Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 110

1.

Roles of heterotypic CCN2/CTGF-CCN3/NOV and homotypic CCN2-CCN2 interactions in expression of the differentiated phenotype of chondrocytes.

Hoshijima M, Hattori T, Aoyama E, Nishida T, Yamashiro T, Takigawa M.

FEBS J. 2012 Oct;279(19):3584-3597. doi: 10.1111/j.1742-4658.2012.08717.x. Epub 2012 Aug 28.

2.

N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan.

Aoyama E, Hattori T, Hoshijima M, Araki D, Nishida T, Kubota S, Takigawa M.

Biochem J. 2009 May 27;420(3):413-20. doi: 10.1042/BJ20081991.

PMID:
19298220
3.

Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage.

Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M.

J Bone Miner Res. 2008 Nov;23(11):1751-64. doi: 10.1359/jbmr.080615.

4.

CCN3 (NOV) is a negative regulator of CCN2 (CTGF) and a novel endogenous inhibitor of the fibrotic pathway in an in vitro model of renal disease.

Riser BL, Najmabadi F, Perbal B, Peterson DR, Rambow JA, Riser ML, Sukowski E, Yeger H, Riser SC.

Am J Pathol. 2009 May;174(5):1725-34. doi: 10.2353/ajpath.2009.080241. Epub 2009 Apr 9.

5.

Protein Imaging of CCN2 and CCN3 in Living Cells.

Hattori T, Hoshijima M, Takigawa M.

Methods Mol Biol. 2017;1489:211-215.

PMID:
27734379
6.

The Wnt antagonist Wif-1 interacts with CTGF and inhibits CTGF activity.

Surmann-Schmitt C, Sasaki T, Hattori T, Eitzinger N, Schett G, von der Mark K, Stock M.

J Cell Physiol. 2012 May;227(5):2207-16. doi: 10.1002/jcp.22957.

PMID:
21928342
7.

Novel chondrogenic and chondroprotective effects of the natural compound harmine.

Hara ES, Ono M, Kubota S, Sonoyama W, Oida Y, Hattori T, Nishida T, Furumatsu T, Ozaki T, Takigawa M, Kuboki T.

Biochimie. 2013 Feb;95(2):374-81. doi: 10.1016/j.biochi.2012.10.016. Epub 2012 Oct 29.

PMID:
23116713
8.

Transforming growth factor β controls CCN3 expression in nucleus pulposus cells of the intervertebral disc.

Tran CM, Smith HE, Symes A, Rittié L, Perbal B, Shapiro IM, Risbud MV.

Arthritis Rheum. 2011 Oct;63(10):3022-31. doi: 10.1002/art.30468.

9.

The regenerative effects of CCN2 independent modules on chondrocytes in vitro and osteoarthritis models in vivo.

Abd El Kader T, Kubota S, Nishida T, Hattori T, Aoyama E, Janune D, Hara ES, Ono M, Tabata Y, Kuboki T, Takigawa M.

Bone. 2014 Feb;59:180-8. doi: 10.1016/j.bone.2013.11.010. Epub 2013 Nov 20.

PMID:
24269276
10.

New target genes for NOV/CCN3 in chondrocytes: TGF-beta2 and type X collagen.

Lafont J, Jacques C, Le Dreau G, Calhabeu F, Thibout H, Dubois C, Berenbaum F, Laurent M, Martinerie C.

J Bone Miner Res. 2005 Dec;20(12):2213-23. Epub 2005 Aug 22. Erratum in: J Bone Miner Res. 2006 Feb;21(2):352.

11.

Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor).

Nishida T, Kubota S, Kojima S, Kuboki T, Nakao K, Kushibiki T, Tabata Y, Takigawa M.

J Bone Miner Res. 2004 Aug;19(8):1308-19. Epub 2004 Mar 29.

13.

CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes.

Maeda A, Nishida T, Aoyama E, Kubota S, Lyons KM, Kuboki T, Takigawa M.

J Biochem. 2009 Feb;145(2):207-16. doi: 10.1093/jb/mvn159. Epub 2008 Nov 27.

14.

CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes.

Fujisawa T, Hattori T, Ono M, Uehara J, Kubota S, Kuboki T, Takigawa M.

Osteoarthritis Cartilage. 2008 Jul;16(7):787-95. doi: 10.1016/j.joca.2007.11.001. Epub 2008 Mar 4.

15.

Urinary mRNA expression of CCN2/CCN3 as a noninvasive marker for monitoring glomerular structure changes in nondiabetic chronic kidney disease.

Chen L, Wu YG, Liu D, Lv LL, Zheng M, Ni HF, Cao YH, Liu H, Zhang P, Zhang JD, Liu BC.

Biomarkers. 2012 Dec;17(8):714-20. doi: 10.3109/1354750X.2012.722229. Epub 2012 Oct 15.

PMID:
23061738
16.

Vinculin functions as regulator of chondrogenesis.

Koshimizu T, Kawai M, Kondou H, Tachikawa K, Sakai N, Ozono K, Michigami T.

J Biol Chem. 2012 May 4;287(19):15760-75. doi: 10.1074/jbc.M111.308072. Epub 2012 Mar 13.

17.

Low-intensity pulsed ultrasound (LIPUS) treatment of cultured chondrocytes stimulates production of CCN family protein 2 (CCN2), a protein involved in the regeneration of articular cartilage: mechanism underlying this stimulation.

Nishida T, Kubota S, Aoyama E, Yamanaka N, Lyons KM, Takigawa M.

Osteoarthritis Cartilage. 2017 May;25(5):759-769. doi: 10.1016/j.joca.2016.10.003. Epub 2016 Oct 8.

PMID:
27729291
18.

CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1alpha expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition.

Nishida T, Kondo S, Maeda A, Kubota S, Lyons KM, Takigawa M.

Bone. 2009 Jan;44(1):24-31. doi: 10.1016/j.bone.2008.08.125. Epub 2008 Sep 13.

19.

Myeloid Zinc Finger 1 (MZF-1) Regulates Expression of the CCN2/CTGF and CCN3/NOV Genes in the Hematopoietic Compartment.

Piszczatowski RT, Rafferty BJ, Rozado A, Parziale JV, Lents NH.

J Cell Physiol. 2015 Nov;230(11):2634-9. doi: 10.1002/jcp.25021.

PMID:
25899830
20.

Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth.

Tomita N, Hattori T, Itoh S, Aoyama E, Yao M, Yamashiro T, Takigawa M.

PLoS One. 2013;8(3):e59226. doi: 10.1371/journal.pone.0059226. Epub 2013 Mar 28.

Supplemental Content

Support Center