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Items: 1 to 20 of 137

1.

Epigenetic regulation of DACT2, a key component of the Wnt signalling pathway in human lung cancer.

Jia Y, Yang Y, Brock MV, Zhan Q, Herman JG, Guo M.

J Pathol. 2013 Jun;230(2):194-204. doi: 10.1002/path.4073.

2.

Epigenetic regulation of the Wnt signaling inhibitor DACT2 in human hepatocellular carcinoma.

Zhang X, Yang Y, Liu X, Herman JG, Brock MV, Licchesi JD, Yue W, Pei X, Guo M.

Epigenetics. 2013 Apr;8(4):373-82. doi: 10.4161/epi.24113. Epub 2013 Feb 28.

3.

Methylation of DACT2 promotes papillary thyroid cancer metastasis by activating Wnt signaling.

Zhao Z, Herman JG, Brock MV, Sheng J, Zhang M, Liu B, Guo M.

PLoS One. 2014 Nov 6;9(11):e112336. doi: 10.1371/journal.pone.0112336. eCollection 2014.

4.

Methylation of DACT2 accelerates esophageal cancer development by activating Wnt signaling.

Zhang M, Linghu E, Zhan Q, He T, Cao B, Brock MV, Herman JG, Xiang R, Guo M.

Oncotarget. 2016 Apr 5;7(14):17957-69. doi: 10.18632/oncotarget.7647.

5.

DACT2 is a functional tumor suppressor through inhibiting Wnt/β-catenin pathway and associated with poor survival in colon cancer.

Wang S, Dong Y, Zhang Y, Wang X, Xu L, Yang S, Li X, Dong H, Xu L, Su L, Ng SS, Chang Z, Sung JJ, Zhang X, Yu J.

Oncogene. 2015 May 14;34(20):2575-85. doi: 10.1038/onc.2014.201. Epub 2014 Jul 14.

6.

DACT2 is frequently methylated in human gastric cancer and methylation of DACT2 activated Wnt signaling.

Yu Y, Yan W, Liu X, Jia Y, Cao B, Yu Y, Lv Y, Brock MV, Herman JG, Licchesi J, Yang Y, Guo M.

Am J Cancer Res. 2014 Nov 19;4(6):710-24. eCollection 2014.

7.

Aberrant methylation of DACT1 and DACT2 are associated with tumor progression and poor prognosis in esophageal squamous cell carcinoma.

Guo YL, Shan BE, Guo W, Dong ZM, Zhou Z, Shen SP, Guo X, Liang J, Kuang G.

J Biomed Sci. 2017 Jan 11;24(1):6. doi: 10.1186/s12929-016-0308-6.

8.

Expression and epigenetic regulation of DACT1 and DACT2 in oral squamous cell carcinoma.

Schussel JL, Kalinke LP, Sassi LM, de Oliveira BV, Pedruzzi PA, Olandoski M, Alvares LE, Garlet GP, Trevilatto PC.

Cancer Biomark. 2015;15(1):11-7. doi: 10.3233/CBM-140436.

PMID:
25524937
9.

Epigenetic silencing of Aristaless-like homeobox-4, a potential tumor suppressor gene associated with lung cancer.

Liu WB, Han F, Du XH, Jiang X, Li YH, Liu Y, Chen HQ, Ao L, Cui ZH, Cao J, Liu JY.

Int J Cancer. 2014 Mar 15;134(6):1311-22. doi: 10.1002/ijc.28472. Epub 2013 Nov 11.

10.

Epigenetic regulation of Wnt signaling pathway gene SRY-related HMG-box 17 in papillary thyroid carcinoma.

Li JY, Han C, Zheng LL, Guo MZ.

Chin Med J (Engl). 2012 Oct;125(19):3526-31.

PMID:
23044318
11.

Promoter methylation-mediated silencing of β-catenin enhances invasiveness of non-small cell lung cancer and predicts adverse prognosis.

Miao Y, Wang L, Zhang X, Xu X, Jiang G, Fan C, Liu Y, Lin X, Yu J, Zhang Y, Wang E.

PLoS One. 2014 Nov 14;9(11):e112258. doi: 10.1371/journal.pone.0112258. eCollection 2014.

12.

CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer.

Liu X, Zhang X, Zhan Q, Brock MV, Herman JG, Guo M.

Cancer Biol Ther. 2012 Oct;13(12):1152-7. doi: 10.4161/cbt.21344. Epub 2012 Aug 23.

13.

Reduced expression of DACT2 promotes hepatocellular carcinoma progression: involvement of methylation-mediated gene silencing.

Gao S, Yang Z, Zheng ZY, Yao J, Zhang F, Wu LM, Xie HY, Zhou L, Zheng SS.

World J Surg Oncol. 2013 Mar 7;11:57. doi: 10.1186/1477-7819-11-57.

14.

Dact2 represses PITX2 transcriptional activation and cell proliferation through Wnt/beta-catenin signaling during odontogenesis.

Li X, Florez S, Wang J, Cao H, Amendt BA.

PLoS One. 2013;8(1):e54868. doi: 10.1371/journal.pone.0054868. Epub 2013 Jan 22.

15.

Wnt signaling pathway in non-small cell lung cancer.

Stewart DJ.

J Natl Cancer Inst. 2014 Jan;106(1):djt356. doi: 10.1093/jnci/djt356. Epub 2013 Dec 5. Review.

PMID:
24309006
16.

Silencing GPX3 Expression Promotes Tumor Metastasis in Human Thyroid Cancer.

Zhao H, Li J, Li X, Han C, Zhang Y, Zheng L, Guo M.

Curr Protein Pept Sci. 2015;16(4):316-21.

PMID:
25929866
17.

Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.

Taniguchi H, Yamamoto H, Hirata T, Miyamoto N, Oki M, Nosho K, Adachi Y, Endo T, Imai K, Shinomura Y.

Oncogene. 2005 Nov 24;24(53):7946-52.

PMID:
16007117
18.

Wnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumours.

Veeck J, Bektas N, Hartmann A, Kristiansen G, Heindrichs U, Knüchel R, Dahl E.

Breast Cancer Res. 2008;10(5):R82. doi: 10.1186/bcr2151. Epub 2008 Sep 30.

19.

DACT1, an antagonist to Wnt/β-catenin signaling, suppresses tumor cell growth and is frequently silenced in breast cancer.

Yin X, Xiang T, Li L, Su X, Shu X, Luo X, Huang J, Yuan Y, Peng W, Oberst M, Kelly K, Ren G, Tao Q.

Breast Cancer Res. 2013 Mar 12;15(2):R23. doi: 10.1186/bcr3399.

20.

XAF1 is frequently methylated in human esophageal cancer.

Chen XY, He QY, Guo MZ.

World J Gastroenterol. 2012 Jun 14;18(22):2844-9. doi: 10.3748/wjg.v18.i22.2844.

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