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Items: 1 to 20 of 106

1.

The dimeric platelet collagen receptor GPVI-Fc reduces platelet adhesion to activated endothelium and preserves myocardial function after transient ischemia in mice.

Schönberger T, Ziegler M, Borst O, Konrad I, Nieswandt B, Massberg S, Ochmann C, Jürgens T, Seizer P, Langer H, Münch G, Ungerer M, Preissner KT, Elvers M, Gawaz M.

Am J Physiol Cell Physiol. 2012 Oct 1;303(7):C757-66. doi: 10.1152/ajpcell.00060.2012. Epub 2012 Jul 18.

2.

Impact of glycoprotein VI and platelet adhesion on atherosclerosis--a possible role of fibronectin.

Bültmann A, Li Z, Wagner S, Peluso M, Schönberger T, Weis C, Konrad I, Stellos K, Massberg S, Nieswandt B, Gawaz M, Ungerer M, Münch G.

J Mol Cell Cardiol. 2010 Sep;49(3):532-42. doi: 10.1016/j.yjmcc.2010.04.009. Epub 2010 Apr 27.

PMID:
20430036
3.

Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo.

Massberg S, Konrad I, Bültmann A, Schulz C, Münch G, Peluso M, Lorenz M, Schneider S, Besta F, Müller I, Hu B, Langer H, Kremmer E, Rudelius M, Heinzmann U, Ungerer M, Gawaz M.

FASEB J. 2004 Feb;18(2):397-9. Epub 2003 Dec 4.

PMID:
14656994
4.

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.

Jandrot-Perrus M, Busfield S, Lagrue AH, Xiong X, Debili N, Chickering T, Le Couedic JP, Goodearl A, Dussault B, Fraser C, Vainchenker W, Villeval JL.

Blood. 2000 Sep 1;96(5):1798-807.

5.

The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice.

Ziegler M, Elvers M, Baumer Y, Leder C, Ochmann C, Schönberger T, Jürgens T, Geisler T, Schlosshauer B, Lunov O, Engelhardt S, Simmet T, Gawaz M.

Circulation. 2012 Feb 7;125(5):685-96. doi: 10.1161/CIRCULATIONAHA.111.070508. Epub 2012 Jan 5.

6.

Relative antithrombotic effect of soluble GPVI dimer compared with anti-GPVI antibodies in mice.

Grüner S, Prostredna M, Koch M, Miura Y, Schulte V, Jung SM, Moroi M, Nieswandt B.

Blood. 2005 Feb 15;105(4):1492-9. Epub 2004 Oct 26.

7.

Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo.

Schulz C, Penz S, Hoffmann C, Langer H, Gillitzer A, Schneider S, Brandl R, Seidl S, Massberg S, Pichler B, Kremmer E, Stellos K, Schönberger T, Siess W, Gawaz M.

Basic Res Cardiol. 2008 Jul;103(4):356-67. doi: 10.1007/s00395-008-0722-3. Epub 2008 Apr 22.

PMID:
18431526
8.

EMMPRIN (CD147) is a novel receptor for platelet GPVI and mediates platelet rolling via GPVI-EMMPRIN interaction.

Seizer P, Borst O, Langer HF, Bültmann A, Münch G, Herouy Y, Stellos K, Krämer B, Bigalke B, Büchele B, Bachem MG, Vestweber D, Simmet T, Gawaz M, May AE.

Thromb Haemost. 2009 Apr;101(4):682-6.

PMID:
19350111
9.

Inhibition of Platelet GPVI Protects Against Myocardial Ischemia-Reperfusion Injury.

Pachel C, Mathes D, Arias-Loza AP, Heitzmann W, Nordbeck P, Deppermann C, Lorenz V, Hofmann U, Nieswandt B, Frantz S.

Arterioscler Thromb Vasc Biol. 2016 Apr;36(4):629-35. doi: 10.1161/ATVBAHA.115.305873. Epub 2016 Feb 25.

11.

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo.

Massberg S, Gawaz M, Grüner S, Schulte V, Konrad I, Zohlnhöfer D, Heinzmann U, Nieswandt B.

J Exp Med. 2003 Jan 6;197(1):41-9.

12.

Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding.

Kleinschnitz C, Pozgajova M, Pham M, Bendszus M, Nieswandt B, Stoll G.

Circulation. 2007 May 1;115(17):2323-30. Epub 2007 Apr 16.

13.

A novel antiplatelet antibody therapy that induces cAMP-dependent endocytosis of the GPVI/Fc receptor gamma-chain complex.

Takayama H, Hosaka Y, Nakayama K, Shirakawa K, Naitoh K, Matsusue T, Shinozaki M, Honda M, Yatagai Y, Kawahara T, Hirose J, Yokoyama T, Kurihara M, Furusako S.

J Clin Invest. 2008 May;118(5):1785-95. doi: 10.1172/JCI32513.

14.

Vitronectin receptor (alpha(v)beta3) mediates platelet adhesion to the luminal aspect of endothelial cells: implications for reperfusion in acute myocardial infarction.

Gawaz M, Neumann FJ, Dickfeld T, Reininger A, Adelsberger H, Gebhardt A, Schömig A.

Circulation. 1997 Sep 16;96(6):1809-18.

15.

Platelet-collagen interaction: is GPVI the central receptor?

Nieswandt B, Watson SP.

Blood. 2003 Jul 15;102(2):449-61. Epub 2003 Mar 20. Review.

16.

The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in a receptor density-dependent fashion.

Chen H, Locke D, Liu Y, Liu C, Kahn ML.

J Biol Chem. 2002 Jan 25;277(4):3011-9. Epub 2001 Nov 26.

17.

Human platelet glycoprotein VI function is antagonized by monoclonal antibody-derived Fab fragments.

Lecut C, Feeney LA, Kingsbury G, Hopkins J, Lanza F, Gachet C, Villeval JL, Jandrot-Perrus M.

J Thromb Haemost. 2003 Dec;1(12):2653-62.

18.

The immunoadhesin glycoprotein VI-Fc regulates arterial remodelling after mechanical injury in ApoE-/- mice.

Schönberger T, Siegel-Axel D, Bussl R, Richter S, Judenhofer MS, Haubner R, Reischl G, Klingel K, Münch G, Seizer P, Pichler BJ, Gawaz M.

Cardiovasc Res. 2008 Oct 1;80(1):131-7. doi: 10.1093/cvr/cvn169. Epub 2008 Jun 19.

PMID:
18566102
19.

Junctional adhesion molecule A expressed on human CD34+ cells promotes adhesion on vascular wall and differentiation into endothelial progenitor cells.

Stellos K, Langer H, Gnerlich S, Panagiota V, Paul A, Schönberger T, Ninci E, Menzel D, Mueller I, Bigalke B, Geisler T, Bültmann A, Lindemann S, Gawaz M.

Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1127-36. doi: 10.1161/ATVBAHA.110.204370. Epub 2010 Apr 8.

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