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Items: 1 to 20 of 110

1.

SnoN regulates mammary gland alveologenesis and onset of lactation by promoting prolactin/Stat5 signaling.

Jahchan NS, Wang D, Bissell MJ, Luo K.

Development. 2012 Sep;139(17):3147-56. doi: 10.1242/dev.079616.

PMID:
22833129
2.

Autocrine prolactin induced by the Pten-Akt pathway is required for lactation initiation and provides a direct link between the Akt and Stat5 pathways.

Chen CC, Stairs DB, Boxer RB, Belka GK, Horseman ND, Alvarez JV, Chodosh LA.

Genes Dev. 2012 Oct 1;26(19):2154-68. doi: 10.1101/gad.197343.112.

PMID:
23028142
3.

Transforming growth factor-beta regulator SnoN modulates mammary gland branching morphogenesis, postlactational involution, and mammary tumorigenesis.

Jahchan NS, You YH, Muller WJ, Luo K.

Cancer Res. 2010 May 15;70(10):4204-13. doi: 10.1158/0008-5472.CAN-10-0135.

PMID:
20460516
4.

Lactation failure in Src knockout mice is due to impaired secretory activation.

Watkin H, Richert MM, Lewis A, Terrell K, McManaman JP, Anderson SM.

BMC Dev Biol. 2008 Jan 23;8:6. doi: 10.1186/1471-213X-8-6.

PMID:
18215306
5.

Impaired alveologenesis and maintenance of secretory mammary epithelial cells in Jak2 conditional knockout mice.

Wagner KU, Krempler A, Triplett AA, Qi Y, George NM, Zhu J, Rui H.

Mol Cell Biol. 2004 Jun;24(12):5510-20.

PMID:
15169911
6.

Prolactin regulates ZNT2 expression through the JAK2/STAT5 signaling pathway in mammary cells.

Qian L, Lopez V, Seo YA, Kelleher SL.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C369-77. doi: 10.1152/ajpcell.00589.2008.

PMID:
19494234
7.

Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation.

Ke Y, Lesperance J, Zhang EE, Bard-Chapeau EA, Oshima RG, Muller WJ, Feng GS.

J Biol Chem. 2006 Nov 10;281(45):34374-80.

PMID:
16959766
8.

Impaired differentiation and lactational failure of Erbb4-deficient mammary glands identify ERBB4 as an obligate mediator of STAT5.

Long W, Wagner KU, Lloyd KC, Binart N, Shillingford JM, Hennighausen L, Jones FE.

Development. 2003 Nov;130(21):5257-68.

PMID:
12954715
9.

Smad signaling antagonizes STAT5-mediated gene transcription and mammary epithelial cell differentiation.

Cocolakis E, Dai M, Drevet L, Ho J, Haines E, Ali S, Lebrun JJ.

J Biol Chem. 2008 Jan 18;283(3):1293-307.

PMID:
18024957
10.
12.

Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation.

Naylor MJ, Li N, Cheung J, Lowe ET, Lambert E, Marlow R, Wang P, Schatzmann F, Wintermantel T, Sch├╝etz G, Clarke AR, Mueller U, Hynes NE, Streuli CH.

J Cell Biol. 2005 Nov 21;171(4):717-28.

PMID:
16301336
13.

Prolactin, growth hormone, and epidermal growth factor activate Stat5 in different compartments of mammary tissue and exert different and overlapping developmental effects.

Gallego MI, Binart N, Robinson GW, Okagaki R, Coschigano KT, Perry J, Kopchick JJ, Oka T, Kelly PA, Hennighausen L.

Dev Biol. 2001 Jan 1;229(1):163-75.

PMID:
11133161
14.

Perturbation of beta1-integrin function in involuting mammary gland results in premature dedifferentiation of secretory epithelial cells.

Faraldo MM, Deugnier MA, Tlouzeau S, Thiery JP, Glukhova MA.

Mol Biol Cell. 2002 Oct;13(10):3521-31.

PMID:
12388754
15.

Akt is required for Stat5 activation and mammary differentiation.

Chen CC, Boxer RB, Stairs DB, Portocarrero CP, Horton RH, Alvarez JV, Birnbaum MJ, Chodosh LA.

Breast Cancer Res. 2010;12(5):R72. doi: 10.1186/bcr2640.

PMID:
20849614
16.

The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development.

Clarkson RW, Boland MP, Kritikou EA, Lee JM, Freeman TC, Tiffen PG, Watson CJ.

Mol Endocrinol. 2006 Mar;20(3):675-85.

PMID:
16293640
17.

Protein tyrosine phosphatase 1B restrains mammary alveologenesis and secretory differentiation.

Milani ES, Brinkhaus H, Dueggeli R, Klebba I, Mueller U, Stadler M, Kohler H, Smalley MJ, Bentires-Alj M.

Development. 2013 Jan 1;140(1):117-25. doi: 10.1242/dev.082941.

PMID:
23154416
18.

PIKE-A is required for prolactin-mediated STAT5a activation in mammary gland development.

Chan CB, Liu X, Ensslin MA, Dillehay DL, Ormandy CJ, Sohn P, Serra R, Ye K.

EMBO J. 2010 Mar 3;29(5):956-68. doi: 10.1038/emboj.2009.406.

PMID:
20075866
19.

Prolactin and transforming growth factor-beta signaling exert opposing effects on mammary gland morphogenesis, involution, and the Akt-forkhead pathway.

Bailey JP, Nieport KM, Herbst MP, Srivastava S, Serra RA, Horseman ND.

Mol Endocrinol. 2004 May;18(5):1171-84.

PMID:
14963111
20.

Prolactin-mediated regulation of lipid biosynthesis genes in vivo in the lactating mammary epithelial cell.

Rudolph MC, Russell TD, Webb P, Neville MC, Anderson SM.

Am J Physiol Endocrinol Metab. 2011 Jun;300(6):E1059-68. doi: 10.1152/ajpendo.00083.2011.

PMID:
21467304
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