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Items: 1 to 20 of 94


Deregulation of XPC and CypA by cyclosporin A: an immunosuppression-independent mechanism of skin carcinogenesis.

Han W, Soltani K, Ming M, He YY.

Cancer Prev Res (Phila). 2012 Sep;5(9):1155-62. doi: 10.1158/1940-6207.CAPR-12-0185-T. Epub 2012 Jul 30.


Immunosuppressive cyclosporin A activates AKT in keratinocytes through PTEN suppression: implications in skin carcinogenesis.

Han W, Ming M, He TC, He YY.

J Biol Chem. 2010 Apr 9;285(15):11369-77. doi: 10.1074/jbc.M109.028142. Epub 2010 Feb 12.


PTEN positively regulates UVB-induced DNA damage repair.

Ming M, Feng L, Shea CR, Soltani K, Zhao B, Han W, Smart RC, Trempus CS, He YY.

Cancer Res. 2011 Aug 1;71(15):5287-95. doi: 10.1158/0008-5472.CAN-10-4614. Epub 2011 Jul 19.


Effect of immunosuppressants tacrolimus and mycophenolate mofetil on the keratinocyte UVB response.

Ming M, Zhao B, Qiang L, He YY.

Photochem Photobiol. 2015 Jan-Feb;91(1):242-7. doi: 10.1111/php.12318. Epub 2014 Aug 12.


Role of AMPK in UVB-induced DNA damage repair and growth control.

Wu CL, Qiang L, Han W, Ming M, Viollet B, He YY.

Oncogene. 2013 May 23;32(21):2682-9. doi: 10.1038/onc.2012.279. Epub 2012 Jul 2.


Dual role of SIRT1 in UVB-induced skin tumorigenesis.

Ming M, Soltani K, Shea CR, Li X, He YY.

Oncogene. 2015 Jan 15;34(3):357-63. doi: 10.1038/onc.2013.583. Epub 2014 Jan 20.


Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.

Wulff BC, Kusewitt DF, VanBuskirk AM, Thomas-Ahner JM, Duncan FJ, Oberyszyn TM.

J Invest Dermatol. 2008 Oct;128(10):2467-73. doi: 10.1038/jid.2008.121. Epub 2008 May 8.


XPC silencing in normal human keratinocytes triggers metabolic alterations that drive the formation of squamous cell carcinomas.

Rezvani HR, Kim AL, Rossignol R, Ali N, Daly M, Mahfouf W, Bellance N, Taïeb A, de Verneuil H, Mazurier F, Bickers DR.

J Clin Invest. 2011 Jan;121(1):195-211. doi: 10.1172/JCI40087. Epub 2010 Dec 1.


Cyclosporine A suppresses keratinocyte cell death through MPTP inhibition in a model for skin cancer in organ transplant recipients.

Norman KG, Canter JA, Shi M, Milne GL, Morrow JD, Sligh JE.

Mitochondrion. 2010 Mar;10(2):94-101. doi: 10.1016/j.mito.2009.10.001. Epub 2009 Oct 31.


Cyclosporin A inhibits nucleotide excision repair via downregulation of the xeroderma pigmentosum group A and G proteins, which is mediated by calcineurin inhibition.

Kuschal C, Thoms KM, Boeckmann L, Laspe P, Apel A, Schön MP, Emmert S.

Exp Dermatol. 2011 Oct;20(10):795-9. doi: 10.1111/j.1600-0625.2011.01320.x. Epub 2011 Jun 24.


Calcineurin inhibitors decrease DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation.

Yarosh DB, Pena AV, Nay SL, Canning MT, Brown DA.

J Invest Dermatol. 2005 Nov;125(5):1020-5.


[Ultraviolet A-induced DNA damage: role in skin cancer].

Beani JC.

Bull Acad Natl Med. 2014 Feb;198(2):273-95. French.


Hypoxia-inducible factor-1alpha regulates the expression of nucleotide excision repair proteins in keratinocytes.

Rezvani HR, Mahfouf W, Ali N, Chemin C, Ged C, Kim AL, de Verneuil H, Taïeb A, Bickers DR, Mazurier F.

Nucleic Acids Res. 2010 Jan;38(3):797-809. doi: 10.1093/nar/gkp1072. Epub 2009 Nov 24.


Genotype-specific Trp53 mutational analysis in ultraviolet B radiation-induced skin cancers in Xpc and Xpc Trp53 mutant mice.

Reis AM, Cheo DL, Meira LB, Greenblatt MS, Bond JP, Nahari D, Friedberg EC.

Cancer Res. 2000 Mar 15;60(6):1571-9.


Phloroglucinol enhances the repair of UVB radiation-induced DNA damage via promotion of the nucleotide excision repair system in vitro and in vivo.

Piao MJ, Ahn MJ, Kang KA, Kim KC, Cha JW, Lee NH, Hyun JW.

DNA Repair (Amst). 2015 Apr;28:131-8. doi: 10.1016/j.dnarep.2015.02.019. Epub 2015 Feb 28.


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