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Items: 1 to 20 of 87

1.

Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway.

Zhuang G, Wu X, Jiang Z, Kasman I, Yao J, Guan Y, Oeh J, Modrusan Z, Bais C, Sampath D, Ferrara N.

EMBO J. 2012 Aug 29;31(17):3513-23. doi: 10.1038/emboj.2012.183.

2.

microRNA-128 plays a critical role in human non-small cell lung cancer tumourigenesis, angiogenesis and lymphangiogenesis by directly targeting vascular endothelial growth factor-C.

Hu J, Cheng Y, Li Y, Jin Z, Pan Y, Liu G, Fu S, Zhang Y, Feng K, Feng Y.

Eur J Cancer. 2014 Sep;50(13):2336-50. doi: 10.1016/j.ejca.2014.06.005.

PMID:
25001183
3.

Inhibition of STAT3 signaling pathway by nitidine chloride suppressed the angiogenesis and growth of human gastric cancer.

Chen J, Wang J, Lin L, He L, Wu Y, Zhang L, Yi Z, Chen Y, Pang X, Liu M.

Mol Cancer Ther. 2012 Feb;11(2):277-87. doi: 10.1158/1535-7163.MCT-11-0648.

4.

Anti-angiogenic activity of thienopyridine derivative LCB03-0110 by targeting VEGFR-2 and JAK/STAT3 Signalling.

Kim BH, Lee Y, Yoo H, Cui M, Lee S, Kim SY, Cho JU, Lee H, Yang BS, Kwon YG, Choi S, Kim TY.

Exp Dermatol. 2015 Jul;24(7):503-9. doi: 10.1111/exd.12698.

PMID:
25808463
5.

Colorectal cancer cell-derived microvesicles containing microRNA-1246 promote angiogenesis by activating Smad 1/5/8 signaling elicited by PML down-regulation in endothelial cells.

Yamada N, Tsujimura N, Kumazaki M, Shinohara H, Taniguchi K, Nakagawa Y, Naoe T, Akao Y.

Biochim Biophys Acta. 2014 Nov;1839(11):1256-72. doi: 10.1016/j.bbagrm.2014.09.002.

PMID:
25218966
6.

Calpastatin counteracts pathological angiogenesis by inhibiting suppressor of cytokine signaling 3 degradation in vascular endothelial cells.

Miyazaki T, Taketomi Y, Saito Y, Hosono T, Lei XF, Kim-Kaneyama JR, Arata S, Takahashi H, Murakami M, Miyazaki A.

Circ Res. 2015 Mar 27;116(7):1170-81. doi: 10.1161/CIRCRESAHA.116.305363.

7.

Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway.

Senggunprai L, Kukongviriyapan V, Prawan A, Kukongviriyapan U.

Phytother Res. 2014 Jun;28(6):841-8. doi: 10.1002/ptr.5061.

PMID:
24038588
8.

STAT3-targeting RNA interference inhibits pancreatic cancer angiogenesis in vitro and in vivo.

Huang C, Jiang T, Zhu L, Liu J, Cao J, Huang KJ, Qiu ZJ.

Int J Oncol. 2011 Jun;38(6):1637-44. doi: 10.3892/ijo.2011.1000.

PMID:
21479358
9.

Mmu-miR-351 attenuates the survival of cardiac arterial endothelial cells through targeting STAT3 in the atherosclerotic mice.

Zhang Y, Liu Y, Zhang H, Wang M, Zhang J.

Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):300-5. doi: 10.1016/j.bbrc.2015.10.108.

PMID:
26505789
10.

Microvesicle-mediated transfer of microRNA-150 from monocytes to endothelial cells promotes angiogenesis.

Li J, Zhang Y, Liu Y, Dai X, Li W, Cai X, Yin Y, Wang Q, Xue Y, Wang C, Li D, Hou D, Jiang X, Zhang J, Zen K, Chen X, Zhang CY.

J Biol Chem. 2013 Aug 9;288(32):23586-96. doi: 10.1074/jbc.M113.489302.

11.

An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.

Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C.

PLoS One. 2015 May 8;10(5):e0126159. doi: 10.1371/journal.pone.0126159.

12.

Involvement of a JAK/STAT pathway inhibitor: cytokine inducible SH2 containing protein in breast cancer.

Borg├ęs S, Moudilou E, Vouyovitch C, Chiesa J, Lobie P, Mertani H, Raccurt M.

Adv Exp Med Biol. 2008;617:321-9. doi: 10.1007/978-0-387-69080-3_30.

PMID:
18497055
13.

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells.

Png KJ, Halberg N, Yoshida M, Tavazoie SF.

Nature. 2011 Dec 14;481(7380):190-4. doi: 10.1038/nature10661.

PMID:
22170610
14.

Plumbagin inhibits tumour angiogenesis and tumour growth through the Ras signalling pathway following activation of the VEGF receptor-2.

Lai L, Liu J, Zhai D, Lin Q, He L, Dong Y, Zhang J, Lu B, Chen Y, Yi Z, Liu M.

Br J Pharmacol. 2012 Feb;165(4b):1084-96. doi: 10.1111/j.1476-5381.2011.01532.x.

15.

miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2-STAT3 signaling.

Miao L, Liu K, Xie M, Xing Y, Xi T.

Cancer Immunol Immunother. 2014 Jul;63(7):699-711. doi: 10.1007/s00262-014-1550-y.

PMID:
24718681
16.

JAK/STAT/SOCS-signaling pathway and colon and rectal cancer.

Slattery ML, Lundgreen A, Kadlubar SA, Bondurant KL, Wolff RK.

Mol Carcinog. 2013 Feb;52(2):155-66. doi: 10.1002/mc.21841.

17.

CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes.

Migita K, Komori A, Torigoshi T, Maeda Y, Izumi Y, Jiuchi Y, Miyashita T, Nakamura M, Motokawa S, Ishibashi H.

Arthritis Res Ther. 2011 May 6;13(3):R72. doi: 10.1186/ar3333.

18.

Tumoricidal effects of the JAK inhibitor Ruxolitinib (INC424) on hepatocellular carcinoma in vitro.

Wilson GS, Tian A, Hebbard L, Duan W, George J, Li X, Qiao L.

Cancer Lett. 2013 Dec 1;341(2):224-30. doi: 10.1016/j.canlet.2013.08.009.

PMID:
23941832
19.

Basic fibroblast growth factor induces VEGF expression in chondrosarcoma cells and subsequently promotes endothelial progenitor cell-primed angiogenesis.

Tzeng HE, Chen PC, Lin KW, Lin CY, Tsai CH, Han SM, Teng CL, Hwang WL, Wang SW, Tang CH.

Clin Sci (Lond). 2015 Jul;129(2):147-58. doi: 10.1042/CS20140390.

PMID:
25735814
20.

Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480.

Xin H, Herrmann A, Reckamp K, Zhang W, Pal S, Hedvat M, Zhang C, Liang W, Scuto A, Weng S, Morosini D, Cao ZA, Zinda M, Figlin R, Huszar D, Jove R, Yu H.

Cancer Res. 2011 Nov 1;71(21):6601-10. doi: 10.1158/0008-5472.CAN-11-1217.

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