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Items: 1 to 20 of 114

1.

Protein interactions: mapping interactome networks to support drug target discovery and selection.

De Las Rivas J, Prieto C.

Methods Mol Biol. 2012;910:279-96. doi: 10.1007/978-1-61779-965-5_12. Review.

PMID:
22821600
2.

Interaction networks: from protein functions to drug discovery. A review.

Chautard E, Thierry-Mieg N, Ricard-Blum S.

Pathol Biol (Paris). 2009 Jun;57(4):324-33. doi: 10.1016/j.patbio.2008.10.004. Epub 2008 Dec 13. Review.

PMID:
19070972
3.

Databases of protein-protein interactions and their use in drug discovery.

Fuentes G, Oyarzabal J, Rojas AM.

Curr Opin Drug Discov Devel. 2009 May;12(3):358-66. Review.

PMID:
19396737
4.

Predicting the interactome of Xanthomonas oryzae pathovar oryzae for target selection and DB service.

Kim JG, Park D, Kim BC, Cho SW, Kim YT, Park YJ, Cho HJ, Park H, Kim KB, Yoon KO, Park SJ, Lee BM, Bhak J.

BMC Bioinformatics. 2008 Jan 24;9:41. doi: 10.1186/1471-2105-9-41.

5.

Charting plant interactomes: possibilities and challenges.

Morsy M, Gouthu S, Orchard S, Thorneycroft D, Harper JF, Mittler R, Cushman JC.

Trends Plant Sci. 2008 Apr;13(4):183-91. doi: 10.1016/j.tplants.2008.01.006. Epub 2008 Mar 7. Review.

PMID:
18329319
6.

From protein interaction networks to novel therapeutic strategies.

Jaeger S, Aloy P.

IUBMB Life. 2012 Jun;64(6):529-37. doi: 10.1002/iub.1040. Epub 2012 May 9. Review.

7.

Interactome mapping for analysis of complex phenotypes: insights from benchmarking binary interaction assays.

Braun P.

Proteomics. 2012 May;12(10):1499-518. doi: 10.1002/pmic.201100598. Review.

PMID:
22589225
8.

An integrative in silico approach for discovering candidates for drug-targetable protein-protein interactions in interactome data.

Sugaya N, Ikeda K, Tashiro T, Takeda S, Otomo J, Ishida Y, Shiratori A, Toyoda A, Noguchi H, Takeda T, Kuhara S, Sakaki Y, Iwayanagi T.

BMC Pharmacol. 2007 Aug 20;7:10.

9.

Mycobacterium tuberculosis interactome analysis unravels potential pathways to drug resistance.

Raman K, Chandra N.

BMC Microbiol. 2008 Dec 23;8:234. doi: 10.1186/1471-2180-8-234.

10.

Structural systems pharmacology: the role of 3D structures in next-generation drug development.

Duran-Frigola M, Mosca R, Aloy P.

Chem Biol. 2013 May 23;20(5):674-84. doi: 10.1016/j.chembiol.2013.03.004. Review.

11.

DTome: a web-based tool for drug-target interactome construction.

Sun J, Wu Y, Xu H, Zhao Z.

BMC Bioinformatics. 2012 Jun 11;13 Suppl 9:S7. doi: 10.1186/1471-2105-13-S9-S7.

12.

Protein-protein interactions: network analysis and applications in drug discovery.

Bultinck J, Lievens S, Tavernier J.

Curr Pharm Des. 2012;18(30):4619-29. Review.

PMID:
22650261
13.

Physical and in silico approaches identify DNA-PK in a Tax DNA-damage response interactome.

Ramadan E, Ward M, Guo X, Durkin SS, Sawyer A, Vilela M, Osgood C, Pothen A, Semmes OJ.

Retrovirology. 2008 Oct 15;5:92. doi: 10.1186/1742-4690-5-92.

14.

Network-based characterization of drug-regulated genes, drug targets, and toxicity.

Kotlyar M, Fortney K, Jurisica I.

Methods. 2012 Aug;57(4):499-507. doi: 10.1016/j.ymeth.2012.06.003. Epub 2012 Jun 27. Review.

15.

Identification of SRC as a potent drug target for asthma, using an integrative approach of protein interactome analysis and in silico drug discovery.

Randhawa V, Bagler G.

OMICS. 2012 Oct;16(10):513-26. doi: 10.1089/omi.2011.0160. Epub 2012 Jul 9.

PMID:
22775150
16.

Drug-target interaction prediction by random walk on the heterogeneous network.

Chen X, Liu MX, Yan GY.

Mol Biosyst. 2012 Jul 6;8(7):1970-8. doi: 10.1039/c2mb00002d. Epub 2012 Apr 26.

PMID:
22538619
17.

The topology of drug-target interaction networks: implicit dependence on drug properties and target families.

Mestres J, Gregori-Puigjané E, Valverde S, Solé RV.

Mol Biosyst. 2009 Sep;5(9):1051-7. doi: 10.1039/b905821b. Epub 2009 Jul 8.

PMID:
19668871
18.

Protein fragment complementation strategies for biochemical network mapping.

Michnick SW.

Curr Opin Biotechnol. 2003 Dec;14(6):610-7. Review.

PMID:
14662390
19.

Dr. PIAS 2.0: an update of a database of predicted druggable protein-protein interactions.

Sugaya N, Kanai S, Furuya T.

Database (Oxford). 2012 Oct 10;2012:bas034. doi: 10.1093/database/bas034. Print 2012.

20.

Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins.

Cho YR, Zhang A.

BMC Bioinformatics. 2010 Apr 29;11 Suppl 3:S3. doi: 10.1186/1471-2105-11-S3-S3.

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