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Items: 1 to 20 of 125

1.

Associations between polymorphisms in the AHR and CYP1A1-CYP1A2 gene regions and habitual caffeine consumption.

Josse AR, Da Costa LA, Campos H, El-Sohemy A.

Am J Clin Nutr. 2012 Sep;96(3):665-71. doi: 10.3945/ajcn.112.038794. Epub 2012 Aug 1.

2.

Influence of CYP1A1/CYP1A2 and AHR polymorphisms on systemic olanzapine exposure.

Söderberg MM, Haslemo T, Molden E, Dahl ML.

Pharmacogenet Genomics. 2013 May;23(5):279-85. doi: 10.1097/FPC.0b013e3283602876.

PMID:
23492908
3.

Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.

Sulem P, Gudbjartsson DF, Geller F, Prokopenko I, Feenstra B, Aben KK, Franke B, den Heijer M, Kovacs P, Stumvoll M, Mägi R, Yanek LR, Becker LC, Boyd HA, Stacey SN, Walters GB, Jonasdottir A, Thorleifsson G, Holm H, Gudjonsson SA, Rafnar T, Björnsdottir G, Becker DM, Melbye M, Kong A, Tönjes A, Thorgeirsson T, Thorsteinsdottir U, Kiemeney LA, Stefansson K.

Hum Mol Genet. 2011 May 15;20(10):2071-7. doi: 10.1093/hmg/ddr086. Epub 2011 Feb 28.

4.

Phenotype refinement strengthens the association of AHR and CYP1A1 genotype with caffeine consumption.

McMahon G, Taylor AE, Davey Smith G, Munafò MR.

PLoS One. 2014 Jul 30;9(7):e103448. doi: 10.1371/journal.pone.0103448. eCollection 2014.

5.

Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption.

Cornelis MC, El-Sohemy A, Campos H.

Am J Clin Nutr. 2007 Jul;86(1):240-4.

6.

Coffee intake and risk of obesity, metabolic syndrome and type 2 diabetes: a Mendelian randomization study.

Nordestgaard AT, Thomsen M, Nordestgaard BG.

Int J Epidemiol. 2015 Apr;44(2):551-65. doi: 10.1093/ije/dyv083. Epub 2015 May 22.

PMID:
26002927
7.

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.

Cornelis MC, Monda KL, Yu K, Paynter N, Azzato EM, Bennett SN, Berndt SI, Boerwinkle E, Chanock S, Chatterjee N, Couper D, Curhan G, Heiss G, Hu FB, Hunter DJ, Jacobs K, Jensen MK, Kraft P, Landi MT, Nettleton JA, Purdue MP, Rajaraman P, Rimm EB, Rose LM, Rothman N, Silverman D, Stolzenberg-Solomon R, Subar A, Yeager M, Chasman DI, van Dam RM, Caporaso NE.

PLoS Genet. 2011 Apr;7(4):e1002033. doi: 10.1371/journal.pgen.1002033. Epub 2011 Apr 7.

8.

Coffee, CYP1A2 genotype, and risk of myocardial infarction.

Cornelis MC, El-Sohemy A, Kabagambe EK, Campos H.

JAMA. 2006 Mar 8;295(10):1135-41.

PMID:
16522833
9.

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM.

Amin N, Byrne E, Johnson J, Chenevix-Trench G, Walter S, Nolte IM; kConFab Investigators., Vink JM, Rawal R, Mangino M, Teumer A, Keers JC, Verwoert G, Baumeister S, Biffar R, Petersmann A, Dahmen N, Doering A, Isaacs A, Broer L, Wray NR, Montgomery GW, Levy D, Psaty BM, Gudnason V, Chakravarti A, Sulem P, Gudbjartsson DF, Kiemeney LA, Thorsteinsdottir U, Stefansson K, van Rooij FJ, Aulchenko YS, Hottenga JJ, Rivadeneira FR, Hofman A, Uitterlinden AG, Hammond CJ, Shin SY, Ikram A, Witteman JC, Janssens AC, Snieder H, Tiemeier H, Wolfenbuttel BH, Oostra BA, Heath AC, Wichmann E, Spector TD, Grabe HJ, Boomsma DI, Martin NG, van Duijn CM.

Mol Psychiatry. 2012 Nov;17(11):1116-29. doi: 10.1038/mp.2011.101. Epub 2011 Aug 30.

10.

The CYP1A2 genotype modifies the association between coffee consumption and breast cancer risk among BRCA1 mutation carriers.

Kotsopoulos J, Ghadirian P, El-Sohemy A, Lynch HT, Snyder C, Daly M, Domchek S, Randall S, Karlan B, Zhang P, Zhang S, Sun P, Narod SA.

Cancer Epidemiol Biomarkers Prev. 2007 May;16(5):912-6.

11.

Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer.

Kotsopoulos J, Vitonis AF, Terry KL, De Vivo I, Cramer DW, Hankinson SE, Tworoger SS.

Cancer Causes Control. 2009 Apr;20(3):335-44. doi: 10.1007/s10552-008-9247-1. Epub 2008 Oct 21.

12.

Ah receptor, CYP1A1, CYP1A2 and CYP1B1 gene polymorphisms are not involved in the risk of recurrent pregnancy loss.

Saijo Y, Sata F, Yamada H, Suzuki K, Sasaki S, Kondo T, Gong YY, Kato EH, Shimada S, Morikawa M, Minakami H, Kishi R.

Mol Hum Reprod. 2004 Oct;10(10):729-33. Epub 2004 Aug 6.

PMID:
15299091
13.

CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.

Terashima J, Goto S, Hattori H, Hoshi S, Ushirokawa M, Kudo K, Habano W, Ozawa S.

Drug Metab Pharmacokinet. 2015 Dec;30(6):434-40. doi: 10.1016/j.dmpk.2015.10.001. Epub 2015 Oct 26.

PMID:
26643992
14.

Gender and ethnicity modify the association between the CYP1A2 rs762551 polymorphism and habitual coffee intake: evidence from a meta-analysis.

Denden S, Bouden B, Haj Khelil A, Ben Chibani J, Hamdaoui MH.

Genet Mol Res. 2016 Apr 4;15(2). doi: 10.4238/gmr.15027487.

15.

Coffee, ADORA2A, and CYP1A2: the caffeine connection in Parkinson's disease.

Popat RA, Van Den Eeden SK, Tanner CM, Kamel F, Umbach DM, Marder K, Mayeux R, Ritz B, Ross GW, Petrovitch H, Topol B, McGuire V, Costello S, Manthripragada AD, Southwick A, Myers RM, Nelson LM.

Eur J Neurol. 2011 May;18(5):756-65. doi: 10.1111/j.1468-1331.2011.03353.x. Epub 2011 Jan 31.

16.

Palmatine activates AhR and upregulates CYP1A activity in HepG2 cells but not in human hepatocytes.

Vrba J, Havlikova M, Gerhardova D, Ulrichova J.

Toxicol In Vitro. 2014 Jun;28(4):693-9. doi: 10.1016/j.tiv.2014.02.008. Epub 2014 Feb 27.

PMID:
24583342
17.

Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes.

Vrzal R, Stejskalova L, Monostory K, Maurel P, Bachleda P, Pavek P, Dvorak Z.

Chem Biol Interact. 2009 May 15;179(2-3):288-96. doi: 10.1016/j.cbi.2008.10.035. Epub 2008 Nov 5.

PMID:
19022236
18.

The influence of genetic polymorphisms in Ahr, CYP1A1, CYP1A2, CYP1B1, GST M1, GST T1 and UGT1A1 on urine 1-hydroxypyrene glucuronide concentrations in healthy subjects from Rio Grande do Sul, Brazil.

Abnet CC, Fagundes RB, Strickland PT, Kamangar F, Roth MJ, Taylor PR, Dawsey SM.

Carcinogenesis. 2007 Jan;28(1):112-7. Epub 2006 Jul 24.

PMID:
16864595
19.

High coffee intake, but not caffeine, is associated with reduced estrogen receptor negative and postmenopausal breast cancer risk with no effect modification by CYP1A2 genotype.

Lowcock EC, Cotterchio M, Anderson LN, Boucher BA, El-Sohemy A.

Nutr Cancer. 2013;65(3):398-409. doi: 10.1080/01635581.2013.768348.

PMID:
23530639
20.

Generation of a 'humanized' hCYP1A1_1A2_Cyp1a1/1a2(-/-)_Ahrd mouse line harboring the poor-affinity aryl hydrocarbon receptor.

Shi Z, Chen Y, Dong H, Amos-Kroohs RM, Nebert DW.

Biochem Biophys Res Commun. 2008 Nov 28;376(4):775-80. doi: 10.1016/j.bbrc.2008.09.068. Epub 2008 Sep 22.

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