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Items: 1 to 20 of 120

1.

Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries.

Tewari-Singh N, Jain AK, Inturi S, Ammar DA, Agarwal C, Tyagi P, Kompella UB, Enzenauer RW, Petrash JM, Agarwal R.

Toxicol Appl Pharmacol. 2012 Oct 1;264(1):23-31. doi: 10.1016/j.taap.2012.07.014. Epub 2012 Jul 24.

2.

Doxycycline hydrogels as a potential therapy for ocular vesicant injury.

Gordon MK, Desantis A, Deshmukh M, Lacey CJ, Hahn RA, Beloni J, Anumolu SS, Schlager JJ, Gallo MA, Gerecke DR, Heindel ND, Svoboda KK, Babin MC, Sinko PJ.

J Ocul Pharmacol Ther. 2010 Oct;26(5):407-19. doi: 10.1089/jop.2010.0099.

3.

Ocular injuries following sulfur mustard exposure--pathological mechanism and potential therapy.

Kadar T, Dachir S, Cohen L, Sahar R, Fishbine E, Cohen M, Turetz J, Gutman H, Buch H, Brandeis R, Horwitz V, Solomon A, Amir A.

Toxicology. 2009 Sep 1;263(1):59-69. doi: 10.1016/j.tox.2008.10.026. Epub 2008 Nov 17.

PMID:
19061933
4.

Flavanone silibinin treatment attenuates nitrogen mustard-induced toxic effects in mouse skin.

Jain AK, Tewari-Singh N, Inturi S, Kumar D, Orlicky DJ, Agarwal C, White CW, Agarwal R.

Toxicol Appl Pharmacol. 2015 May 15;285(1):71-8. doi: 10.1016/j.taap.2015.03.009. Epub 2015 Mar 16.

5.

Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation.

Tewari-Singh N, Jain AK, Inturi S, Agarwal C, White CW, Agarwal R.

PLoS One. 2012;7(9):e46149. doi: 10.1371/journal.pone.0046149. Epub 2012 Sep 27.

6.

Nitrogen Mustard-Induced Corneal Injury Involves DNA Damage and Pathways Related to Inflammation, Epithelial-Stromal Separation, and Neovascularization.

Goswami DG, Tewari-Singh N, Dhar D, Kumar D, Agarwal C, Ammar DA, Kant R, Enzenauer RW, Petrash JM, Agarwal R.

Cornea. 2016 Feb;35(2):257-66. doi: 10.1097/ICO.0000000000000685.

7.

Efficacy of anti-inflammatory, antibiotic and pleiotropic agents in reversing nitrogen mustard-induced injury in ex vivo cultured rabbit cornea.

Goswami DG, Kant R, Tewari-Singh N, Agarwal R.

Toxicol Lett. 2017 Nov 23. pii: S0378-4274(17)31485-6. doi: 10.1016/j.toxlet.2017.11.026. [Epub ahead of print]

PMID:
29174984
8.

Mustard vesicating agent-induced toxicity in the skin tissue and silibinin as a potential countermeasure.

Tewari-Singh N, Agarwal R.

Ann N Y Acad Sci. 2016 Jun;1374(1):184-92. doi: 10.1111/nyas.13099. Epub 2016 Jun 21. Review.

9.

Treatment of ocular tissues exposed to nitrogen mustard: beneficial effect of zinc desferrioxamine combined with steroids.

Morad Y, Banin E, Averbukh E, Berenshtein E, Obolensky A, Chevion M.

Invest Ophthalmol Vis Sci. 2005 May;46(5):1640-6. Erratum in: Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3483.

PMID:
15851563
10.

Silibinin as a potential therapeutic for sulfur mustard injuries.

Balszuweit F, John H, Schmidt A, Kehe K, Thiermann H, Steinritz D.

Chem Biol Interact. 2013 Dec 5;206(3):496-504. doi: 10.1016/j.cbi.2013.06.010. Epub 2013 Jun 25.

PMID:
23810508
11.

ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure.

DeSantis-Rodrigues A, Chang YC, Hahn RA, Po IP, Zhou P, Lacey CJ, Pillai A, C Young S, Flowers RA 2nd, Gallo MA, Laskin JD, Gerecke DR, Svoboda KK, Heindel ND, Gordon MK.

Invest Ophthalmol Vis Sci. 2016 Apr;57(4):1687-98. doi: 10.1167/iovs.15-17269.

12.

Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.

Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R.

Toxicology. 2014 Jun 5;320:25-33. doi: 10.1016/j.tox.2014.02.013. Epub 2014 Mar 12.

13.

Development of a mouse model for sulfur mustard-induced ocular injury and long-term clinical analysis of injury progression.

Ruff AL, Jarecke AJ, Hilber DJ, Rothwell CC, Beach SL, Dillman JF 3rd.

Cutan Ocul Toxicol. 2013 Jun;32(2):140-9. doi: 10.3109/15569527.2012.731666. Epub 2012 Oct 30.

PMID:
23106216
14.

Endothelial cell damage following sulfur mustard exposure in rabbits and its association with the delayed-onset ocular lesions.

Kadar T, Cohen M, Cohen L, Fishbine E, Sahar R, Brandeis R, Dachir S, Amir A.

Cutan Ocul Toxicol. 2013 Jun;32(2):115-23. doi: 10.3109/15569527.2012.717571. Epub 2012 Oct 30.

PMID:
23106194
15.

The beneficial effects of doxycycline, an inhibitor of matrix metalloproteinases, on sulfur mustard-induced ocular pathologies depend on the injury stage.

Horwitz V, Dachir S, Cohen M, Gutman H, Cohen L, Fishbine E, Brandeis R, Turetz J, Amir A, Gore A, Kadar T.

Curr Eye Res. 2014 Aug;39(8):803-12. doi: 10.3109/02713683.2013.874443. Epub 2014 Feb 6.

PMID:
24502433
16.

Histopathological and immunohistochemical evaluation of nitrogen mustard-induced cutaneous effects in SKH-1 hairless and C57BL/6 mice.

Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R.

Exp Toxicol Pathol. 2014 Mar;66(2-3):129-38. doi: 10.1016/j.etp.2013.11.005. Epub 2013 Dec 25.

17.

Structural, morphological, and functional correlates of corneal endothelial toxicity following corneal exposure to sulfur mustard vapor.

McNutt P, Tuznik K, Nelson M, Adkins A, Lyman M, Glotfelty E, Hughes J, Hamilton T.

Invest Ophthalmol Vis Sci. 2013 Oct 15;54(10):6735-44. doi: 10.1167/iovs.13-12402.

PMID:
24045986
18.

Cutaneous injury-related structural changes and their progression following topical nitrogen mustard exposure in hairless and haired mice.

Tewari-Singh N, Jain AK, Orlicky DJ, White CW, Agarwal R.

PLoS One. 2014 Jan 8;9(1):e85402. doi: 10.1371/journal.pone.0085402. eCollection 2014.

19.

Corneal toxicity induced by vesicating agents and effective treatment options.

Goswami DG, Tewari-Singh N, Agarwal R.

Ann N Y Acad Sci. 2016 Jun;1374(1):193-201. doi: 10.1111/nyas.13121. Epub 2016 Jun 21. Review.

20.

Doxycycline loaded poly(ethylene glycol) hydrogels for healing vesicant-induced ocular wounds.

Anumolu SS, DeSantis AS, Menjoge AR, Hahn RA, Beloni JA, Gordon MK, Sinko PJ.

Biomaterials. 2010 Feb;31(5):964-74. doi: 10.1016/j.biomaterials.2009.10.010. Epub 2009 Oct 22.

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