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Items: 1 to 20 of 108

1.

Suppression of autoimmune arthritis by Celastrus-derived Celastrol through modulation of pro-inflammatory chemokines.

Venkatesha SH, Astry B, Nanjundaiah SM, Yu H, Moudgil KD.

Bioorg Med Chem. 2012 Sep 1;20(17):5229-34. doi: 10.1016/j.bmc.2012.06.050. Epub 2012 Jul 7.

2.

Microarray-based gene expression profiling reveals the mediators and pathways involved in the anti-arthritic activity of Celastrus-derived Celastrol.

Yu H, Venkatesha SH, Moudgil KD.

Int Immunopharmacol. 2012 Aug;13(4):499-506. doi: 10.1016/j.intimp.2012.05.015. Epub 2012 Jun 2.

3.

Celastrus-derived celastrol suppresses autoimmune arthritis by modulating antigen-induced cellular and humoral effector responses.

Venkatesha SH, Yu H, Rajaiah R, Tong L, Moudgil KD.

J Biol Chem. 2011 Apr 29;286(17):15138-46. doi: 10.1074/jbc.M111.226365. Epub 2011 Mar 14.

4.

Celastrus and its bioactive celastrol protect against bone damage in autoimmune arthritis by modulating osteoimmune cross-talk.

Nanjundaiah SM, Venkatesha SH, Yu H, Tong L, Stains JP, Moudgil KD.

J Biol Chem. 2012 Jun 22;287(26):22216-26. doi: 10.1074/jbc.M112.356816. Epub 2012 May 1.

5.

Modified huo-luo-xiao-ling dan suppresses adjuvant arthritis by inhibiting chemokines and matrix-degrading enzymes.

Nanjundaiah SM, Lee DY, Ma Z, Fong HH, Lao L, Berman BM, Moudgil KD.

Evid Based Complement Alternat Med. 2012;2012:589256. doi: 10.1155/2012/589256. Epub 2012 Mar 7.

6.

Decrease of CD68 Synovial Macrophages in Celastrol Treated Arthritic Rats.

Cascão R, Vidal B, Lopes IP, Paisana E, Rino J, Moita LF, Fonseca JE.

PLoS One. 2015 Dec 11;10(12):e0142448. doi: 10.1371/journal.pone.0142448. eCollection 2015.

8.

Control of autoimmune inflammation by celastrol, a natural triterpenoid.

Venkatesha SH, Dudics S, Astry B, Moudgil KD.

Pathog Dis. 2016 Aug;74(6). pii: ftw059. doi: 10.1093/femspd/ftw059. Epub 2016 Jul 11. Review.

PMID:
27405485
9.

Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ.

Astry B, Venkatesha SH, Laurence A, Christensen-Quick A, Garzino-Demo A, Frieman MB, O'Shea JJ, Moudgil KD.

Clin Immunol. 2015 Apr;157(2):228-38. doi: 10.1016/j.clim.2015.01.011. Epub 2015 Feb 7.

10.

Anti-invasive effects of celastrol in hypoxia-induced fibroblast-like synoviocyte through suppressing of HIF-1α/CXCR4 signaling pathway.

Li GQ, Liu D, Zhang Y, Qian YY, Zhu YD, Guo SY, Sunagawa M, Hisamitsu T, Liu YQ.

Int Immunopharmacol. 2013 Dec;17(4):1028-36. doi: 10.1016/j.intimp.2013.10.006. Epub 2013 Oct 18.

PMID:
24144813
11.

Celastrus treatment modulates antigen-induced gene expression in lymphoid cells of arthritic rats.

Yu H, Venkatesha SH, Nanjundaiah S, Tong L, Moudgil KD.

Int J Immunopathol Pharmacol. 2012 Apr-Jun;25(2):455-66.

12.

Effective treatment of rat adjuvant-induced arthritis by celastrol.

Cascão R, Vidal B, Raquel H, Neves-Costa A, Figueiredo N, Gupta V, Fonseca JE, Moita LF.

Autoimmun Rev. 2012 Oct;11(12):856-62. doi: 10.1016/j.autrev.2012.02.022. Epub 2012 Mar 3.

13.

Tinospora cordifolia inhibits autoimmune arthritis by regulating key immune mediators of inflammation and bone damage.

Sannegowda KM, Venkatesha SH, Moudgil KD.

Int J Immunopathol Pharmacol. 2015 Dec;28(4):521-31. doi: 10.1177/0394632015608248. Epub 2015 Oct 14.

PMID:
26467057
14.

Pristimerin, a naturally occurring triterpenoid, protects against autoimmune arthritis by modulating the cellular and soluble immune mediators of inflammation and tissue damage.

Tong L, Nanjundaiah SM, Venkatesha SH, Astry B, Yu H, Moudgil KD.

Clin Immunol. 2014 Dec;155(2):220-30. doi: 10.1016/j.clim.2014.09.014. Epub 2014 Oct 13.

PMID:
25308129
15.

Green tea extract inhibits chemokine production, but up-regulates chemokine receptor expression, in rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis.

Marotte H, Ruth JH, Campbell PL, Koch AE, Ahmed S.

Rheumatology (Oxford). 2010 Mar;49(3):467-79. doi: 10.1093/rheumatology/kep397. Epub 2009 Dec 23.

16.

Kirenol exerts a potent anti-arthritic effect in collagen-induced arthritis by modifying the T cells balance.

Lu Y, Xiao J, Wu ZW, Wang ZM, Hu J, Fu HZ, Chen YY, Qian RQ.

Phytomedicine. 2012 Jul 15;19(10):882-9. doi: 10.1016/j.phymed.2012.04.010. Epub 2012 Jun 4.

PMID:
22673798
17.

Altered Th17/Treg balance and dysregulated IL-1β response influence susceptibility/resistance to experimental autoimmune arthritis.

Venkatesha SH, Dudics S, Weingartner E, So EC, Pedra J, Moudgil KD.

Int J Immunopathol Pharmacol. 2015 Sep;28(3):318-28. doi: 10.1177/0394632015595757. Epub 2015 Jul 30.

PMID:
26227656
18.

Grape seed proanthocyanidin extract has potent anti-arthritic effects on collagen-induced arthritis by modifying the T cell balance.

Ahmad SF, Zoheir KM, Abdel-Hamied HE, Ashour AE, Bakheet SA, Attia SM, Abd-Allah AR.

Int Immunopharmacol. 2013 Sep;17(1):79-87. doi: 10.1016/j.intimp.2013.05.026. Epub 2013 Jun 10.

PMID:
23759204
19.

Kinetics and interplay of mediators of inflammation-induced bone damage in the course of adjuvant arthritis.

Nanjundaiah SM, Stains JP, Moudgil KD.

Int J Immunopathol Pharmacol. 2013 Jan-Mar;26(1):37-48.

20.

Celastrol inhibits interleukin-17A-stimulated rheumatoid fibroblast-like synoviocyte migration and invasion through suppression of NF-κB-mediated matrix metalloproteinase-9 expression.

Li GQ, Zhang Y, Liu D, Qian YY, Zhang H, Guo SY, Sunagawa M, Hisamitsu T, Liu YQ.

Int Immunopharmacol. 2012 Dec;14(4):422-31. doi: 10.1016/j.intimp.2012.08.016. Epub 2012 Sep 3.

PMID:
22954486

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