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Items: 1 to 20 of 95


Voluntary intravenous self-administration of alcohol detects an interaction between GABAergic manipulation and GABRG1 polymorphism genotype: a pilot study.

Plawecki MH, Wetherill L, Vitvitskiy V, Kosobud A, Zimmermann US, Edenberg HJ, O'Connor S.

Alcohol Clin Exp Res. 2013 Jan;37 Suppl 1:E152-60. doi: 10.1111/j.1530-0277.2012.01885.x. Epub 2012 Jul 20.


Adaptation of Subjective Responses to Alcohol is Affected by an Interaction of GABRA2 Genotype and Recent Drinking.

Kosobud AE, Wetherill L, Plawecki MH, Kareken DA, Liang T, Nurnberger JL, Windisch K, Xuei X, Edenberg HJ, Foroud TM, O'Connor SJ.

Alcohol Clin Exp Res. 2015 Jul;39(7):1148-57. doi: 10.1111/acer.12749. Epub 2015 Jun 19.


A GABRA2 variant is associated with increased stimulation and 'high' following alcohol administration.

Arias AJ, Covault J, Feinn R, Pond T, Yang BZ, Ge W, Oncken C, Kranzler HR.

Alcohol Alcohol. 2014 Jan-Feb;49(1):1-9. doi: 10.1093/alcalc/agt163. Epub 2013 Oct 27.


GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans.

Ittiwut C, Yang BZ, Kranzler HR, Anton RF, Hirunsatit R, Weiss RD, Covault J, Farrer LA, Gelernter J.

Alcohol Clin Exp Res. 2012 Apr;36(4):588-93. doi: 10.1111/j.1530-0277.2011.01637.x. Epub 2011 Sep 15.


Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene.

Covault J, Gelernter J, Jensen K, Anton R, Kranzler HR.

Neuropsychopharmacology. 2008 Mar;33(4):837-48. Epub 2007 May 16.


Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression.

Haughey HM, Ray LA, Finan P, Villanueva R, Niculescu M, Hutchison KE.

Genes Brain Behav. 2008 Jun;7(4):447-54. Epub 2007 Dec 18.


GABRG1 and GABRA2 as independent predictors for alcoholism in two populations.

Enoch MA, Hodgkinson CA, Yuan Q, Albaugh B, Virkkunen M, Goldman D.

Neuropsychopharmacology. 2009 Apr;34(5):1245-54. doi: 10.1038/npp.2008.171. Epub 2008 Sep 24.


Development and pilot validation of computer-assisted self-infusion of ethanol (CASE): a new method to study alcohol self-administration in humans.

Zimmermann US, Mick I, Vitvitskyi V, Plawecki MH, Mann KF, O'Connor S.

Alcohol Clin Exp Res. 2008 Jul;32(7):1321-8. doi: 10.1111/j.1530-0277.2008.00700.x.


A polymorphism in GABRA2 is associated with the medial frontal response to alcohol cues in an fMRI study.

Kareken DA, Liang T, Wetherill L, Dzemidzic M, Bragulat V, Cox C, Talavage T, O'Connor SJ, Foroud T.

Alcohol Clin Exp Res. 2010 Dec;34(12):2169-78. doi: 10.1111/j.1530-0277.2010.01293.x.


Associations of OPRM1 A118G and alcohol sensitivity with intravenous alcohol self-administration in young adults.

Hendershot CS, Claus ED, Ramchandani VA.

Addict Biol. 2016 Jan;21(1):125-35. doi: 10.1111/adb.12165. Epub 2014 Jul 20.


GABRA2 markers moderate the subjective effects of alcohol.

Uhart M, Weerts EM, McCaul ME, Guo X, Yan X, Kranzler HR, Li N, Wand GS.

Addict Biol. 2013 Mar;18(2):357-69. doi: 10.1111/j.1369-1600.2012.00457.x. Epub 2012 Apr 13.


Reduction of alcohol's reinforcing and motivational properties by the positive allosteric modulator of the GABA(B) receptor, BHF177, in alcohol-preferring rats.

Maccioni P, Carai MA, Kaupmann K, Guery S, Froestl W, Leite-Morris KA, Gessa GL, Colombo G.

Alcohol Clin Exp Res. 2009 Oct;33(10):1749-56. doi: 10.1111/j.1530-0277.2009.01012.x. Epub 2009 Jul 1.


Role of GABRA2 in moderating subjective responses to alcohol.

Roh S, Matsushita S, Hara S, Maesato H, Matsui T, Suzuki G, Miyakawa T, Ramchandani VA, Li TK, Higuchi S.

Alcohol Clin Exp Res. 2011 Mar;35(3):400-7. doi: 10.1111/j.1530-0277.2010.01357.x. Epub 2010 Nov 30.


GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride.

Pierucci-Lagha A, Covault J, Feinn R, Nellissery M, Hernandez-Avila C, Oncken C, Morrow AL, Kranzler HR.

Neuropsychopharmacology. 2005 Jun;30(6):1193-203.


The effect of naltrexone on alcohol's stimulant properties and self-administration behavior in social drinkers: influence of gender and genotype.

Setiawan E, Pihl RO, Cox SM, Gianoulakis C, Palmour RM, Benkelfat C, Leyton M.

Alcohol Clin Exp Res. 2011 Jun;35(6):1134-41. doi: 10.1111/j.1530-0277.2011.01446.x. Epub 2011 Mar 15.


Effect of GABRA2 genotype on development of incentive-motivation circuitry in a sample enriched for alcoholism risk.

Heitzeg MM, Villafuerte S, Weiland BJ, Enoch MA, Burmeister M, Zubieta JK, Zucker RA.

Neuropsychopharmacology. 2014 Dec;39(13):3077-86. doi: 10.1038/npp.2014.161. Epub 2014 Jun 30.


The GABA(B) receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats.

Liang JH, Chen F, Krstew E, Cowen MS, Carroll FY, Crawford D, Beart PM, Lawrence AJ.

Neuropharmacology. 2006 Apr;50(5):632-9. Epub 2006 Jan 9. Erratum in: Neuropharmacology. 2006 Sep;51(3):692.


Associations among GABRG1, level of response to alcohol, and drinking behaviors.

Ray LA, Hutchison KE.

Alcohol Clin Exp Res. 2009 Aug;33(8):1382-90. doi: 10.1111/j.1530-0277.2009.00968.x. Epub 2009 May 4.


Alcohol-Induced Stimulation Mediates the Effect of a GABRA2 SNP on Alcohol Self-Administrated among Alcohol-Dependent Individuals.

Boyd SJ, Schacht JP, Prisciandaro JJ, Voronin K, Anton RF.

Alcohol Alcohol. 2016 Sep;51(5):549-54. doi: 10.1093/alcalc/agw024. Epub 2016 Apr 26.


Intravenous ethanol infusions can mimic the time course of breath alcohol concentrations following oral alcohol administration in healthy volunteers.

Ramchandani VA, Plawecki M, Li TK, O'Connor S.

Alcohol Clin Exp Res. 2009 May;33(5):938-44. doi: 10.1111/j.1530-0277.2009.00906.x. Epub 2009 Mar 11.


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