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Items: 1 to 20 of 83

1.

Anti-diabetic and hypolipidemic effects of Sargassum yezoense in db/db mice.

Kim SN, Lee W, Bae GU, Kim YK.

Biochem Biophys Res Commun. 2012 Aug 10;424(4):675-80. doi: 10.1016/j.bbrc.2012.07.005. Epub 2012 Jul 10.

PMID:
22789850
2.

Sargaquinoic acid and sargahydroquinoic acid from Sargassum yezoense stimulate adipocyte differentiation through PPARalpha/gamma activation in 3T3-L1 cells.

Kim SN, Choi HY, Lee W, Park GM, Shin WS, Kim YK.

FEBS Lett. 2008 Oct 15;582(23-24):3465-72. doi: 10.1016/j.febslet.2008.09.011. Epub 2008 Sep 17.

3.

A newly identified CG301269 improves lipid and glucose metabolism without body weight gain through activation of peroxisome proliferator-activated receptor alpha and gamma.

Jeong HW, Lee JW, Kim WS, Choe SS, Kim KH, Park HS, Shin HJ, Lee GY, Shin D, Lee H, Lee JH, Choi EB, Lee HK, Chung H, Park SB, Park KS, Kim HS, Ro S, Kim JB.

Diabetes. 2011 Feb;60(2):496-506. doi: 10.2337/db09-1145.

4.

Anti-diabetic effect of amorphastilbol through PPARα/γ dual activation in db/db mice.

Lee W, Ham J, Kwon HC, Kim YK, Kim SN.

Biochem Biophys Res Commun. 2013 Mar 1;432(1):73-9. doi: 10.1016/j.bbrc.2013.01.083. Epub 2013 Jan 29.

PMID:
23376064
5.

Blood glucose-lowering nuclear receptor agonists only partially normalize hepatic gene expression in db/db mice.

Loffler M, Bilban M, Reimers M, Waldhäusl W, Stulnig TM.

J Pharmacol Exp Ther. 2006 Feb;316(2):797-804. Epub 2005 Oct 31.

6.

Effect of saponins from Helicteres isora on lipid and glucose metabolism regulating genes expression.

Bhavsar SK, Singh S, Giri S, Jain MR, Santani DD.

J Ethnopharmacol. 2009 Jul 30;124(3):426-33. doi: 10.1016/j.jep.2009.05.041. Epub 2009 Jun 6.

PMID:
19505560
7.

Evaluation of loganin, iridoid glycoside from Corni Fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db mice.

Yamabe N, Noh JS, Park CH, Kang KS, Shibahara N, Tanaka T, Yokozawa T.

Eur J Pharmacol. 2010 Dec 1;648(1-3):179-87. doi: 10.1016/j.ejphar.2010.08.044. Epub 2010 Sep 15.

PMID:
20826139
8.

Antidiabetic and hypolipidemic effects of a novel dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist, E3030, in db/db mice and beagle dogs.

Kasai S, Inoue T, Yoshitomi H, Hihara T, Matsuura F, Harada H, Shinoda M, Tanaka I.

J Pharmacol Sci. 2008 Sep;108(1):40-8. Epub 2008 Sep 6.

9.

P633H, a novel dual agonist at peroxisome proliferator-activated receptors alpha and gamma, with different anti-diabetic effects in db/db and KK-Ay mice.

Chen W, Zhou XB, Liu HY, Xu C, Wang LL, Li S.

Br J Pharmacol. 2009 Jul;157(5):724-35. doi: 10.1111/j.1476-5381.2009.00231.x. Epub 2009 May 5.

10.

Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice.

Park MH, Park JY, Lee HJ, Kim DH, Park D, Jeong HO, Park CH, Chun P, Moon HR, Chung HY.

PLoS One. 2013 Nov 14;8(11):e78815. doi: 10.1371/journal.pone.0078815. eCollection 2013.

11.
12.

18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.

Anandharajan R, Sayyed SG, Doshi LS, Dixit P, Chandak PG, Dixit AV, Brahma MK, Deshmukh NJ, Gupte R, Damre A, Suthar J, Padigaru M, Sharma SD, Nemmani KV.

Metabolism. 2009 Oct;58(10):1503-16. doi: 10.1016/j.metabol.2009.04.036. Epub 2009 Jul 15.

13.

Antihyperglycemic and antihyperlipidemic action of Cinnamomi Cassiae (Cinnamon bark) extract in C57BL/Ks db/db mice.

Kim SH, Choung SY.

Arch Pharm Res. 2010 Feb;33(2):325-33. doi: 10.1007/s12272-010-0219-0. Epub 2010 Feb 24.

PMID:
20195835
14.

Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice.

Cha DR, Zhang X, Zhang Y, Wu J, Su D, Han JY, Fang X, Yu B, Breyer MD, Guan Y.

Diabetes. 2007 Aug;56(8):2036-45. Epub 2007 May 29.

15.

A nonthiazolidinedione peroxisome proliferator-activated receptor α/γ dual agonist CG301360 alleviates insulin resistance and lipid dysregulation in db/db mice.

Jeong HW, Lee JW, Kim WS, Choe SS, Shin HJ, Lee GY, Shin D, Lee JH, Choi EB, Lee HK, Yon GH, Cho B, Kim HR, Choi SH, Chung YS, Park SB, Chung H, Ro S, Kim JB.

Mol Pharmacol. 2010 Nov;78(5):877-85. doi: 10.1124/mol.110.065748. Epub 2010 Aug 19.

16.

Effect of Chinese prescription Kangen-karyu on lipid metabolism in type 2 diabetic db/db mice.

Yamabe N, Kim HY, Kang KS, Zhao Q, Matsumoto K, Yokozawa T.

J Ethnopharmacol. 2010 Jun 16;129(3):299-305. doi: 10.1016/j.jep.2010.03.032. Epub 2010 Apr 2.

PMID:
20363309
17.

Novel anti-diabetic effect of SCM-198 via inhibiting the hepatic NF-κB pathway in db/db mice.

Huang H, Xin H, Liu X, Xu Y, Wen D, Zhang Y, Zhu YZ.

Biosci Rep. 2012 Apr 1;32(2):185-95. doi: 10.1042/BSR20110017.

PMID:
21859425
18.

Genistein and daidzein modulate hepatic glucose and lipid regulating enzyme activities in C57BL/KsJ-db/db mice.

Ae Park S, Choi MS, Cho SY, Seo JS, Jung UJ, Kim MJ, Sung MK, Park YB, Lee MK.

Life Sci. 2006 Aug 15;79(12):1207-13. Epub 2006 Mar 27.

PMID:
16647724
19.

Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus.

Bajaj M, Suraamornkul S, Hardies LJ, Glass L, Musi N, DeFronzo RA.

Diabetologia. 2007 Aug;50(8):1723-31. Epub 2007 May 23.

PMID:
17520238
20.

Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet.

Kang JH, Goto T, Han IS, Kawada T, Kim YM, Yu R.

Obesity (Silver Spring). 2010 Apr;18(4):780-7. doi: 10.1038/oby.2009.301. Epub 2009 Oct 1.

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