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Items: 1 to 20 of 114


Shp2 activates Fyn and Ras to regulate RBL-2H3 mast cell activation following FcεRI aggregation.

Fang X, Lang Y, Wang Y, Mo W, Wei H, Xie J, Yu M.

PLoS One. 2012;7(7):e40566. doi: 10.1371/journal.pone.0040566. Epub 2012 Jul 10.


SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc epsilon RI-induced activation of Fyn and Erk pathways leading to TNF alpha release from bone marrow-derived mast cells.

McPherson VA, Sharma N, Everingham S, Smith J, Zhu HH, Feng GS, Craig AW.

J Immunol. 2009 Oct 15;183(8):4940-7. doi: 10.4049/jimmunol.0900702. Epub 2009 Sep 28.


An involvement of neurokinin-1 receptor in FcεRΙ-mediated RBL-2H3 mast cell activation.

Fang X, Hu H, Xie J, Zhu H, Zhang D, Mo W, Zhang R, Yu M.

Inflamm Res. 2012 Nov;61(11):1257-63. doi: 10.1007/s00011-012-0523-x. Epub 2012 Jul 21.


Signal regulatory protein α negatively regulates mast-cell activation following FcεRI aggregation.

Pan YF, Dong LW, Wang M, Yang GZ, Zhang J, Li SX, Zhang B, Yang C, Li Z, Tan YX, Wang HY.

Eur J Immunol. 2013 Jun;43(6):1598-607. doi: 10.1002/eji.201243031. Epub 2013 Apr 17.


PTPalpha activates Lyn and Fyn and suppresses Hck to negatively regulate FcepsilonRI-dependent mast cell activation and allergic responses.

Samayawardhena LA, Pallen CJ.

J Immunol. 2010 Nov 15;185(10):5993-6002. doi: 10.4049/jimmunol.1001261. Epub 2010 Oct 13.


Regulation of mast cell signaling through high-affinity IgE receptor by CD45 protein tyrosine phosphatase.

Murakami K, Sato S, Nagasawa S, Yamashita T.

Int Immunol. 2000 Feb;12(2):169-76.


MEK and ERK activation in ras-disabled RBL-2H3 mast cells and novel roles for geranylgeranylated and farnesylated proteins in Fc epsilonRI-mediated signaling.

Graham TE, Pfeiffer JR, Lee RJ, Kusewitt DF, Martinez AM, Foutz T, Wilson BS, Oliver JM.

J Immunol. 1998 Dec 15;161(12):6733-44.


Regulation of the tyrosine phosphorylation of Phospholipid Scramblase 1 in mast cells that are stimulated through the high-affinity IgE receptor.

Kassas A, Moura IC, Yamashita Y, Scheffel J, Guérin-Marchand C, Blank U, Sims PJ, Wiedmer T, Monteiro RC, Rivera J, Charles N, Benhamou M.

PLoS One. 2014 Oct 7;9(10):e109800. doi: 10.1371/journal.pone.0109800. eCollection 2014.


Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells.

Kato N, Nakanishi M, Hirashima N.

J Immunol. 2006 Jul 1;177(1):147-54.


Protein tyrosine phosphatase-PEST (PTP-PEST) regulates mast cell-activating signals in PTP activity-dependent and -independent manners.

Motohashi S, Koizumi K, Honda R, Maruyama A, Palmer HE, Mashima K.

Cell Immunol. 2014 May-Jun;289(1-2):128-34. doi: 10.1016/j.cellimm.2014.04.003. Epub 2014 Apr 13.


Phospholipid scramblase 1 modulates a selected set of IgE receptor-mediated mast cell responses through LAT-dependent pathway.

Amir-Moazami O, Alexia C, Charles N, Launay P, Monteiro RC, Benhamou M.

J Biol Chem. 2008 Sep 12;283(37):25514-23. doi: 10.1074/jbc.M705320200. Epub 2008 Jun 25.


Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.

Udell CM, Samayawardhena LA, Kawakami Y, Kawakami T, Craig AW.

J Biol Chem. 2006 Jul 28;281(30):20949-57. Epub 2006 May 26.


PICOT, protein kinase C theta-interacting protein, is a novel regulator of FcepsilonRI-mediated mast cell activation.

Kato N, Motohashi S, Okada T, Ozawa T, Mashima K.

Cell Immunol. 2008 Jan;251(1):62-7. doi: 10.1016/j.cellimm.2008.04.005. Epub 2008 May 13.


Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells.

Sada K, Miah SM, Maeno K, Kyo S, Qu X, Yamamura H.

Blood. 2002 Sep 15;100(6):2138-44.


C3a-derived peptide binds to the type I FcepsilonR and inhibits proximal-coupling signal processes and cytokine secretion by mast cells.

Péterfy H, Tóth G, Pecht I, Erdei A.

Int Immunol. 2008 Oct;20(10):1239-45. doi: 10.1093/intimm/dxn083. Epub 2008 Jul 24.


Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor.

Samayawardhena LA, Hu J, Stein PL, Craig AW.

Cell Signal. 2006 Sep;18(9):1447-54. Epub 2006 Jan 25.


Activation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and Fgr.

Choi WS, Hiragun T, Lee JH, Kim YM, Kim HP, Chahdi A, Her E, Han JW, Beaven MA.

Mol Cell Biol. 2004 Aug;24(16):6980-92.


Fyn kinase regulates type II PtdIns 4-kinases in RBL 2H3 cells.

Bojjireddy N, Sinha RK, Subrahmanyam G.

Mol Cell Biochem. 2014 Feb;387(1-2):63-70. doi: 10.1007/s11010-013-1871-8. Epub 2013 Oct 31.


Association of 3BP2 with SHP-1 regulates SHP-1-mediated production of TNF-α in RBL-2H3 cells.

Chihara K, Nakashima K, Takeuchi K, Sada K.

Genes Cells. 2011 Dec;16(12):1133-45. doi: 10.1111/j.1365-2443.2011.01557.x. Epub 2011 Nov 13.

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