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Performance of combination drug and hygroscopic excipient submicrometer particles from a softmist inhaler in a characteristic model of the airways.

Longest PW, Tian G, Li X, Son YJ, Hindle M.

Ann Biomed Eng. 2012 Dec;40(12):2596-610. doi: 10.1007/s10439-012-0616-2. Epub 2012 Jul 21.


Targeting aerosol deposition to and within the lung airways using excipient enhanced growth.

Tian G, Longest PW, Li X, Hindle M.

J Aerosol Med Pulm Drug Deliv. 2013 Oct;26(5):248-65. doi: 10.1089/jamp.2012.0997. Epub 2013 Jan 3.


Characterization of respiratory drug delivery with enhanced condensational growth using an individual path model of the entire tracheobronchial airways.

Tian G, Longest PW, Su G, Hindle M.

Ann Biomed Eng. 2011 Mar;39(3):1136-53. doi: 10.1007/s10439-010-0223-z. Epub 2010 Dec 9.


Validating CFD Predictions of Pharmaceutical Aerosol Deposition with In Vivo Data.

Tian G, Hindle M, Lee S, Longest PW.

Pharm Res. 2015 Oct;32(10):3170-87. doi: 10.1007/s11095-015-1695-1. Epub 2015 May 6.


Condensational growth of combination drug-excipient submicrometer particles for targeted high-efficiency pulmonary delivery: evaluation of formulation and delivery device.

Hindle M, Longest PW.

J Pharm Pharmacol. 2012 Sep;64(9):1254-63. doi: 10.1111/j.2042-7158.2012.01476.x. Epub 2012 Feb 21.


Evaluation of enhanced condensational growth (ECG) for controlled respiratory drug delivery in a mouth-throat and upper tracheobronchial model.

Hindle M, Longest PW.

Pharm Res. 2010 Sep;27(9):1800-11. doi: 10.1007/s11095-010-0165-z. Epub 2010 May 8.


Efficient Nose-to-Lung (N2L) Aerosol Delivery with a Dry Powder Inhaler.

Longest PW, Golshahi L, Behara SR, Tian G, Farkas DR, Hindle M.

J Aerosol Med Pulm Drug Deliv. 2015 Jun;28(3):189-201. doi: 10.1089/jamp.2014.1158. Epub 2014 Sep 5.


Targeted Lung Delivery of Nasally Administered Aerosols.

Tian G, Hindle M, Longest PW.

Aerosol Sci Technol. 2014;48(4):434-449.


The use of condensational growth methods for efficient drug delivery to the lungs during noninvasive ventilation high flow therapy.

Golshahi L, Tian G, Azimi M, Son YJ, Walenga R, Longest PW, Hindle M.

Pharm Res. 2013 Nov;30(11):2917-30. doi: 10.1007/s11095-013-1123-3. Epub 2013 Jun 26.


Current Inhalers Deliver Very Small Doses to the Lower Tracheobronchial Airways: Assessment of Healthy and Constricted Lungs.

Walenga RL, Longest PW.

J Pharm Sci. 2016 Jan;105(1):147-59. doi: 10.1016/j.xphs.2015.11.027. Epub 2016 Jan 13.


Evaluation and modification of commercial dry powder inhalers for the aerosolization of a submicrometer excipient enhanced growth (EEG) formulation.

Son YJ, Longest PW, Tian G, Hindle M.

Eur J Pharm Sci. 2013 Jun 14;49(3):390-9. doi: 10.1016/j.ejps.2013.04.011. Epub 2013 Apr 19.


Development of characteristic upper tracheobronchial airway models for testing pharmaceutical aerosol delivery.

Walenga RL, Tian G, Longest PW.

J Biomech Eng. 2013 Sep;135(9):91010. doi: 10.1115/1.4024630.


Improving the lung delivery of nasally administered aerosols during noninvasive ventilation-an application of enhanced condensational growth (ECG).

Longest PW, Tian G, Hindle M.

J Aerosol Med Pulm Drug Deliv. 2011 Apr;24(2):103-18. doi: 10.1089/jamp.2010.0849. Epub 2011 Mar 16.


Comparing MDI and DPI aerosol deposition using in vitro experiments and a new stochastic individual path (SIP) model of the conducting airways.

Longest PW, Tian G, Walenga RL, Hindle M.

Pharm Res. 2012 Jun;29(6):1670-88. doi: 10.1007/s11095-012-0691-y.


Hygroscopic aerosol deposition in the human upper respiratory tract under various thermo-humidity conditions.

Xi J, Kim J, Si XA, Zhou Y.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2013;48(14):1790-805. doi: 10.1080/10934529.2013.823333.


Validating Whole-Airway CFD Predictions of DPI Aerosol Deposition at Multiple Flow Rates.

Longest PW, Tian G, Khajeh-Hosseini-Dalasm N, Hindle M.

J Aerosol Med Pulm Drug Deliv. 2016 Dec;29(6):461-481. Epub 2016 Apr 15.


In silico models of aerosol delivery to the respiratory tract - development and applications.

Longest PW, Holbrook LT.

Adv Drug Deliv Rev. 2012 Mar 30;64(4):296-311. doi: 10.1016/j.addr.2011.05.009. Epub 2011 May 27. Review.

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