaMere MW, Georger MA, Evans AG, Liesveld JL, Becker MW, Calvi LM.

Blood. 2016 Feb 4;127(5):616-25. doi: 10.1182/blood-2015-06-653113. Epub 2015 Dec 4.

6.

Overexpression of Bcl2 protein predicts chemoresistance in acute myeloid leukemia: its correlation with FLT3.

Mehta SV, Shukla SN, Vora HH.

Neoplasma. 2013;60(6):666-75. doi: 10.4149/neo_2013_085.

PMID:
23906301
7.

Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect.

Gough SM, Chung YJ, Aplan PD.

PLoS One. 2012;7(5):e36876. doi: 10.1371/journal.pone.0036876. Epub 2012 May 11.

8.

SLC7A5 act as a potential leukemic transformation target gene in myelodysplastic syndrome.

Ma Y, Song J, Chen B, Xu X, Lin G.

Oncotarget. 2016 Feb 9;7(6):6566-75. doi: 10.18632/oncotarget.6512.

9.

Plzf drives MLL-fusion-mediated leukemogenesis specifically in long-term hematopoietic stem cells.

Ono R, Masuya M, Nakajima H, Enomoto Y, Miyata E, Nakamura A, Ishii S, Suzuki K, Shibata-Minoshima F, Katayama N, Kitamura T, Nosaka T.

Blood. 2013 Aug 15;122(7):1271-83. doi: 10.1182/blood-2012-09-456665. Epub 2013 Jul 9.

10.
11.

CXCL12+ stromal cells as bone marrow niche for CD34+ hematopoietic cells and their association with disease progression in myelodysplastic syndromes.

Abe-Suzuki S, Kurata M, Abe S, Onishi I, Kirimura S, Nashimoto M, Murayama T, Hidaka M, Kitagawa M.

Lab Invest. 2014 Nov;94(11):1212-23. doi: 10.1038/labinvest.2014.110. Epub 2014 Sep 8.

12.

miR-378 inhibits cell growth and enhances apoptosis in human myelodysplastic syndromes.

Kuang X, Wei C, Zhang T, Yang Z, Chi J, Wang L.

Int J Oncol. 2016 Nov;49(5):1921-1930. doi: 10.3892/ijo.2016.3689. Epub 2016 Sep 13.

PMID:
27633496
13.

Genomic loss of EZH2 leads to epigenetic modifications and overexpression of the HOX gene clusters in myelodysplastic syndrome.

Xu F, Liu L, Chang CK, He Q, Wu LY, Zhang Z, Shi WH, Guo J, Zhu Y, Zhao YS, Gu SC, Fei CM, Li X.

Oncotarget. 2016 Feb 16;7(7):8119-30. doi: 10.18632/oncotarget.6992.

14.

NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men.

Slape C, Lin YW, Hartung H, Zhang Z, Wolff L, Aplan PD.

J Natl Cancer Inst Monogr. 2008;(39):64-8. doi: 10.1093/jncimonographs/lgn014.

15.

Brief report: Loss of p15Ink4b accelerates development of myeloid neoplasms in Nup98-HoxD13 transgenic mice.

Humeniuk R, Koller R, Bies J, Aplan P, Wolff L.

Stem Cells. 2014 May;32(5):1361-6. doi: 10.1002/stem.1635.

16.

Altered oncoprotein expression and apoptosis in myelodysplastic syndrome marrow cells.

Rajapaksa R, Ginzton N, Rott LS, Greenberg PL.

Blood. 1996 Dec 1;88(11):4275-87.

17.

Molecular mechanism of microRNA involvement in genesis of myelodysplastic syndrome and its transformation to acute myeloid leukemia.

Liao R, Xu Y, Chen M, Chen X, Zhan X, Sun J.

Hematology. 2013 Jul;18(4):191-7. doi: 10.1179/1607845412Y.0000000053. Epub 2013 Jan 3. Review.

PMID:
23321417
18.

Secretion and Expression of Matrix Metalloproteinase-2 and 9 from Bone Marrow Mononuclear Cells in Myelodysplastic Syndrome and Acute Myeloid Leukemia.

Chaudhary AK, Chaudhary S, Ghosh K, Shanmukaiah C, Nadkarni AH.

Asian Pac J Cancer Prev. 2016;17(3):1519-29.

20.

MicroRNA-9 promotes proliferation of leukemia cells in adult CD34-positive acute myeloid leukemia with normal karyotype by downregulation of Hes1.

Tian C, You MJ, Yu Y, Zhu L, Zheng G, Zhang Y.

Tumour Biol. 2016 Jun;37(6):7461-71. doi: 10.1007/s13277-015-4581-x. Epub 2015 Dec 17.

PMID:
26678889

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