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Items: 1 to 20 of 107

1.

Lysophosphatidic acid (LPA) and its receptors: role in airway inflammation and remodeling.

Zhao Y, Natarajan V.

Biochim Biophys Acta. 2013 Jan;1831(1):86-92. doi: 10.1016/j.bbalip.2012.06.014. Epub 2012 Jul 15. Review.

2.

Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma.

Zhao Y, Tong J, He D, Pendyala S, Evgeny B, Chun J, Sperling AI, Natarajan V.

Respir Res. 2009 Nov 20;10:114. doi: 10.1186/1465-9921-10-114.

3.

Lysophosphatidic acid signaling in airway epithelium: role in airway inflammation and remodeling.

Zhao Y, Natarajan V.

Cell Signal. 2009 Mar;21(3):367-77. doi: 10.1016/j.cellsig.2008.10.010. Epub 2008 Oct 26. Review.

4.

Polyunsaturated lysophosphatidic acid as a potential asthma biomarker.

Ackerman SJ, Park GY, Christman JW, Nyenhuis S, Berdyshev E, Natarajan V.

Biomark Med. 2016;10(2):123-35. doi: 10.2217/bmm.15.93. Epub 2016 Jan 14. Review.

5.

Lysophosphatidic acid enhances pulmonary epithelial barrier integrity and protects endotoxin-induced epithelial barrier disruption and lung injury.

He D, Su Y, Usatyuk PV, Spannhake EW, Kogut P, Solway J, Natarajan V, Zhao Y.

J Biol Chem. 2009 Sep 4;284(36):24123-32. doi: 10.1074/jbc.M109.007393. Epub 2009 Jul 8.

6.

Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.

Zhao J, He D, Su Y, Berdyshev E, Chun J, Natarajan V, Zhao Y.

Am J Physiol Lung Cell Mol Physiol. 2011 Oct;301(4):L547-56. doi: 10.1152/ajplung.00058.2011. Epub 2011 Aug 5.

7.

Lysophosphatidic acid increases soluble ST2 expression in mouse lung and human bronchial epithelial cells.

Zhao J, Chen Q, Li H, Myerburg M, Spannhake EW, Natarajan V, Zhao Y.

Cell Signal. 2012 Jan;24(1):77-85. doi: 10.1016/j.cellsig.2011.08.004. Epub 2011 Aug 17.

8.

The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis after lung injury.

Funke M, Zhao Z, Xu Y, Chun J, Tager AM.

Am J Respir Cell Mol Biol. 2012 Mar;46(3):355-64. doi: 10.1165/rcmb.2010-0155OC. Epub 2011 Oct 20.

9.

Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways.

Zhao J, He D, Berdyshev E, Zhong M, Salgia R, Morris AJ, Smyth SS, Natarajan V, Zhao Y.

Biochem J. 2011 Oct 1;439(1):45-55. doi: 10.1042/BJ20110274.

10.

Regulation of silicosis formation by lysophosphatidic acid and its receptors.

Cong C, Mao L, Zhang Y, Zhao Z, Xu X, Zhao J.

Exp Lung Res. 2014 Sep;40(7):317-26. doi: 10.3109/01902148.2014.920438. Epub 2014 Jun 13.

PMID:
24926730
11.

Lysophosphatidic acid is detectable in human bronchoalveolar lavage fluids at baseline and increased after segmental allergen challenge.

Georas SN, Berdyshev E, Hubbard W, Gorshkova IA, Usatyuk PV, Saatian B, Myers AC, Williams MA, Xiao HQ, Liu M, Natarajan V.

Clin Exp Allergy. 2007 Mar;37(3):311-22.

PMID:
17359381
12.

Comparing the differential effects of LPA on the barrier function of human pulmonary endothelial cells.

Ren Y, Guo L, Tang X, Apparsundaram S, Kitson C, Deguzman J, Fuentes ME, Coyle L, Majmudar R, Allard J, Truitt T, Hamid R, Chen Y, Qian Y, Budd DC.

Microvasc Res. 2013 Jan;85:59-67. doi: 10.1016/j.mvr.2012.10.004. Epub 2012 Oct 16.

PMID:
23084965
13.

TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.

Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG.

J Lipid Res. 2011 Jul;52(7):1307-18. doi: 10.1194/jlr.M008045. Epub 2011 Apr 26.

14.

Current progress in non-Edg family LPA receptor research.

Yanagida K, Kurikawa Y, Shimizu T, Ishii S.

Biochim Biophys Acta. 2013 Jan;1831(1):33-41. doi: 10.1016/j.bbalip.2012.08.003. Epub 2012 Aug 11. Review.

PMID:
22902318
15.

Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.

Shea BS, Tager AM.

Proc Am Thorac Soc. 2012 Jul;9(3):102-10. doi: 10.1513/pats.201201-005AW. Review.

PMID:
22802282
16.

Comparative analyses of lysophosphatidic acid receptor-mediated signaling.

Fukushima N, Ishii S, Tsujiuchi T, Kagawa N, Katoh K.

Cell Mol Life Sci. 2015 Jun;72(12):2377-94. doi: 10.1007/s00018-015-1872-8. Epub 2015 Mar 4. Review.

PMID:
25732591
17.

Lysophosphatidic acid: a potential mediator of osteoblast-osteoclast signaling in bone.

Sims SM, Panupinthu N, Lapierre DM, Pereverzev A, Dixon SJ.

Biochim Biophys Acta. 2013 Jan;1831(1):109-16. doi: 10.1016/j.bbalip.2012.08.001. Epub 2012 Aug 7. Review.

PMID:
22892679
18.

Biological roles of lysophosphatidic acid signaling through its production by autotaxin.

Okudaira S, Yukiura H, Aoki J.

Biochimie. 2010 Jun;92(6):698-706. doi: 10.1016/j.biochi.2010.04.015. Epub 2010 Apr 22. Review.

PMID:
20417246
19.

Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

Xu MY, Porte J, Knox AJ, Weinreb PH, Maher TM, Violette SM, McAnulty RJ, Sheppard D, Jenkins G.

Am J Pathol. 2009 Apr;174(4):1264-79. doi: 10.2353/ajpath.2009.080160. Epub 2009 Jan 15.

20.

Lysophosphatidic acid receptors in cancer pathobiology.

Tsujiuchi T, Araki M, Hirane M, Dong Y, Fukushima N.

Histol Histopathol. 2014 Mar;29(3):313-21. doi: 10.14670/HH-29.313. Epub 2013 Nov 6. Review.

PMID:
24194373

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