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Items: 1 to 20 of 143

1.

High-throughput synthesis of carbohydrates and functionalization of polyanhydride nanoparticles.

Carrillo-Conde BR, Roychoudhury R, Chavez-Santoscoy AV, Narasimhan B, Pohl NL.

J Vis Exp. 2012 Jul 6;(65). pii: 3967. doi: 10.3791/3967.

2.

Functionalization of polyanhydride microparticles with di-mannose influences uptake by and intracellular fate within dendritic cells.

Phanse Y, Carrillo-Conde BR, Ramer-Tait AE, Roychoudhury R, Pohl NL, Narasimhan B, Wannemuehler MJ, Bellaire BH.

Acta Biomater. 2013 Nov;9(11):8902-9. doi: 10.1016/j.actbio.2013.06.024. Epub 2013 Jun 22.

PMID:
23796408
3.

Mannose-functionalized "pathogen-like" polyanhydride nanoparticles target C-type lectin receptors on dendritic cells.

Carrillo-Conde B, Song EH, Chavez-Santoscoy A, Phanse Y, Ramer-Tait AE, Pohl NL, Wannemuehler MJ, Bellaire BH, Narasimhan B.

Mol Pharm. 2011 Oct 3;8(5):1877-86. doi: 10.1021/mp200213r. Epub 2011 Sep 13.

PMID:
21882825
4.

Combinatorial Synthesis of and high-throughput protein release from polymer film and nanoparticle libraries.

Petersen LK, Chavez-Santoscoy AV, Narasimhan B.

J Vis Exp. 2012 Sep 6;(67). pii: 3882. doi: 10.3791/3882.

5.

Tailoring the immune response by targeting C-type lectin receptors on alveolar macrophages using "pathogen-like" amphiphilic polyanhydride nanoparticles.

Chavez-Santoscoy AV, Roychoudhury R, Pohl NL, Wannemuehler MJ, Narasimhan B, Ramer-Tait AE.

Biomaterials. 2012 Jun;33(18):4762-72. doi: 10.1016/j.biomaterials.2012.03.027. Epub 2012 Apr 1.

PMID:
22465338
6.

Carbohydrate-functionalized nanovaccines preserve HIV-1 antigen stability and activate antigen presenting cells.

Vela Ramirez JE, Roychoudhury R, Habte HH, Cho MW, Pohl NL, Narasimhan B.

J Biomater Sci Polym Ed. 2014;25(13):1387-406. doi: 10.1080/09205063.2014.940243. Epub 2014 Jul 28.

7.

Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles.

Vela-Ramirez JE, Goodman JT, Boggiatto PM, Roychoudhury R, Pohl NL, Hostetter JM, Wannemuehler MJ, Narasimhan B.

AAPS J. 2015 Jan;17(1):256-67. doi: 10.1208/s12248-014-9699-z. Epub 2014 Nov 25.

8.

Harvesting murine alveolar macrophages and evaluating cellular activation induced by polyanhydride nanoparticles.

Chavez-Santoscoy AV, Huntimer LM, Ramer-Tait AE, Wannemuehler M, Narasimhan B.

J Vis Exp. 2012 Jun 8;(64):e3883. doi: 10.3791/3883.

9.

Activation of innate immune responses in a pathogen-mimicking manner by amphiphilic polyanhydride nanoparticle adjuvants.

Petersen LK, Ramer-Tait AE, Broderick SR, Kong CS, Ulery BD, Rajan K, Wannemuehler MJ, Narasimhan B.

Biomaterials. 2011 Oct;32(28):6815-22. doi: 10.1016/j.biomaterials.2011.05.063. Epub 2011 Jun 24.

PMID:
21703679
10.

High-throughput analysis of protein stability in polyanhydride nanoparticles.

Petersen LK, Sackett CK, Narasimhan B.

Acta Biomater. 2010 Oct;6(10):3873-81. doi: 10.1016/j.actbio.2010.04.004. Epub 2010 Apr 11.

PMID:
20388561
11.

Amphiphilic polyanhydride nanoparticles stabilize Bacillus anthracis protective antigen.

Petersen LK, Phanse Y, Ramer-Tait AE, Wannemuehler MJ, Narasimhan B.

Mol Pharm. 2012 Apr 2;9(4):874-82. doi: 10.1021/mp2004059. Epub 2012 Mar 20.

12.

A platform to screen for C-type lectin receptor-binding carbohydrates and their potential for cell-specific targeting and immune modulation.

Maglinao M, Eriksson M, Schlegel MK, Zimmermann S, Johannssen T, Götze S, Seeberger PH, Lepenies B.

J Control Release. 2014 Feb 10;175:36-42. doi: 10.1016/j.jconrel.2013.12.011. Epub 2013 Dec 22.

PMID:
24368301
13.

Toward solution-phase automated iterative synthesis: fluorous-tag assisted solution-phase synthesis of linear and branched mannose oligomers.

Jaipuri FA, Pohl NL.

Org Biomol Chem. 2008 Aug 7;6(15):2686-91. doi: 10.1039/b803451f. Epub 2008 May 16.

PMID:
18633525
14.

The effect of polyanhydride chemistry in particle-based cancer vaccines on the magnitude of the anti-tumor immune response.

Wafa EI, Geary SM, Goodman JT, Narasimhan B, Salem AK.

Acta Biomater. 2017 Mar 1;50:417-427. doi: 10.1016/j.actbio.2017.01.005. Epub 2017 Jan 4.

PMID:
28063991
15.

Polyanhydride Nanovaccines Induce Germinal Center B Cell Formation and Sustained Serum Antibody Responses.

Vela Ramirez JE, Tygrett LT, Hao J, Habte HH, Cho MW, Greenspan NS, Waldschmidt TJ, Narasimhan B.

J Biomed Nanotechnol. 2016 Jun;12(6):1303-11.

16.

Targeting C-type lectin receptors with multivalent carbohydrate ligands.

Lepenies B, Lee J, Sonkaria S.

Adv Drug Deliv Rev. 2013 Aug;65(9):1271-81. doi: 10.1016/j.addr.2013.05.007. Epub 2013 May 30. Review.

PMID:
23727341
17.

Mannosylated dextran nanoparticles: a pH-sensitive system engineered for immunomodulation through mannose targeting.

Cui L, Cohen JA, Broaders KE, Beaudette TT, Fréchet JM.

Bioconjug Chem. 2011 May 18;22(5):949-57. doi: 10.1021/bc100596w. Epub 2011 Apr 25.

PMID:
21476603
18.

Chemistry-dependent adsorption of serum proteins onto polyanhydride microparticles differentially influences dendritic cell uptake and activation.

Carrillo-Conde BR, Ramer-Tait AE, Wannemuehler MJ, Narasimhan B.

Acta Biomater. 2012 Oct;8(10):3618-28. doi: 10.1016/j.actbio.2012.06.001. Epub 2012 Jun 8.

PMID:
22684115
19.

In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model.

Silva JM, Zupancic E, Vandermeulen G, Oliveira VG, Salgado A, Videira M, Gaspar M, Graca L, Préat V, Florindo HF.

J Control Release. 2015 Jan 28;198:91-103. doi: 10.1016/j.jconrel.2014.11.033. Epub 2014 Dec 5.

PMID:
25483429
20.

Parallel synthesis and high throughput dissolution testing of biodegradable polyanhydride copolymers.

Vogel BM, Cabral JT, Eidelman N, Narasimhan B, Mallapragada SK.

J Comb Chem. 2005 Nov-Dec;7(6):921-8.

PMID:
16283803

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