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Expressional changes in cerebrovascular receptors after experimental transient forebrain ischemia.

Johansson S, Povlsen GK, Edvinsson L.

PLoS One. 2012;7(7):e41852. doi: 10.1371/journal.pone.0041852. Epub 2012 Jul 27.


Early MEK1/2 inhibition after global cerebral ischemia in rats reduces brain damage and improves outcome by preventing delayed vasoconstrictor receptor upregulation.

Johansson SE, Larsen SS, Povlsen GK, Edvinsson L.

PLoS One. 2014 Mar 18;9(3):e92417. doi: 10.1371/journal.pone.0092417. eCollection 2014.


In vivo experimental stroke and in vitro organ culture induce similar changes in vasoconstrictor receptors and intracellular calcium handling in rat cerebral arteries.

Povlsen GK, Waldsee R, Ahnstedt H, Kristiansen KA, Johansen FF, Edvinsson L.

Exp Brain Res. 2012 Jun;219(4):507-20. doi: 10.1007/s00221-012-3108-6. Epub 2012 May 15.


MAPK signaling pathway regulates cerebrovascular receptor expression in human cerebral arteries.

Ansar S, Eftekhari S, Waldsee R, Nilsson E, Nilsson O, Säveland H, Edvinsson L.

BMC Neurosci. 2013 Jan 23;14:12. doi: 10.1186/1471-2202-14-12.


ERK1/2 inhibition attenuates cerebral blood flow reduction and abolishes ET(B) and 5-HT(1B) receptor upregulation after subarachnoid hemorrhage in rat.

Beg SA, Hansen-Schwartz JA, Vikman PJ, Xu CB, Edvinsson LI.

J Cereb Blood Flow Metab. 2006 Jun;26(6):846-56.


Cerebrovascular ETB, 5-HT1B, and AT1 receptor upregulation correlates with reduction in regional CBF after subarachnoid hemorrhage.

Ansar S, Vikman P, Nielsen M, Edvinsson L.

Am J Physiol Heart Circ Physiol. 2007 Dec;293(6):H3750-8. Epub 2007 Sep 14.


Early events triggering delayed vasoconstrictor receptor upregulation and cerebral ischemia after subarachnoid hemorrhage.

Povlsen GK, Johansson SE, Larsen CC, Samraj AK, Edvinsson L.

BMC Neurosci. 2013 Mar 15;14:34. doi: 10.1186/1471-2202-14-34.


Permanent distal occlusion of middle cerebral artery in rat causes local increased ETB, 5-HT₁B and AT₁ receptor-mediated contractility downstream of occlusion.

Rasmussen MN, Hornbak M, Larsen SS, Sheykhzade M, Edvinsson L.

J Vasc Res. 2013;50(5):396-409. doi: 10.1159/000354242. Epub 2013 Aug 29.


Protein kinase C inhibition prevents upregulation of vascular ET(B) and 5-HT(1B) receptors and reverses cerebral blood flow reduction after subarachnoid haemorrhage in rats.

Beg SS, Hansen-Schwartz JA, Vikman PJ, Xu CB, Edvinsson LI.

J Cereb Blood Flow Metab. 2007 Jan;27(1):21-32. Epub 2006 May 17.


Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries.

Ahnstedt H, Cao L, Krause DN, Warfvinge K, Säveland H, Nilsson OG, Edvinsson L.

PLoS One. 2013 Apr 29;8(4):e62698. doi: 10.1371/journal.pone.0062698. Print 2013.


Intracellular pathways involved in upregulation of vascular endothelin type B receptors in cerebral arteries of the rat.

Henriksson M, Stenman E, Edvinsson L.

Stroke. 2003 Jun;34(6):1479-83. Epub 2003 May 15.


Cerebrovascular endothelin-1 hyper-reactivity is associated with transient receptor potential canonical channels 1 and 6 activation and delayed cerebral hypoperfusion after forebrain ischaemia in rats.

Johansson SE, Andersen XE, Hansen RH, Povlsen GK, Edvinsson L.

Acta Physiol (Oxf). 2015 Jul;214(3):376-89. doi: 10.1111/apha.12519. Epub 2015 Jun 4.


Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease.

Dimitrijevic I, Edvinsson ML, Chen Q, Malmsjö M, Kimblad PO, Edvinsson L.

BMC Cardiovasc Disord. 2009 Aug 25;9:40. doi: 10.1186/1471-2261-9-40.


Rapid functional upregulation of vasocontractile endothelin ETB receptors in rat coronary arteries.

Skovsted GF, Pedersen AF, Larsen R, Sheykhzade M, Edvinsson L.

Life Sci. 2012 Oct 15;91(13-14):593-9. doi: 10.1016/j.lfs.2012.02.009. Epub 2012 Feb 25.


Cerebral ischemia upregulates vascular endothelin ET(B) receptors in rat.

Stenman E, Malmsjö M, Uddman E, Gidö G, Wieloch T, Edvinsson L.

Stroke. 2002 Sep;33(9):2311-6.


Importance of ERK1/2 in upregulation of endothelin type B receptors in cerebral arteries.

Henriksson M, Xu CB, Edvinsson L.

Br J Pharmacol. 2004 Aug;142(7):1155-61. Epub 2004 Jul 5.


Secondhand cigarette smoke exposure causes upregulation of cerebrovascular 5-HT(1) (B) receptors via the Raf/ERK/MAPK pathway in rats.

Cao L, Xu CB, Zhang Y, Cao YX, Edvinsson L.

Acta Physiol (Oxf). 2013 Jan;207(1):183-93. doi: 10.1111/j.1748-1716.2012.02478.x. Epub 2012 Sep 4.

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