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Items: 1 to 20 of 103


Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.

McLaren CE, McLachlan S, Garner CP, Vulpe CD, Gordeuk VR, Eckfeldt JH, Adams PC, Acton RT, Murray JA, Leiendecker-Foster C, Snively BM, Barcellos LF, Cook JD, McLaren GD.

PLoS One. 2012;7(6):e38339. doi: 10.1371/journal.pone.0038339. Epub 2012 Jun 22.


Geographic and racial/ethnic differences in HFE mutation frequencies in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.

Acton RT, Barton JC, Snively BM, McLaren CE, Adams PC, Harris EL, Speechley MR, McLaren GD, Dawkins FW, Leiendecker-Foster C, Holup JL, Balasubramanyam A; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Ethn Dis. 2006 Autumn;16(4):815-21.


Genome-wide association study identifies genetic loci associated with iron deficiency.

McLaren CE, Garner CP, Constantine CC, McLachlan S, Vulpe CD, Snively BM, Gordeuk VR, Nickerson DA, Cook JD, Leiendecker-Foster C, Beckman KB, Eckfeldt JH, Barcellos LF, Murray JA, Adams PC, Acton RT, Killeen AA, McLaren GD.

PLoS One. 2011 Mar 31;6(3):e17390. doi: 10.1371/journal.pone.0017390.


Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in Native Americans and whites in the Hemochromatosis and Iron Overload Screening Study.

Barton JC, Acton RT, Lovato L, Speechley MR, McLaren CE, Harris EL, Reboussin DM, Adams PC, Dawkins FW, Gordeuk VR, Walker AP; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Clin Genet. 2006 Jan;69(1):48-57.


Common Variants and Haplotypes in the TF, TNF-α, and TMPRSS6 Genes Are Associated with Iron Status in a Female Black South African Population.

Gichohi-Wainaina WN, Melse-Boonstra A, Swinkels DW, Zimmermann MB, Feskens EJ, Towers GW.

J Nutr. 2015 May;145(5):945-53. doi: 10.3945/jn.114.209148. Epub 2015 Mar 25.


Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 hemochromatosis and iron overload screening (HEIRS) study participants.

Acton RT, Barton JC, Leiendecker-Foster C, Zaun C, McLaren CE, Eckfeldt JH.

Blood Cells Mol Dis. 2010 Apr 15;44(4):252-6. doi: 10.1016/j.bcmd.2010.01.007. Epub 2010 Feb 23.


A genome-wide linkage scan for iron phenotype quantitative trait loci: the HEIRS Family Study.

Acton RT, Snively BM, Barton JC, McLaren CE, Adams PC, Rich SS, Eckfeldt JH, Press RD, Sholinsky P, Leiendecker-Foster C, McLaren GD, Speechley MR, Harris EL, Dawkins FW, Gordeuk VR; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Clin Genet. 2007 Jun;71(6):518-29.


Bivariate mixture modeling of transferrin saturation and serum ferritin concentration in Asians, African Americans, Hispanics, and whites in the Hemochromatosis and Iron Overload Screening (HEIRS) Study.

McLaren CE, Gordeuk VR, Chen WP, Barton JC, Acton RT, Speechley M, Castro O, Adams PC, Snively BM, Harris EL, Reboussin DM, McLachlan GJ, Bean R; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Transl Res. 2008 Feb;151(2):97-109. doi: 10.1016/j.trsl.2007.10.002. Epub 2007 Nov 9.


Heme carrier protein 1 (HCP1) genetic variants in the Hemochromatosis and Iron Overload Screening (HEIRS) Study participants.

Wang X, Leiendecker-Foster C, Acton RT, Barton JC, McLaren CE, McLaren GD, Gordeuk VR, Eckfeldt JH.

Blood Cells Mol Dis. 2009 Mar-Apr;42(2):150-4. doi: 10.1016/j.bcmd.2008.11.003. Epub 2009 Jan 26.


Analysis of FTO gene variants with obesity and glucose homeostasis measures in the multiethnic Insulin Resistance Atherosclerosis Study cohort.

Wing MR, Ziegler JM, Langefeld CD, Roh BH, Palmer ND, Mayer-Davis EJ, Rewers MJ, Haffner SM, Wagenknecht LE, Bowden DW.

Int J Obes (Lond). 2011 Sep;35(9):1173-82. doi: 10.1038/ijo.2010.244. Epub 2010 Nov 23.


Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population.

Gan W, Guan Y, Wu Q, An P, Zhu J, Lu L, Jing L, Yu Y, Ruan S, Xie D, Makrides M, Gibson RA, Anderson GJ, Li H, Lin X, Wang F.

Am J Clin Nutr. 2012 Mar;95(3):626-32. doi: 10.3945/ajcn.111.025684. Epub 2012 Feb 1.


Association of interleukin-1 gene variations with moderate to severe chronic periodontitis in multiple ethnicities.

Wu X, Offenbacher S, Lόpez NJ, Chen D, Wang HY, Rogus J, Zhou J, Beck J, Jiang S, Bao X, Wilkins L, Doucette-Stamm L, Kornman K.

J Periodontal Res. 2015 Feb;50(1):52-61. doi: 10.1111/jre.12181. Epub 2014 Apr 2.


Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?

Raffield LM, Louie T, Sofer T, Jain D, Ipp E, Taylor KD, Papanicolaou GJ, Avilés-Santa L, Lange LA, Laurie CC, Conomos MP, Thornton TA, Chen YI, Qi Q, Cotler S, Thyagarajan B, Schneiderman N, Rotter JI, Reiner AP, Lin HJ.

Hum Mol Genet. 2017 May 15;26(10):1966-1978. doi: 10.1093/hmg/ddx082.


Determinants and characteristics of mean corpuscular volume and hemoglobin concentration in white HFE C282Y homozygotes in the hemochromatosis and iron overload screening study.

McLaren CE, Barton JC, Gordeuk VR, Wu L, Adams PC, Reboussin DM, Speechley M, Chang H, Acton RT, Harris EL, Ruggiero AM, Castro O; Hemochromatosis and Iron Overload Screening Study Research Investigators.

Am J Hematol. 2007 Oct;82(10):898-905.


Haplotype-based association studies of IGFBP1 and IGFBP3 with prostate and breast cancer risk: the multiethnic cohort.

Cheng I, Penney KL, Stram DO, Le Marchand L, Giorgi E, Haiman CA, Kolonel LN, Pike M, Hirschhorn J, Henderson BE, Freedman ML.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1993-7.


Relationships of serum ferritin, transferrin saturation, and HFE mutations and self-reported diabetes in the Hemochromatosis and Iron Overload Screening (HEIRS) study.

Acton RT, Barton JC, Passmore LV, Adams PC, Speechley MR, Dawkins FW, Sholinsky P, Reboussin DM, McLaren GD, Harris EL, Bent TC, Vogt TM, Castro O.

Diabetes Care. 2006 Sep;29(9):2084-9.


Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study.

McLaren GD, Gordeuk VR.

Hematology Am Soc Hematol Educ Program. 2009:195-206. doi: 10.1182/asheducation-2009.1.195.


Genome-wide admixture and association study of serum iron, ferritin, transferrin saturation and total iron binding capacity in African Americans.

Li J, Lange LA, Duan Q, Lu Y, Singleton AB, Zonderman AB, Evans MK, Li Y, Taylor HA, Willis MS, Nalls M, Wilson JG, Lange EM.

Hum Mol Genet. 2015 Jan 15;24(2):572-81. doi: 10.1093/hmg/ddu454. Epub 2014 Sep 15.


Replication and heritability of prostate cancer risk variants: impact of population-specific factors.

Virlogeux V, Graff RE, Hoffmann TJ, Witte JS.

Cancer Epidemiol Biomarkers Prev. 2015 Jun;24(6):938-43. doi: 10.1158/1055-9965.EPI-14-1372. Epub 2015 Mar 25.


HFE C282Y homozygotes aged 25-29 years at HEIRS Study initial screening.

Barton JC, Acton RT, Leiendecker-Foster C, Lovato L, Adams PC, McLaren GD, Eckfeldt JH, McLaren CE, Reboussin DM, Gordeuk VR, Speechley MR, Reiss JA, Press RD, Dawkins FW; Hemochromatosis and Iron Overload Screening (HEIRS) Study Research Investigators.

Genet Test. 2007 Fall;11(3):269-75.


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