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Items: 1 to 20 of 371

1.

TXNIP in Agrp neurons regulates adiposity, energy expenditure, and central leptin sensitivity.

Blouet C, Liu SM, Jo YH, Chua S, Schwartz GJ.

J Neurosci. 2012 Jul 18;32(29):9870-7. doi: 10.1523/JNEUROSCI.0353-12.2012.

2.

Nutrient-sensing hypothalamic TXNIP links nutrient excess to energy imbalance in mice.

Blouet C, Schwartz GJ.

J Neurosci. 2011 Apr 20;31(16):6019-27. doi: 10.1523/JNEUROSCI.6498-10.2011.

3.

ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in male mice.

Huang H, Lee SH, Ye C, Lima IS, Oh BC, Lowell BB, Zabolotny JM, Kim YB.

Endocrinology. 2013 Oct;154(10):3660-70. doi: 10.1210/en.2013-1343. Epub 2013 Jul 24.

4.

Coordinated regulation of hepatic energy stores by leptin and hypothalamic agouti-related protein.

Warne JP, Varonin JM, Nielsen SS, Olofsson LE, Kaelin CB, Chua S Jr, Barsh GS, Koliwad SK, Xu AW.

J Neurosci. 2013 Jul 17;33(29):11972-85. doi: 10.1523/JNEUROSCI.0830-13.2013. Retraction in: J Neurosci. 2014 Oct 8;34(41):13865.

5.

AgRP Neuron-Specific Deletion of Glucocorticoid Receptor Leads to Increased Energy Expenditure and Decreased Body Weight in Female Mice on a High-Fat Diet.

Shibata M, Banno R, Sugiyama M, Tominaga T, Onoue T, Tsunekawa T, Azuma Y, Hagiwara D, Lu W, Ito Y, Goto M, Suga H, Sugimura Y, Oiso Y, Arima H.

Endocrinology. 2016 Apr;157(4):1457-66. doi: 10.1210/en.2015-1430. Epub 2016 Feb 18.

PMID:
26889940
6.

AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons.

Claret M, Smith MA, Batterham RL, Selman C, Choudhury AI, Fryer LG, Clements M, Al-Qassab H, Heffron H, Xu AW, Speakman JR, Barsh GS, Viollet B, Vaulont S, Ashford ML, Carling D, Withers DJ.

J Clin Invest. 2007 Aug;117(8):2325-36.

7.

Deletion of ATF4 in AgRP Neurons Promotes Fat Loss Mainly via Increasing Energy Expenditure.

Deng J, Yuan F, Guo Y, Xiao Y, Niu Y, Deng Y, Han X, Guan Y, Chen S, Guo F.

Diabetes. 2017 Mar;66(3):640-650. doi: 10.2337/db16-0954. Epub 2016 Dec 19. Erratum in: Diabetes. 2017 Dec;66(12 ):3142.

8.

Gpr17 in AgRP Neurons Regulates Feeding and Sensitivity to Insulin and Leptin.

Ren H, Cook JR, Kon N, Accili D.

Diabetes. 2015 Nov;64(11):3670-9. doi: 10.2337/db15-0390. Epub 2015 Jul 15.

9.

Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis.

Wu CS, Bongmba OYN, Yue J, Lee JH, Lin L, Saito K, Pradhan G, Li DP, Pan HL, Xu A, Guo S, Xu Y, Sun Y.

Int J Mol Sci. 2017 Apr 14;18(4). pii: E832. doi: 10.3390/ijms18040832.

10.

Hypothalamic SIRT1 prevents age-associated weight gain by improving leptin sensitivity in mice.

Sasaki T, Kikuchi O, Shimpuku M, Susanti VY, Yokota-Hashimoto H, Taguchi R, Shibusawa N, Sato T, Tang L, Amano K, Kitazumi T, Kuroko M, Fujita Y, Maruyama J, Lee YS, Kobayashi M, Nakagawa T, Minokoshi Y, Harada A, Yamada M, Kitamura T.

Diabetologia. 2014 Apr;57(4):819-31. doi: 10.1007/s00125-013-3140-5. Epub 2013 Dec 29.

11.

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.

Gong L, Yao F, Hockman K, Heng HH, Morton GJ, Takeda K, Akira S, Low MJ, Rubinstein M, MacKenzie RG.

Endocrinology. 2008 Jul;149(7):3346-54. doi: 10.1210/en.2007-0945. Epub 2008 Apr 10.

12.

A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding.

Dodd GT, Andrews ZB, Simonds SE, Michael NJ, DeVeer M, Brüning JC, Spanswick D, Cowley MA, Tiganis T.

Cell Metab. 2017 Aug 1;26(2):375-393.e7. doi: 10.1016/j.cmet.2017.07.013. Erratum in: Cell Metab. 2017 Sep 5;26(3):577.

PMID:
28768176
13.

Dominant role of the p110beta isoform of PI3K over p110alpha in energy homeostasis regulation by POMC and AgRP neurons.

Al-Qassab H, Smith MA, Irvine EE, Guillermet-Guibert J, Claret M, Choudhury AI, Selman C, Piipari K, Clements M, Lingard S, Chandarana K, Bell JD, Barsh GS, Smith AJ, Batterham RL, Ashford ML, Vanhaesebroeck B, Withers DJ.

Cell Metab. 2009 Nov;10(5):343-54. doi: 10.1016/j.cmet.2009.09.008.

14.

Neuropeptide Y and agouti-related peptide mediate complementary functions of hyperphagia and reduced energy expenditure in leptin receptor deficiency.

Luo N, Marcelin G, Liu SM, Schwartz G, Chua S Jr.

Endocrinology. 2011 Mar;152(3):883-9. doi: 10.1210/en.2010-1135. Epub 2011 Feb 1.

15.

Leptin Signaling in AgRP Neurons Modulates Puberty Onset and Adult Fertility in Mice.

Egan OK, Inglis MA, Anderson GM.

J Neurosci. 2017 Apr 5;37(14):3875-3886. doi: 10.1523/JNEUROSCI.3138-16.2017. Epub 2017 Mar 8.

16.

FoxO1 target Gpr17 activates AgRP neurons to regulate food intake.

Ren H, Orozco IJ, Su Y, Suyama S, Gutiérrez-Juárez R, Horvath TL, Wardlaw SL, Plum L, Arancio O, Accili D.

Cell. 2012 Jun 8;149(6):1314-26. doi: 10.1016/j.cell.2012.04.032. Erratum in: Cell. 2013 May 23;153(5):1166.

17.

Activation of Stat3 signaling in AgRP neurons promotes locomotor activity.

Mesaros A, Koralov SB, Rother E, Wunderlich FT, Ernst MB, Barsh GS, Rajewsky K, Brüning JC.

Cell Metab. 2008 Mar;7(3):236-48. doi: 10.1016/j.cmet.2008.01.007.

18.

Effects of AgRP inhibition on energy balance and metabolism in rodent models.

Dutia R, Kim AJ, Modes M, Rothlein R, Shen JM, Tian YE, Ihbais J, Victory SF, Valcarce C, Wardlaw SL.

PLoS One. 2013 Jun 6;8(6):e65317. doi: 10.1371/journal.pone.0065317. Print 2013.

19.

Induction of the metabolic regulator Txnip in fasting-induced and natural torpor.

Hand LE, Saer BR, Hui ST, Jinnah HA, Steinlechner S, Loudon AS, Bechtold DA.

Endocrinology. 2013 Jun;154(6):2081-91. doi: 10.1210/en.2012-2051. Epub 2013 Apr 12.

20.

Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus.

Baver SB, Hope K, Guyot S, Bjørbaek C, Kaczorowski C, O'Connell KM.

J Neurosci. 2014 Apr 16;34(16):5486-96. doi: 10.1523/JNEUROSCI.4861-12.2014.

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