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Items: 1 to 20 of 149

1.

LGP2 downregulates interferon production during infection with seasonal human influenza A viruses that activate interferon regulatory factor 3.

Malur M, Gale M Jr, Krug RM.

J Virol. 2012 Oct;86(19):10733-8. doi: 10.1128/JVI.00510-12. Epub 2012 Jul 25.

2.

Role of N Terminus-Truncated NS1 Proteins of Influenza A Virus in Inhibiting IRF3 Activation.

Kuo RL, Li LH, Lin SJ, Li ZH, Chen GW, Chang CK, Wang YR, Tam EH, Gong YN, Krug RM, Shih SR.

J Virol. 2016 Apr 14;90(9):4696-4705. doi: 10.1128/JVI.02843-15. Print 2016 May.

3.

Activation of the interferon induction cascade by influenza a viruses requires viral RNA synthesis and nuclear export.

Killip MJ, Smith M, Jackson D, Randall RE.

J Virol. 2014 Apr;88(8):3942-52. doi: 10.1128/JVI.03109-13. Epub 2014 Jan 29.

4.

RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression.

Mäkelä SM, Österlund P, Westenius V, Latvala S, Diamond MS, Gale M Jr, Julkunen I.

J Virol. 2015 Dec;89(23):12014-25. doi: 10.1128/JVI.01576-15. Epub 2015 Sep 16.

5.

Multiple anti-interferon actions of the influenza A virus NS1 protein.

Kochs G, García-Sastre A, Martínez-Sobrido L.

J Virol. 2007 Jul;81(13):7011-21. Epub 2007 Apr 18.

6.

Influenza A virus strains that circulate in humans differ in the ability of their NS1 proteins to block the activation of IRF3 and interferon-β transcription.

Kuo RL, Zhao C, Malur M, Krug RM.

Virology. 2010 Dec 20;408(2):146-58. doi: 10.1016/j.virol.2010.09.012. Epub 2010 Oct 8.

7.

NS1 Protein Mutation I64T Affects Interferon Responses and Virulence of Circulating H3N2 Human Influenza A Viruses.

DeDiego ML, Nogales A, Lambert-Emo K, Martinez-Sobrido L, Topham DJ.

J Virol. 2016 Oct 14;90(21):9693-9711. Print 2016 Nov 1.

8.

Influenza virus non-structural protein 1 (NS1) disrupts interferon signaling.

Jia D, Rahbar R, Chan RW, Lee SM, Chan MC, Wang BX, Baker DP, Sun B, Peiris JS, Nicholls JM, Fish EN.

PLoS One. 2010 Nov 10;5(11):e13927. doi: 10.1371/journal.pone.0013927.

9.

LGP2 is a positive regulator of RIG-I- and MDA5-mediated antiviral responses.

Satoh T, Kato H, Kumagai Y, Yoneyama M, Sato S, Matsushita K, Tsujimura T, Fujita T, Akira S, Takeuchi O.

Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1512-7. doi: 10.1073/pnas.0912986107. Epub 2010 Jan 8.

10.

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

Rajsbaum R, Albrecht RA, Wang MK, Maharaj NP, Versteeg GA, Nistal-Villán E, García-Sastre A, Gack MU.

PLoS Pathog. 2012;8(11):e1003059. doi: 10.1371/journal.ppat.1003059. Epub 2012 Nov 29.

11.

Influenza A(H1N1)pdm09 virus suppresses RIG-I initiated innate antiviral responses in the human lung.

Wu W, Zhang W, Booth JL, Metcalf JP.

PLoS One. 2012;7(11):e49856. doi: 10.1371/journal.pone.0049856. Epub 2012 Nov 21.

12.

Activation of type I and III interferon signalling pathways occurs in lung epithelial cells infected with low pathogenic avian influenza viruses.

Sutejo R, Yeo DS, Myaing MZ, Hui C, Xia J, Ko D, Cheung PC, Tan BH, Sugrue RJ.

PLoS One. 2012;7(3):e33732. doi: 10.1371/journal.pone.0033732. Epub 2012 Mar 21.

13.

Differential Delivery of Genomic Double-Stranded RNA Causes Reovirus Strain-Specific Differences in Interferon Regulatory Factor 3 Activation.

Stuart JD, Holm GH, Boehme KW.

J Virol. 2018 Apr 13;92(9). pii: e01947-17. doi: 10.1128/JVI.01947-17. Print 2018 May 1.

PMID:
29437975
14.

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells.

Deddouche S, Goubau D, Rehwinkel J, Chakravarty P, Begum S, Maillard PV, Borg A, Matthews N, Feng Q, van Kuppeveld FJ, Reis e Sousa C.

Elife. 2014 Feb 18;3:e01535. doi: 10.7554/eLife.01535.

15.

The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells.

Haye K, Burmakina S, Moran T, García-Sastre A, Fernandez-Sesma A.

J Virol. 2009 Jul;83(13):6849-62. doi: 10.1128/JVI.02323-08. Epub 2009 Apr 29.

16.

Incoming influenza A virus evades early host recognition, while influenza B virus induces interferon expression directly upon entry.

Österlund P, Strengell M, Sarin LP, Poranen MM, Fagerlund R, Melén K, Julkunen I.

J Virol. 2012 Oct;86(20):11183-93. Epub 2012 Aug 1.

17.

Herpes simplex virus 1 serine/threonine kinase US3 hyperphosphorylates IRF3 and inhibits beta interferon production.

Wang S, Wang K, Lin R, Zheng C.

J Virol. 2013 Dec;87(23):12814-27. doi: 10.1128/JVI.02355-13. Epub 2013 Sep 18.

18.

Generation and characterization of interferon-lambda 1-resistant H1N1 influenza A viruses.

Ilyushina NA, Lugovtsev VY, Samsonova AP, Sheikh FG, Bovin NV, Donnelly RP.

PLoS One. 2017 Jul 27;12(7):e0181999. doi: 10.1371/journal.pone.0181999. eCollection 2017.

19.

The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.

Rothenfusser S, Goutagny N, DiPerna G, Gong M, Monks BG, Schoenemeyer A, Yamamoto M, Akira S, Fitzgerald KA.

J Immunol. 2005 Oct 15;175(8):5260-8.

20.

The PB2 subunit of the influenza virus RNA polymerase affects virulence by interacting with the mitochondrial antiviral signaling protein and inhibiting expression of beta interferon.

Graef KM, Vreede FT, Lau YF, McCall AW, Carr SM, Subbarao K, Fodor E.

J Virol. 2010 Sep;84(17):8433-45. doi: 10.1128/JVI.00879-10. Epub 2010 Jun 10.

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