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Items: 1 to 20 of 118

1.

Laminin induced local axonal translation of β-actin mRNA is impaired in SMN-deficient motoneurons.

Rathod R, Havlicek S, Frank N, Blum R, Sendtner M.

Histochem Cell Biol. 2012 Nov;138(5):737-48. doi: 10.1007/s00418-012-0989-1. Epub 2012 Jul 19.

PMID:
22810847
2.

Smn, the spinal muscular atrophy-determining gene product, modulates axon growth and localization of beta-actin mRNA in growth cones of motoneurons.

Rossoll W, Jablonka S, Andreassi C, Kröning AK, Karle K, Monani UR, Sendtner M.

J Cell Biol. 2003 Nov 24;163(4):801-12. Epub 2003 Nov 17.

3.

The heterogeneous nuclear ribonucleoprotein-R is necessary for axonal beta-actin mRNA translocation in spinal motor neurons.

Glinka M, Herrmann T, Funk N, Havlicek S, Rossoll W, Winkler C, Sendtner M.

Hum Mol Genet. 2010 May 15;19(10):1951-66. doi: 10.1093/hmg/ddq073. Epub 2010 Feb 18.

PMID:
20167579
4.

PTEN depletion rescues axonal growth defect and improves survival in SMN-deficient motor neurons.

Ning K, Drepper C, Valori CF, Ahsan M, Wyles M, Higginbottom A, Herrmann T, Shaw P, Azzouz M, Sendtner M.

Hum Mol Genet. 2010 Aug 15;19(16):3159-68. doi: 10.1093/hmg/ddq226. Epub 2010 Jun 4.

PMID:
20525971
5.

Pathogenesis of proximal autosomal recessive spinal muscular atrophy.

Simic G.

Acta Neuropathol. 2008 Sep;116(3):223-34. doi: 10.1007/s00401-008-0411-1. Epub 2008 Jul 16. Review.

PMID:
18629520
6.

Deficiency of the Survival of Motor Neuron Protein Impairs mRNA Localization and Local Translation in the Growth Cone of Motor Neurons.

Fallini C, Donlin-Asp PG, Rouanet JP, Bassell GJ, Rossoll W.

J Neurosci. 2016 Mar 30;36(13):3811-20. doi: 10.1523/JNEUROSCI.2396-15.2016.

7.

Interaction of survival of motor neuron (SMN) and HuD proteins with mRNA cpg15 rescues motor neuron axonal deficits.

Akten B, Kye MJ, Hao le T, Wertz MH, Singh S, Nie D, Huang J, Merianda TT, Twiss JL, Beattie CE, Steen JA, Sahin M.

Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10337-42. doi: 10.1073/pnas.1104928108. Epub 2011 Jun 7.

8.

The spinal muscular atrophy disease protein SMN is linked to the Rho-kinase pathway via profilin.

Nölle A, Zeug A, van Bergeijk J, Tönges L, Gerhard R, Brinkmann H, Al Rayes S, Hensel N, Schill Y, Apkhazava D, Jablonka S, O'mer J, Srivastav RK, Baasner A, Lingor P, Wirth B, Ponimaskin E, Niedenthal R, Grothe C, Claus P.

Hum Mol Genet. 2011 Dec 15;20(24):4865-78. doi: 10.1093/hmg/ddr425. Epub 2011 Sep 14.

PMID:
21920940
9.

Death of motoneurons induced by trophic deprivation or by excitotoxicity is not prevented by overexpression of SMN.

Cisterni C, Kallenbach S, Jordier F, Bagnis C, Pettmann B.

Neurobiol Dis. 2001 Apr;8(2):240-51.

PMID:
11300720
10.

Dynamics of survival of motor neuron (SMN) protein interaction with the mRNA-binding protein IMP1 facilitates its trafficking into motor neuron axons.

Fallini C, Rouanet JP, Donlin-Asp PG, Guo P, Zhang H, Singer RH, Rossoll W, Bassell GJ.

Dev Neurobiol. 2014 Mar;74(3):319-332. doi: 10.1002/dneu.22111. Epub 2013 Oct 4.

11.

Defective Ca2+ channel clustering in axon terminals disturbs excitability in motoneurons in spinal muscular atrophy.

Jablonka S, Beck M, Lechner BD, Mayer C, Sendtner M.

J Cell Biol. 2007 Oct 8;179(1):139-49.

12.

Brief report: phenotypic rescue of induced pluripotent stem cell-derived motoneurons of a spinal muscular atrophy patient.

Chang T, Zheng W, Tsark W, Bates S, Huang H, Lin RJ, Yee JK.

Stem Cells. 2011 Dec;29(12):2090-3. doi: 10.1002/stem.749.

13.

SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA.

Caraballo-Miralles V, Cardona-Rossinyol A, Garcera A, Villalonga P, Soler RM, Olmos G, Lladó J.

Mol Cell Neurosci. 2012 Mar;49(3):282-9. doi: 10.1016/j.mcn.2011.12.003. Epub 2011 Dec 16.

PMID:
22197680
14.

Distinct and overlapping alterations in motor and sensory neurons in a mouse model of spinal muscular atrophy.

Jablonka S, Karle K, Sandner B, Andreassi C, von Au K, Sendtner M.

Hum Mol Genet. 2006 Feb 1;15(3):511-8. Epub 2006 Jan 5.

PMID:
16396995
15.

Valproic acid blocks excitability in SMA type I mouse motor neurons.

Rak K, Lechner BD, Schneider C, Drexl H, Sendtner M, Jablonka S.

Neurobiol Dis. 2009 Dec;36(3):477-87. doi: 10.1016/j.nbd.2009.08.014. Epub 2009 Sep 4.

PMID:
19733665
16.

Celecoxib increases SMN and survival in a severe spinal muscular atrophy mouse model via p38 pathway activation.

Farooq F, Abadía-Molina F, MacKenzie D, Hadwen J, Shamim F, O'Reilly S, Holcik M, MacKenzie A.

Hum Mol Genet. 2013 Sep 1;22(17):3415-24. doi: 10.1093/hmg/ddt191. Epub 2013 May 7.

PMID:
23656793
17.

A new model to study spinal muscular atrophy: neurite degeneration and cell death is counteracted by BCL-X(L) Overexpression in motoneurons.

Garcera A, Mincheva S, Gou-Fabregas M, Caraballo-Miralles V, Lladó J, Comella JX, Soler RM.

Neurobiol Dis. 2011 Jun;42(3):415-26. doi: 10.1016/j.nbd.2011.02.003. Epub 2011 Feb 16.

PMID:
21333739
18.

Presynaptic localization of Smn and hnRNP R in axon terminals of embryonic and postnatal mouse motoneurons.

Dombert B, Sivadasan R, Simon CM, Jablonka S, Sendtner M.

PLoS One. 2014 Oct 22;9(10):e110846. doi: 10.1371/journal.pone.0110846. eCollection 2014.

19.

A role for complexes of survival of motor neurons (SMN) protein with gemins and profilin in neurite-like cytoplasmic extensions of cultured nerve cells.

Sharma A, Lambrechts A, Hao le T, Le TT, Sewry CA, Ampe C, Burghes AH, Morris GE.

Exp Cell Res. 2005 Sep 10;309(1):185-97.

PMID:
15975577
20.

ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN.

Groen EJ, Fumoto K, Blokhuis AM, Engelen-Lee J, Zhou Y, van den Heuvel DM, Koppers M, van Diggelen F, van Heest J, Demmers JA, Kirby J, Shaw PJ, Aronica E, Spliet WG, Veldink JH, van den Berg LH, Pasterkamp RJ.

Hum Mol Genet. 2013 Sep 15;22(18):3690-704. doi: 10.1093/hmg/ddt222. Epub 2013 May 15.

PMID:
23681068

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