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Items: 1 to 20 of 100

1.

The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis.

Li J, McQuade T, Siemer AB, Napetschnig J, Moriwaki K, Hsiao YS, Damko E, Moquin D, Walz T, McDermott A, Chan FK, Wu H.

Cell. 2012 Jul 20;150(2):339-50. doi: 10.1016/j.cell.2012.06.019.

2.

Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis.

Wu XN, Yang ZH, Wang XK, Zhang Y, Wan H, Song Y, Chen X, Shao J, Han J.

Cell Death Differ. 2014 Nov;21(11):1709-20. doi: 10.1038/cdd.2014.77. Epub 2014 Jun 6.

3.

Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis.

McQuade T, Cho Y, Chan FK.

Biochem J. 2013 Dec 15;456(3):409-15. doi: 10.1042/BJ20130860.

4.

CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis.

Moquin DM, McQuade T, Chan FK.

PLoS One. 2013 Oct 2;8(10):e76841. doi: 10.1371/journal.pone.0076841. eCollection 2013.

5.

RIP1 and RIP3 complex regulates radiation-induced programmed necrosis in glioblastoma.

Das A, McDonald DG, Dixon-Mah YN, Jacqmin DJ, Samant VN, Vandergrift WA 3rd, Lindhorst SM, Cachia D, Varma AK, Vanek KN, Banik NL, Jenrette JM 3rd, Raizer JJ, Giglio P, Patel SJ.

Tumour Biol. 2016 Jun;37(6):7525-34. doi: 10.1007/s13277-015-4621-6. Epub 2015 Dec 18.

PMID:
26684801
6.

Toll-like receptor 3-mediated necrosis via TRIF, RIP3, and MLKL.

Kaiser WJ, Sridharan H, Huang C, Mandal P, Upton JW, Gough PJ, Sehon CA, Marquis RW, Bertin J, Mocarski ES.

J Biol Chem. 2013 Oct 25;288(43):31268-79. doi: 10.1074/jbc.M113.462341. Epub 2013 Sep 9.

7.

Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling.

Chen W, Zhou Z, Li L, Zhong CQ, Zheng X, Wu X, Zhang Y, Ma H, Huang D, Li W, Xia Z, Han J.

J Biol Chem. 2013 Jun 7;288(23):16247-61. doi: 10.1074/jbc.M112.435545. Epub 2013 Apr 23.

8.

Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation.

Lu B, Gong X, Wang ZQ, Ding Y, Wang C, Luo TF, Piao MH, Meng FK, Chi GF, Luo YN, Ge PF.

Acta Pharmacol Sin. 2017 Nov;38(11):1543-1553. doi: 10.1038/aps.2017.112. Epub 2017 Aug 17.

PMID:
28816233
9.

Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.

Cho YS, Challa S, Moquin D, Genga R, Ray TD, Guildford M, Chan FK.

Cell. 2009 Jun 12;137(6):1112-23. doi: 10.1016/j.cell.2009.05.037.

10.

Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination.

de Almagro MC, Goncharov T, Newton K, Vucic D.

Cell Death Dis. 2015 Jun 25;6:e1800. doi: 10.1038/cddis.2015.158.

11.

The role of the kinases RIP1 and RIP3 in TNF-induced necrosis.

Vandenabeele P, Declercq W, Van Herreweghe F, Vanden Berghe T.

Sci Signal. 2010 Mar 30;3(115):re4. doi: 10.1126/scisignal.3115re4. Review.

PMID:
20354226
12.

Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases.

Thapa RJ, Nogusa S, Chen P, Maki JL, Lerro A, Andrake M, Rall GF, Degterev A, Balachandran S.

Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3109-18. doi: 10.1073/pnas.1301218110. Epub 2013 Jul 29.

13.

DAI/ZBP1/DLM-1 complexes with RIP3 to mediate virus-induced programmed necrosis that is targeted by murine cytomegalovirus vIRA.

Upton JW, Kaiser WJ, Mocarski ES.

Cell Host Microbe. 2012 Mar 15;11(3):290-7. doi: 10.1016/j.chom.2012.01.016.

14.

Distinctive roles of receptor-interacting protein kinases 1 and 3 in caspase-independent cell death of L929.

Park SY, Shim JH, Cho YS.

Cell Biochem Funct. 2014 Jan;32(1):62-9. doi: 10.1002/cbf.2972. Epub 2013 Apr 15.

PMID:
23584955
15.

5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma.

Coupienne I, Fettweis G, Rubio N, Agostinis P, Piette J.

Photochem Photobiol Sci. 2011 Dec;10(12):1868-78. doi: 10.1039/c1pp05213f. Epub 2011 Oct 28.

PMID:
22033613
16.

DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB.

Rebsamen M, Heinz LX, Meylan E, Michallet MC, Schroder K, Hofmann K, Vazquez J, Benedict CA, Tschopp J.

EMBO Rep. 2009 Aug;10(8):916-22. doi: 10.1038/embor.2009.109. Epub 2009 Jul 10.

17.

The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression.

Seifert L, Werba G, Tiwari S, Giao Ly NN, Alothman S, Alqunaibit D, Avanzi A, Barilla R, Daley D, Greco SH, Torres-Hernandez A, Pergamo M, Ochi A, Zambirinis CP, Pansari M, Rendon M, Tippens D, Hundeyin M, Mani VR, Hajdu C, Engle D, Miller G.

Nature. 2016 Apr 14;532(7598):245-9. doi: 10.1038/nature17403. Epub 2016 Apr 6.

18.

RIP3: a molecular switch for necrosis and inflammation.

Moriwaki K, Chan FK.

Genes Dev. 2013 Aug 1;27(15):1640-9. doi: 10.1101/gad.223321.113. Review.

19.

Palmitate induces RIP1/RIP3-dependent necrosis via MLKL-mediated pore formation in the plasma membrane of RAW 264.7 cells.

Kim SK, Yun M, Seo G, Lee JY, Lee SB.

Biochem Biophys Res Commun. 2017 Jan 8;482(2):359-365. doi: 10.1016/j.bbrc.2016.11.068. Epub 2016 Nov 14.

PMID:
27856241
20.

Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.

Zhao J, Jitkaew S, Cai Z, Choksi S, Li Q, Luo J, Liu ZG.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5322-7. doi: 10.1073/pnas.1200012109. Epub 2012 Mar 15.

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