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Cerulein hyperstimulation decreases AMP-activated protein kinase levels at the site of maximal zymogen activation.

Shugrue CA, Alexandre M, Diaz de Villalvilla A, Kolodecik TR, Young LH, Gorelick FS, Thrower EC.

Am J Physiol Gastrointest Liver Physiol. 2012 Sep 15;303(6):G723-32. doi: 10.1152/ajpgi.00082.2012. Epub 2012 Jul 19.


Effect of the AMP-kinase modulators AICAR, metformin and compound C on insulin secretion of INS-1E rat insulinoma cells under standard cell culture conditions.

Langelueddecke C, Jakab M, Ketterl N, Lehner L, Hufnagl C, Schmidt S, Geibel JP, Fuerst J, Ritter M.

Cell Physiol Biochem. 2012;29(1-2):75-86. doi: 10.1159/000337589. Epub 2012 Mar 1.


AMP-activated protein kinase inhibits alkaline pH- and PKA-induced apical vacuolar H+-ATPase accumulation in epididymal clear cells.

Hallows KR, Alzamora R, Li H, Gong F, Smolak C, Neumann D, Pastor-Soler NM.

Am J Physiol Cell Physiol. 2009 Apr;296(4):C672-81. doi: 10.1152/ajpcell.00004.2009. Epub 2009 Feb 11.


Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells.

Kolodecik TR, Shugrue CA, Thrower EC, Levin LR, Buck J, Gorelick FS.

PLoS One. 2012;7(7):e41320. doi: 10.1371/journal.pone.0041320. Epub 2012 Jul 23.


AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass.

Shah M, Kola B, Bataveljic A, Arnett TR, Viollet B, Saxon L, Korbonits M, Chenu C.

Bone. 2010 Aug;47(2):309-19. doi: 10.1016/j.bone.2010.04.596. Epub 2010 Apr 24.


Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats.

Bhoomagoud M, Jung T, Atladottir J, Kolodecik TR, Shugrue C, Chaudhuri A, Thrower EC, Gorelick FS.

Gastroenterology. 2009 Sep;137(3):1083-92. doi: 10.1053/j.gastro.2009.05.041. Epub 2009 May 18.


Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR-induced AMPK activation.

Anthony NM, Gaidhu MP, Ceddia RB.

Obesity (Silver Spring). 2009 Jul;17(7):1312-7. doi: 10.1038/oby.2008.645. Epub 2009 Feb 12.


AICAR and Metformin Exert AMPK-dependent Effects on INS-1E Pancreatic β-cell Apoptosis via Differential Downstream Mechanisms.

Dai YL, Huang SL, Leng Y.

Int J Biol Sci. 2015 Sep 14;11(11):1272-80. doi: 10.7150/ijbs.12108. eCollection 2015.


Vacuolar ATPase regulates zymogen activation in pancreatic acini.

Waterford SD, Kolodecik TR, Thrower EC, Gorelick FS.

J Biol Chem. 2005 Feb 18;280(7):5430-4. Epub 2004 Dec 6.


Antiplatelet effect of AMP-activated protein kinase activator and its potentiation by the phosphodiesterase inhibitor dipyridamole.

Liu Y, Oh SJ, Chang KH, Kim YG, Lee MY.

Biochem Pharmacol. 2013 Oct 1;86(7):914-25. doi: 10.1016/j.bcp.2013.07.009. Epub 2013 Jul 19.


Metformin-stimulated AMPK-α1 promotes microvascular repair in acute lung injury.

Jian MY, Alexeyev MF, Wolkowicz PE, Zmijewski JW, Creighton JR.

Am J Physiol Lung Cell Mol Physiol. 2013 Dec;305(11):L844-55. doi: 10.1152/ajplung.00173.2013. Epub 2013 Oct 4.


AMPK inhibition blocks ROS-NFκB signaling and attenuates endotoxemia-induced liver injury.

Guo Y, Zhang Y, Hong K, Luo F, Gu Q, Lu N, Bai A.

PLoS One. 2014 Jan 24;9(1):e86881. doi: 10.1371/journal.pone.0086881. eCollection 2014.


Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells.

Benziane B, Björnholm M, Pirkmajer S, Austin RL, Kotova O, Viollet B, Zierath JR, Chibalin AV.

J Biol Chem. 2012 Jul 6;287(28):23451-63. doi: 10.1074/jbc.M111.331926. Epub 2012 May 18.


Activation of AMP-activated protein kinase may not be involved in AICAR- and metformin-mediated meiotic arrest in bovine denuded and cumulus-enclosed oocytes in vitro.

Bilodeau-Goeseels S, Panich PL, Kastelic JP.

Zygote. 2011 May;19(2):97-106. doi: 10.1017/S0967199410000195. Epub 2010 Jun 23.


A pharmacological activator of AMP-activated protein kinase protects hypoxic neurons in a concentration-dependent manner.

Zhang X, Gao R, Li J, Qi Y, Song X, Zhao L, Wang H, Pu Y, Xu K, Li J.

Neurochem Res. 2010 Aug;35(8):1281-9. doi: 10.1007/s11064-010-0186-3. Epub 2010 May 20.


Activation of AMP-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside in the muscle microcirculation increases nitric oxide synthesis and microvascular perfusion.

Bradley EA, Eringa EC, Stehouwer CD, Korstjens I, van Nieuw Amerongen GP, Musters R, Sipkema P, Clark MG, Rattigan S.

Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1137-42. doi: 10.1161/ATVBAHA.110.204404. Epub 2010 Mar 11.


Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction.

Paiva MA, Gonçalves LM, Providência LA, Davidson SM, Yellon DM, Mocanu MM.

Cardiovasc Drugs Ther. 2010 Feb;24(1):25-32. doi: 10.1007/s10557-010-6222-3.


AMP-activated protein kinase phosphorylates transcription factors of the CREB family.

Thomson DM, Herway ST, Fillmore N, Kim H, Brown JD, Barrow JR, Winder WW.

J Appl Physiol (1985). 2008 Feb;104(2):429-38. Epub 2007 Dec 6.


Traumatic brain injury decreases AMP-activated protein kinase activity and pharmacological enhancement of its activity improves cognitive outcome.

Hill JL, Kobori N, Zhao J, Rozas NS, Hylin MJ, Moore AN, Dash PK.

J Neurochem. 2016 Oct;139(1):106-19. doi: 10.1111/jnc.13726. Epub 2016 Aug 1.


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