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Items: 1 to 20 of 77

1.

STK25 protein mediates TrkA and CCM2 protein-dependent death in pediatric tumor cells of neural origin.

Costa B, Kean MJ, Ast V, Knight JD, Mett A, Levy Z, Ceccarelli DF, Badillo BG, Eils R, König R, Gingras AC, Fainzilber M.

J Biol Chem. 2012 Aug 24;287(35):29285-9. doi: 10.1074/jbc.C112.345397. Epub 2012 Jul 10.

2.

CCM2 mediates death signaling by the TrkA receptor tyrosine kinase.

Harel L, Costa B, Tcherpakov M, Zapatka M, Oberthuer A, Hansford LM, Vojvodic M, Levy Z, Chen ZY, Lee FS, Avigad S, Yaniv I, Shi L, Eils R, Fischer M, Brors B, Kaplan DR, Fainzilber M.

Neuron. 2009 Sep 10;63(5):585-91. doi: 10.1016/j.neuron.2009.08.020.

3.

CCM3 interacts with CCM2 indicating common pathogenesis for cerebral cavernous malformations.

Voss K, Stahl S, Schleider E, Ullrich S, Nickel J, Mueller TD, Felbor U.

Neurogenetics. 2007 Nov;8(4):249-56. Epub 2007 Jul 27.

PMID:
17657516
4.

CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations.

Zheng X, Xu C, Di Lorenzo A, Kleaveland B, Zou Z, Seiler C, Chen M, Cheng L, Xiao J, He J, Pack MA, Sessa WC, Kahn ML.

J Clin Invest. 2010 Aug;120(8):2795-804. doi: 10.1172/JCI39679. Epub 2010 Jul 1.

5.

Live or let die: CCM2 provides the link.

Gruber-Olipitz M, Segal RA.

Neuron. 2009 Sep 10;63(5):559-60. doi: 10.1016/j.neuron.2009.08.030.

6.

PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress.

Zhang H, Ma X, Deng X, Chen Y, Mo X, Zhang Y, Zhao H, Ma D.

Front Biosci (Landmark Ed). 2012 Jun 1;17:2295-305.

PMID:
22652780
7.

Dlk/ZIP kinase-induced apoptosis in human medulloblastoma cells: requirement of the mitochondrial apoptosis pathway.

Kögel D, Reimertz C, Mech P, Poppe M, Frühwald MC, Engemann H, Scheidtmann KH, Prehn JH.

Br J Cancer. 2001 Nov 30;85(11):1801-8.

8.

Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein.

Voss K, Stahl S, Hogan BM, Reinders J, Schleider E, Schulte-Merker S, Felbor U.

Hum Mutat. 2009 Jun;30(6):1003-11. doi: 10.1002/humu.20996.

PMID:
19370760
9.

A novel apoptotic pathway induced by nerve growth factor-mediated TrkA activation in medulloblastoma.

Chou TT, Trojanowski JQ, Lee VM.

J Biol Chem. 2000 Jan 7;275(1):565-70.

10.

Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.

Culmsee C, Gerling N, Lehmann M, Nikolova-Karakashian M, Prehn JH, Mattson MP, Krieglstein J.

Neuroscience. 2002;115(4):1089-108.

PMID:
12453482
11.

Zhangfei induces the expression of the nerve growth factor receptor, trkA, in medulloblastoma cells and causes their differentiation or apoptosis.

Valderrama X, Rapin N, Verge VM, Misra V.

J Neurooncol. 2009 Jan;91(1):7-17. doi: 10.1007/s11060-008-9682-6. Epub 2008 Aug 22.

PMID:
18719857
12.

GIPC and GAIP form a complex with TrkA: a putative link between G protein and receptor tyrosine kinase pathways.

Lou X, Yano H, Lee F, Chao MV, Farquhar MG.

Mol Biol Cell. 2001 Mar;12(3):615-27.

13.
14.

SHP-1 negatively regulates neuronal survival by functioning as a TrkA phosphatase.

Marsh HN, Dubreuil CI, Quevedo C, Lee A, Majdan M, Walsh GS, Hausdorff S, Said FA, Zoueva O, Kozlowski M, Siminovitch K, Neel BG, Miller FD, Kaplan DR.

J Cell Biol. 2003 Dec 8;163(5):999-1010.

15.

Nerve growth factor induces apoptosis in human medulloblastoma cell lines that express TrkA receptors.

Muragaki Y, Chou TT, Kaplan DR, Trojanowski JQ, Lee VM.

J Neurosci. 1997 Jan 15;17(2):530-42.

16.
17.

Acute inactivation of the serine-threonine kinase Stk25 disrupts neuronal migration.

Matsuki T, Chen J, Howell BW.

Neural Dev. 2013 Nov 13;8:21. doi: 10.1186/1749-8104-8-21.

18.

On the death Trk.

Harel L, Costa B, Fainzilber M.

Dev Neurobiol. 2010 Apr;70(5):298-303. doi: 10.1002/dneu.20769. Review.

19.

Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle.

Nerstedt A, Cansby E, Andersson CX, Laakso M, Stančáková A, Blüher M, Smith U, Mahlapuu M.

Diabetologia. 2012 Jun;55(6):1797-807. doi: 10.1007/s00125-012-2511-7. Epub 2012 Mar 4.

PMID:
22391949
20.

Hepatocyte growth factor enhances death receptor-induced apoptosis by up-regulating DR5.

Li Y, Fan X, Goodwin CR, Laterra J, Xia S.

BMC Cancer. 2008 Nov 7;8:325. doi: 10.1186/1471-2407-8-325.

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