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Items: 1 to 20 of 156

1.

Protection of blood retinal barrier and systemic vasculature by insulin-like growth factor binding protein-3.

Jarajapu YP, Cai J, Yan Y, Li Calzi S, Kielczewski JL, Hu P, Shaw LC, Firth SM, Chan-Ling T, Boulton ME, Baxter RC, Grant MB.

PLoS One. 2012;7(7):e39398. doi: 10.1371/journal.pone.0039398. Epub 2012 Jul 6.

2.

Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation.

Kielczewski JL, Jarajapu YP, McFarland EL, Cai J, Afzal A, Li Calzi S, Chang KH, Lydic T, Shaw LC, Busik J, Hughes J, Cardounel AJ, Wilson K, Lyons TJ, Boulton ME, Mames RN, Chan-Ling T, Grant MB.

Circ Res. 2009 Oct 23;105(9):897-905. doi: 10.1161/CIRCRESAHA.109.199059. Epub 2009 Sep 17.

3.

Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).

Kielczewski JL, Li Calzi S, Shaw LC, Cai J, Qi X, Ruan Q, Wu L, Liu L, Hu P, Chan-Ling T, Mames RN, Firth S, Baxter RC, Turowski P, Busik JV, Boulton ME, Grant MB.

Invest Ophthalmol Vis Sci. 2011 Oct 21;52(11):8278-86. doi: 10.1167/iovs.11-8167.

4.

IGFBP-3 reduces eNOS and PKCzeta phosphorylation, leading to lowered VEGF levels.

Zhang Q, Jiang Y, Steinle JJ.

Mol Vis. 2015 May 22;21:604-11. eCollection 2015.

5.

Insulin stabilizes microvascular endothelial barrier function via phosphatidylinositol 3-kinase/Akt-mediated Rac1 activation.

Gündüz D, Thom J, Hussain I, Lopez D, Härtel FV, Erdogan A, Grebe M, Sedding D, Piper HM, Tillmanns H, Noll T, Aslam M.

Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1237-45. doi: 10.1161/ATVBAHA.110.203901. Epub 2010 Mar 25.

6.

Sphingosine-1-phosphate receptor 2 protects against anaphylactic shock through suppression of endothelial nitric oxide synthase in mice.

Cui H, Okamoto Y, Yoshioka K, Du W, Takuwa N, Zhang W, Asano M, Shibamoto T, Takuwa Y.

J Allergy Clin Immunol. 2013 Nov;132(5):1205-1214.e9. doi: 10.1016/j.jaci.2013.07.026. Epub 2013 Sep 8.

PMID:
24021572
7.

Depolarization of mitochondria in endothelial cells promotes cerebral artery vasodilation by activation of nitric oxide synthase.

Katakam PV, Wappler EA, Katz PS, Rutkai I, Institoris A, Domoki F, Gáspár T, Grovenburg SM, Snipes JA, Busija DW.

Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):752-9. doi: 10.1161/ATVBAHA.112.300560. Epub 2013 Jan 17.

8.

Specific activation of insulin-like growth factor-1 receptor by ginsenoside Rg5 promotes angiogenesis and vasorelaxation.

Cho YL, Hur SM, Kim JY, Kim JH, Lee DK, Choe J, Won MH, Ha KS, Jeoung D, Han S, Ryoo S, Lee H, Min JK, Kwon YG, Kim DH, Kim YM.

J Biol Chem. 2015 Jan 2;290(1):467-77. doi: 10.1074/jbc.M114.603142. Epub 2014 Nov 12.

9.

Propionyl-L-carnitine induces eNOS activation and nitric oxide synthesis in endothelial cells via PI3 and Akt kinases.

Ning WH, Zhao K.

Vascul Pharmacol. 2013 Sep-Oct;59(3-4):76-82. doi: 10.1016/j.vph.2013.07.001. Epub 2013 Jul 12.

PMID:
23850990
10.

Beneficial effects of the Src inhibitor, dasatinib, on breakdown of the blood-retinal barrier.

Kim SR, Suh W.

Arch Pharm Res. 2017 Feb;40(2):197-203. doi: 10.1007/s12272-016-0872-z. Epub 2016 Dec 17.

PMID:
27988882
11.

[Inhibitory effect of insulin-like growth factor binding protein-related protein 1 on retinal angiogenesis via ERK signaling pathway].

Zhang P, Wang H, Cao H, Xu X, Sun T.

Zhonghua Yan Ke Za Zhi. 2017 Mar 11;53(3):207-211. doi: 10.3760/cma.j.issn.0412-4081.2017.03.012. Chinese.

PMID:
28316197
13.

EphrinA1 inhibits vascular endothelial growth factor-induced intracellular signaling and suppresses retinal neovascularization and blood-retinal barrier breakdown.

Ojima T, Takagi H, Suzuma K, Oh H, Suzuma I, Ohashi H, Watanabe D, Suganami E, Murakami T, Kurimoto M, Honda Y, Yoshimura N.

Am J Pathol. 2006 Jan;168(1):331-9.

14.

Insulin-like growth factor binding protein-3 induces angiogenesis through IGF-I- and SphK1-dependent mechanisms.

Granata R, Trovato L, Lupia E, Sala G, Settanni F, Camussi G, Ghidoni R, Ghigo E.

J Thromb Haemost. 2007 Apr;5(4):835-45. Epub 2007 Feb 9.

15.

Preserved insulin vasorelaxation and up-regulation of the Akt/eNOS pathway in coronary arteries from insulin resistant obese Zucker rats.

Contreras C, Sánchez A, García-Sacristán A, Martínez MC, Andriantsitohaina R, Prieto D.

Atherosclerosis. 2011 Aug;217(2):331-9. doi: 10.1016/j.atherosclerosis.2011.03.036. Epub 2011 Apr 5.

PMID:
21514935
16.

IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis.

Zhang C, Lu L, Li Y, Wang X, Zhou J, Liu Y, Fu P, Gallicchio MA, Bach LA, Duan C.

Int J Cancer. 2012 May 1;130(9):2003-12. doi: 10.1002/ijc.26201. Epub 2011 Aug 5.

18.

CCN1 acutely increases nitric oxide production via integrin αvβ3-Akt-S6K-phosphorylation of endothelial nitric oxide synthase at the serine 1177 signaling axis.

Hwang S, Lee HJ, Kim G, Won KJ, Park YS, Jo I.

Free Radic Biol Med. 2015 Dec;89:229-40. doi: 10.1016/j.freeradbiomed.2015.08.005. Epub 2015 Sep 21.

PMID:
26393424
19.

Exendin-4 alleviates retinal vascular leakage by protecting the blood-retinal barrier and reducing retinal vascular permeability in diabetic Goto-Kakizaki rats.

Fan Y, Liu K, Wang Q, Ruan Y, Ye W, Zhang Y.

Exp Eye Res. 2014 Oct;127:104-16. doi: 10.1016/j.exer.2014.05.004. Epub 2014 Jun 6.

PMID:
24910901
20.

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