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Items: 1 to 20 of 104

1.

Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2.

Kipanyula MJ, Contreras L, Zampese E, Lazzari C, Wong AK, Pizzo P, Fasolato C, Pozzan T.

Aging Cell. 2012 Oct;11(5):885-93. doi: 10.1111/j.1474-9726.2012.00858.x. Epub 2012 Aug 7.

2.

Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.

Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.

Cell Calcium. 2006 Jun;39(6):539-50. Epub 2006 Apr 18.

PMID:
16620965
3.

Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.

Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.

J Neurosci Res. 2002 Aug 15;69(4):530-9.

PMID:
12210846
4.

Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.

Siman R, Reaume AG, Savage MJ, Trusko S, Lin YG, Scott RW, Flood DG.

J Neurosci. 2000 Dec 1;20(23):8717-26.

5.

Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.

Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.

Biochemistry. 1998 Nov 24;37(47):16465-71.

PMID:
9843412
6.

Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca2+ cross-talk.

Zampese E, Fasolato C, Kipanyula MJ, Bortolozzi M, Pozzan T, Pizzo P.

Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2777-82. doi: 10.1073/pnas.1100735108. Epub 2011 Feb 1.

7.

Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice.

Lopez JR, Lyckman A, Oddo S, Laferla FM, Querfurth HW, Shtifman A.

J Neurochem. 2008 Apr;105(1):262-71. Epub 2007 Nov 16.

9.

Lack of evidence for presenilins as endoplasmic reticulum Ca2+ leak channels.

Shilling D, Mak DO, Kang DE, Foskett JK.

J Biol Chem. 2012 Mar 30;287(14):10933-44. doi: 10.1074/jbc.M111.300491. Epub 2012 Feb 6.

11.

Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis.

Sepulveda-Falla D, Barrera-Ocampo A, Hagel C, Korwitz A, Vinueza-Veloz MF, Zhou K, Schonewille M, Zhou H, Velazquez-Perez L, Rodriguez-Labrada R, Villegas A, Ferrer I, Lopera F, Langer T, De Zeeuw CI, Glatzel M.

J Clin Invest. 2014 Apr;124(4):1552-67. doi: 10.1172/JCI66407. Epub 2014 Feb 24.

12.

Enhanced caffeine-induced Ca2+ release in the 3xTg-AD mouse model of Alzheimer's disease.

Smith IF, Hitt B, Green KN, Oddo S, LaFerla FM.

J Neurochem. 2005 Sep;94(6):1711-8.

13.

Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.

Ryazantseva M, Skobeleva K, Glushankova L, Kaznacheyeva E.

J Neurochem. 2016 Mar;136(5):1085-95. doi: 10.1111/jnc.13495. Epub 2016 Jan 11.

14.

Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.

Herms J, Schneider I, Dewachter I, Caluwaerts N, Kretzschmar H, Van Leuven F.

J Biol Chem. 2003 Jan 24;278(4):2484-9. Epub 2002 Nov 12.

15.

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS.

Neuron. 1997 Oct;19(4):939-45.

16.
17.

Presenilins, the endoplasmic reticulum, and neuronal apoptosis in Alzheimer's disease.

Mattson MP, Guo Q, Furukawa K, Pedersen WA.

J Neurochem. 1998 Jan;70(1):1-14. Review.

18.

Presenilin mutations in familial Alzheimer disease and transgenic mouse models accelerate neuronal lysosomal pathology.

Cataldo AM, Peterhoff CM, Schmidt SD, Terio NB, Duff K, Beard M, Mathews PM, Nixon RA.

J Neuropathol Exp Neurol. 2004 Aug;63(8):821-30.

PMID:
15330337
19.

Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1.

Lévesque L, Annaert W, Craessaerts K, Mathews PM, Seeger M, Nixon RA, Van Leuven F, Gandy S, Westaway D, St George-Hyslop P, De Strooper B, Fraser PE.

Mol Med. 1999 Aug;5(8):542-54.

20.

The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells.

Lessard CB, Lussier MP, Cayouette S, Bourque G, Boulay G.

Cell Signal. 2005 Apr;17(4):437-45.

PMID:
15601622

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