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Items: 1 to 20 of 109

1.

Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells.

Peters HL, Tuli A, Wang X, Liu C, Pan Z, Ouellette MM, Hollingsworth MA, Macdonald RG, Solheim JC.

Int J Oncol. 2012 Oct;41(4):1464-74. doi: 10.3892/ijo.2012.1553. Epub 2012 Jul 13.

2.

Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.

Hogl S, Kuhn PH, Colombo A, Lichtenthaler SF.

PLoS One. 2011;6(6):e21337. doi: 10.1371/journal.pone.0021337. Epub 2011 Jun 17.

3.

Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases.

Endres K, Postina R, Schroeder A, Mueller U, Fahrenholz F.

FEBS J. 2005 Nov;272(22):5808-20.

4.

Accumulation of the amyloid precursor-like protein APLP2 and reduction of APLP1 in retinoic acid-differentiated human neuroblastoma cells upon curcumin-induced neurite retraction.

Adlerz L, Beckman M, Holback S, Tehranian R, Cortés Toro V, Iverfeldt K.

Brain Res Mol Brain Res. 2003 Nov 6;119(1):62-72.

PMID:
14597230
5.

beta-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins.

Sala Frigerio C, Fadeeva JV, Minogue AM, Citron M, Van Leuven F, Staufenbiel M, Paganetti P, Selkoe DJ, Walsh DM.

FEBS J. 2010 Mar;277(6):1503-18. doi: 10.1111/j.1742-4658.2010.07579.x. Epub 2010 Feb 15.

6.

Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis.

Pandey P, Rachagani S, Das S, Seshacharyulu P, Sheinin Y, Naslavsky N, Pan Z, Smith BL, Peters HL, Radhakrishnan P, McKenna NR, Giridharan SS, Haridas D, Kaur S, Hollingsworth MA, MacDonald RG, Meza JL, Caplan S, Batra SK, Solheim JC.

Oncotarget. 2015 Feb 10;6(4):2064-75.

7.

Inhibition of amyloid precursor protein processing enhances gemcitabine-mediated cytotoxicity in pancreatic cancer cells.

Woods NK, Padmanabhan J.

J Biol Chem. 2013 Oct 18;288(42):30114-24. doi: 10.1074/jbc.M113.459255. Epub 2013 Sep 10.

8.
9.

An NSAID-like compound, FT-9, preferentially inhibits gamma-secretase cleavage of the amyloid precursor protein compared to its effect on amyloid precursor-like protein 1.

Sala Frigerio C, Kukar TL, Fauq A, Engel PC, Golde TE, Walsh DM.

Biochemistry. 2009 Nov 24;48(46):10894-904. doi: 10.1021/bi901237k.

10.

Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein.

Venkataramani V, Rossner C, Iffland L, Schweyer S, Tamboli IY, Walter J, Wirths O, Bayer TA.

J Biol Chem. 2010 Apr 2;285(14):10678-89. doi: 10.1074/jbc.M109.057836. Epub 2010 Feb 9.

11.

Insulin-like growth factor-1 (IGF-1)-induced processing of amyloid-beta precursor protein (APP) and APP-like protein 2 is mediated by different metalloproteinases.

Jacobsen KT, Adlerz L, Multhaup G, Iverfeldt K.

J Biol Chem. 2010 Apr 2;285(14):10223-31. doi: 10.1074/jbc.M109.038224. Epub 2010 Feb 5.

12.

Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission.

Schrenk-Siemens K, Perez-Alcala S, Richter J, Lacroix E, Rahuel J, Korte M, Müller U, Barde YA, Bibel M.

Stem Cells. 2008 Aug;26(8):2153-63. doi: 10.1634/stemcells.2008-0010. Epub 2008 Jun 5.

13.

Similar alternative splicing of a non-homologous domain in beta A4-amyloid protein precursor-like proteins.

Sandbrink R, Masters CL, Beyreuther K.

J Biol Chem. 1994 May 13;269(19):14227-34.

14.

APP gene family. Alternative splicing generates functionally related isoforms.

Sandbrink R, Masters CL, Beyreuther K.

Ann N Y Acad Sci. 1996 Jan 17;777:281-7.

PMID:
8624099
15.

Amyloid precursor-like protein 1 (APLP1) exhibits stronger zinc-dependent neuronal adhesion than amyloid precursor protein and APLP2.

Mayer MC, Schauenburg L, Thompson-Steckel G, Dunsing V, Kaden D, Voigt P, Schaefer M, Chiantia S, Kennedy TE, Multhaup G.

J Neurochem. 2016 Apr;137(2):266-76. doi: 10.1111/jnc.13540. Epub 2016 Mar 7.

17.

Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members.

Heber S, Herms J, Gajic V, Hainfellner J, Aguzzi A, Rülicke T, von Kretzschmar H, von Koch C, Sisodia S, Tremml P, Lipp HP, Wolfer DP, Müller U.

J Neurosci. 2000 Nov 1;20(21):7951-63.

18.

MicroRNA-153 negatively regulates the expression of amyloid precursor protein and amyloid precursor-like protein 2.

Liang C, Zhu H, Xu Y, Huang L, Ma C, Deng W, Liu Y, Qin C.

Brain Res. 2012 May 21;1455:103-13. doi: 10.1016/j.brainres.2011.10.051. Epub 2011 Nov 4.

PMID:
22510281
19.

A disintegrin and metalloprotease 10 activity sheds the ectodomain of the amyloid precursor-like protein 2 and regulates protein expression in proximal tubule cells.

Cong R, Li Y, Biemesderfer D.

Am J Physiol Cell Physiol. 2011 Jun;300(6):C1366-74. doi: 10.1152/ajpcell.00451.2010. Epub 2011 Feb 16.

20.

Identification and expression of the first nonmammalian amyloid-beta precursor-like protein APLP2 in the amphibian Xenopus laevis.

Collin RW, van Strien D, Leunissen JA, Martens GJ.

Eur J Biochem. 2004 May;271(10):1906-12.

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