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Items: 1 to 20 of 63

1.

Retroactive signaling in short signaling pathways.

Sepulchre JA, Merajver SD, Ventura AC.

PLoS One. 2012;7(7):e40806. doi: 10.1371/journal.pone.0040806. Epub 2012 Jul 26.

2.

Long signaling cascades tend to attenuate retroactivity.

Ossareh HR, Ventura AC, Merajver SD, Del Vecchio D.

Biophys J. 2011 Apr 6;100(7):1617-26. doi: 10.1016/j.bpj.2011.02.014.

3.

Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity.

Wynn ML, Ventura AC, Sepulchre JA, GarcĂ­a HJ, Merajver SD.

BMC Syst Biol. 2011 Oct 4;5:156. doi: 10.1186/1752-0509-5-156.

4.

Signaling properties of a covalent modification cycle are altered by a downstream target.

Ventura AC, Jiang P, Van Wassenhove L, Del Vecchio D, Merajver SD, Ninfa AJ.

Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10032-7. doi: 10.1073/pnas.0913815107. Epub 2010 May 17.

5.

Emergent properties of networks of biological signaling pathways.

Bhalla US, Iyengar R.

Science. 1999 Jan 15;283(5400):381-7.

6.

Signaling cascades transmit information downstream and upstream but unlikely simultaneously.

Catozzi S, Di-Bella JP, Ventura AC, Sepulchre JA.

BMC Syst Biol. 2016 Aug 25;10(1):84. doi: 10.1186/s12918-016-0303-2.

7.

Regulatory cascades of protein phosphatases: implications for cancer treatment.

Jailkhani N, Chaudhri VK, Rao KV.

Anticancer Agents Med Chem. 2011 Jan;11(1):64-77. Review.

PMID:
21214508
8.

A hidden feedback in signaling cascades is revealed.

Ventura AC, Sepulchre JA, Merajver SD.

PLoS Comput Biol. 2008 Mar 21;4(3):e1000041. doi: 10.1371/journal.pcbi.1000041.

9.

A Discrete Dynamical System Approach to Pathway Activation Profiles of Signaling Cascades.

Catozzi S, Sepulchre JA.

Bull Math Biol. 2017 Aug;79(8):1691-1735. doi: 10.1007/s11538-017-0296-z. Epub 2017 Jun 28.

PMID:
28660544
10.

Automatic decomposition of kinetic models of signaling networks minimizing the retroactivity among modules.

Saez-Rodriguez J, Gayer S, Ginkel M, Gilles ED.

Bioinformatics. 2008 Aug 15;24(16):i213-9. doi: 10.1093/bioinformatics/btn289.

PMID:
18689828
11.

Myosin light chain phosphatase: it gets around.

Brozovich FV.

Circ Res. 2002 Mar 22;90(5):500-2. No abstract available.

12.

A generic model for open signaling cascades with forward activation.

Li Y.

J Math Biol. 2012 Oct;65(4):709-42. doi: 10.1007/s00285-011-0480-y. Epub 2011 Oct 16.

PMID:
22002682
13.

Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes.

Adams DG, Coffee RL Jr, Zhang H, Pelech S, Strack S, Wadzinski BE.

J Biol Chem. 2005 Dec 30;280(52):42644-54. Epub 2005 Oct 20.

14.
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16.

Modularity in signaling systems.

Del Vecchio D.

Phys Biol. 2012 Aug;9(4):045008. doi: 10.1088/1478-3975/9/4/045008. Epub 2012 Aug 7.

PMID:
22871977
17.

Insulin receptor kinase-independent signaling via tyrosine phosphorylation of phosphatase PHLPP1.

Zhang M, Riedel H.

J Cell Biochem. 2009 May 1;107(1):65-75. doi: 10.1002/jcb.22095.

PMID:
19277985
18.

Sensitivity and specificity amplification in signal transduction.

Li G, Qian H.

Cell Biochem Biophys. 2003;39(1):45-59. Review.

PMID:
12835528
19.

Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin.

Melendez J, Turner C, Avraham H, Steinberg SF, Schaefer E, Sussman MA.

J Biol Chem. 2004 Dec 17;279(51):53516-23. Epub 2004 Aug 22.

20.

An algebraic approach to signaling cascades with N layers.

Feliu E, Knudsen M, Andersen LN, Wiuf C.

Bull Math Biol. 2012 Jan;74(1):45-72. doi: 10.1007/s11538-011-9658-0. Epub 2011 Apr 27.

PMID:
21523510

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