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Items: 1 to 20 of 151

1.

Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100.

Maczuga P, Koornneef A, Borel F, Petry H, van Deventer S, Ritsema T, Konstantinova P.

BMC Biotechnol. 2012 Jul 24;12:42. doi: 10.1186/1472-6750-12-42.

2.

Expression of short hairpin RNAs using the compact architecture of retroviral microRNA genes.

Burke JM, Kincaid RP, Aloisio F, Welch N, Sullivan CS.

Nucleic Acids Res. 2017 Sep 29;45(17):e154. doi: 10.1093/nar/gkx653.

3.

Embedding siRNA sequences targeting apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy.

Maczuga P, Lubelski J, van Logtenstein R, Borel F, Blits B, Fakkert E, Costessi A, Butler D, van Deventer S, Petry H, Koornneef A, Konstantinova P.

Mol Ther. 2013 Jan;21(1):217-27. doi: 10.1038/mt.2012.160. Epub 2012 Oct 23.

4.

A quick and efficient approach for gene silencing by using triple putative microRNA-based short hairpin RNAs.

Shan ZX, Lin QX, Yang M, Deng CY, Kuang SJ, Zhou ZL, Xiao DZ, Liu XY, Lin SG, Yu XY.

Mol Cell Biochem. 2009 Mar;323(1-2):81-9. doi: 10.1007/s11010-008-9966-3. Epub 2008 Nov 27.

PMID:
19037714
5.

Schistosoma mansoni U6 gene promoter-driven short hairpin RNA induces RNA interference in human fibrosarcoma cells and schistosomules.

Ayuk MA, Suttiprapa S, Rinaldi G, Mann VH, Lee CM, Brindley PJ.

Int J Parasitol. 2011 Jun;41(7):783-9. doi: 10.1016/j.ijpara.2011.02.004. Epub 2011 Apr 9.

6.

Poly(U) and polyadenylation termination signals are interchangeable for terminating the expression of shRNA from a pol II promoter.

Song J, Pang S, Lu Y, Chiu R.

Biochem Biophys Res Commun. 2004 Oct 15;323(2):573-8.

PMID:
15369789
8.

Quantitative evaluation of first, second, and third generation hairpin systems reveals the limit of mammalian vector-based RNAi.

Watanabe C, Cuellar TL, Haley B.

RNA Biol. 2016;13(1):25-33. doi: 10.1080/15476286.2015.1128062.

9.

miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction.

Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, Williams DA.

Mol Ther. 2015 Sep;23(9):1465-74. doi: 10.1038/mt.2015.113. Epub 2015 Jun 17.

10.

Optimization of a microRNA expression vector for function analysis of microRNA.

Furukawa N, Sakurai F, Katayama K, Seki N, Kawabata K, Mizuguchi H.

J Control Release. 2011 Feb 28;150(1):94-101. doi: 10.1016/j.jconrel.2010.12.001. Epub 2010 Dec 10.

PMID:
21146569
11.

A hybrid CMV-H1 construct improves efficiency of PEI-delivered shRNA in the mouse brain.

Hassani Z, Fran├žois JC, Alfama G, Dubois GM, Paris M, Giovannangeli C, Demeneix BA.

Nucleic Acids Res. 2007;35(9):e65. Epub 2007 Apr 10.

12.

Expression of shRNA from a tissue-specific pol II promoter is an effective and safe RNAi therapeutic.

Giering JC, Grimm D, Storm TA, Kay MA.

Mol Ther. 2008 Sep;16(9):1630-6. doi: 10.1038/mt.2008.144. Epub 2008 Jul 29.

13.

Production of transgenic pigs that express porcine endogenous retrovirus small interfering RNAs.

Ramsoondar J, Vaught T, Ball S, Mendicino M, Monahan J, Jobst P, Vance A, Duncan J, Wells K, Ayares D.

Xenotransplantation. 2009 May-Jun;16(3):164-80. doi: 10.1111/j.1399-3089.2009.00525.x.

PMID:
19566656
14.

Characterisation and comparison of the chicken H1 RNA polymerase III promoter for short hairpin RNA expression.

Cummins DM, Tyack SG, Doran TJ.

Biochem Biophys Res Commun. 2011 Dec 9;416(1-2):194-8. doi: 10.1016/j.bbrc.2011.11.024. Epub 2011 Nov 10.

PMID:
22093828
15.

Hairpin RNAs derived from RNA polymerase II and polymerase III promoter-directed transgenes are processed differently in plants.

Wang MB, Helliwell CA, Wu LM, Waterhouse PM, Peacock WJ, Dennis ES.

RNA. 2008 May;14(5):903-13. doi: 10.1261/rna.760908. Epub 2008 Mar 26.

16.

Comparison of chicken 7SK and U6 RNA polymerase III promoters for short hairpin RNA expression.

Bannister SC, Wise TG, Cahill DM, Doran TJ.

BMC Biotechnol. 2007 Nov 19;7:79.

17.

Identification and characterization of buffalo 7SK and U6 pol III promoters and application for expression of short hairpin RNAs.

Zhang X, Liu Q, Luo C, Deng Y, Cui K, Shi D.

Int J Mol Sci. 2014 Feb 14;15(2):2596-607. doi: 10.3390/ijms15022596.

18.

Construction, modification and evaluation of apolipoprotein A-I promoter-driven shRNA expression vectors against hTERT.

Ren X, Ma Y, Xu M, Chen T, Zhang Z, Zhang Y.

Plasmid. 2011 Jan;65(1):42-50. doi: 10.1016/j.plasmid.2010.11.001. Epub 2010 Nov 16.

PMID:
21087625
19.

Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters.

Lo HL, Chang T, Yam P, Marcovecchio PM, Li S, Zaia JA, Yee JK.

Gene Ther. 2007 Nov;14(21):1503-12. Epub 2007 Sep 6.

PMID:
17805304
20.

Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs.

Lebbink RJ, Lowe M, Chan T, Khine H, Wang X, McManus MT.

PLoS One. 2011;6(10):e26213. doi: 10.1371/journal.pone.0026213. Epub 2011 Oct 21.

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