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Regulation of organic cation transport in isolated mouse proximal tubules involves complex changes in protein trafficking and substrate affinity.

Guckel D, Ciarimboli G, Pavenstädt H, Schlatter E.

Cell Physiol Biochem. 2012;30(1):269-81. doi: 10.1159/000339063. Epub 2012 Jun 19.


Properties and regulation of organic cation transport in freshly isolated mouse proximal tubules analyzed with a fluorescence reader-based method.

Holle SK, Ciarimboli G, Edemir B, Neugebauer U, Pavenstädt H, Schlatter E.

Pflugers Arch. 2011 Aug;462(2):359-69. doi: 10.1007/s00424-011-0969-7. Epub 2011 Apr 27.


Properties and regulation of organic cation transport in freshly isolated human proximal tubules.

Pietig G, Mehrens T, Hirsch JR, Cetinkaya I, Piechota H, Schlatter E.

J Biol Chem. 2001 Sep 7;276(36):33741-6. Epub 2001 Jul 10.


Characterization of regulatory mechanisms and states of human organic cation transporter 2.

Biermann J, Lang D, Gorboulev V, Koepsell H, Sindic A, Schröter R, Zvirbliene A, Pavenstädt H, Schlatter E, Ciarimboli G.

Am J Physiol Cell Physiol. 2006 Jun;290(6):C1521-31. Epub 2006 Jan 4.


Regulation of human organic cation transporter hOCT2 by PKA, PI3K, and calmodulin-dependent kinases.

Cetinkaya I, Ciarimboli G, Yalçinkaya G, Mehrens T, Velic A, Hirsch JR, Gorboulev V, Koepsell H, Schlatter E.

Am J Physiol Renal Physiol. 2003 Feb;284(2):F293-302. Epub 2002 Oct 15.


Regulation of organic cation transport in IHKE-1 and LLC-PK1 cells. Fluorometric studies with 4-(4-dimethylaminostyryl)-N-methylpyridinium.

Hohage H, Stachon A, Feidt C, Hirsch JR, Schlatter E.

J Pharmacol Exp Ther. 1998 Jul;286(1):305-10.


Calmodulin-associated post-translational regulation of rat organic cation transporter 2 in the kidney is gender dependent.

Wilde S, Schlatter E, Koepsell H, Edemir B, Reuter S, Pavenstädt H, Neugebauer U, Schröter R, Brast S, Ciarimboli G.

Cell Mol Life Sci. 2009 May;66(10):1729-40. doi: 10.1007/s00018-009-9145-z.


The affinity of the organic cation transporter rOCT1 is increased by protein kinase C-dependent phosphorylation.

Mehrens T, Lelleck S, Cetinkaya I, Knollmann M, Hohage H, Gorboulev V, Bokník P, Koepsell H, Schlatter E.

J Am Soc Nephrol. 2000 Jul;11(7):1216-24.


Evidence for differential regulation of renal proximal tubular p-aminohippurate and sodium-dependent dicarboxylate transport.

Gabriëls G, Werners A, Mauss S, Greven J.

J Pharmacol Exp Ther. 1999 Aug;290(2):710-5.


Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+.

Thévenod F, Ciarimboli G, Leistner M, Wolff NA, Lee WK, Schatz I, Keller T, Al-Monajjed R, Gorboulev V, Koepsell H.

Mol Pharm. 2013 Aug 5;10(8):3045-56. doi: 10.1021/mp400113d. Epub 2013 Jun 24.


The organic cation transporter 3 (OCT3) as molecular target of psychotropic drugs: transport characteristics and acute regulation of cloned murine OCT3.

Massmann V, Edemir B, Schlatter E, Al-Monajjed R, Harrach S, Klassen P, Holle SK, Sindic A, Dobrivojevic M, Pavenstädt H, Ciarimboli G.

Pflugers Arch. 2014 Mar;466(3):517-27. doi: 10.1007/s00424-013-1335-8. Epub 2013 Aug 28.


Mouse organic cation transporter 1 determines properties and regulation of basolateral organic cation transport in renal proximal tubules.

Schlatter E, Klassen P, Massmann V, Holle SK, Guckel D, Edemir B, Pavenstädt H, Ciarimboli G.

Pflugers Arch. 2014 Aug;466(8):1581-9.


Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy.

Hörbelt M, Wotzlaw C, Sutton TA, Molitoris BA, Philipp T, Kribben A, Fandrey J, Pietruck F.

Kidney Int. 2007 Aug;72(4):422-9. Epub 2007 May 2.


Regulation of the human organic cation transporter hOCT1.

Ciarimboli G, Struwe K, Arndt P, Gorboulev V, Koepsell H, Schlatter E, Hirsch JR.

J Cell Physiol. 2004 Dec;201(3):420-8.


Digital fluorescence imaging of organic cation transport in freshly isolated rat proximal tubules.

Pietruck F, Horbelt M, Feldkamp T, Engeln K, Herget-Rosenthal S, Philipp T, Kribben A.

Drug Metab Dispos. 2006 Mar;34(3):339-42. Epub 2005 Dec 8.


Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules.

Soodvilai S, Chatsudthipong V, Evans KK, Wright SH, Dantzler WH.

Am J Physiol Renal Physiol. 2004 Nov;287(5):F1021-9. Epub 2004 Jul 6.


The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.

Schlatter E, Mönnich V, Cetinkaya I, Mehrens T, Ciarimboli G, Hirsch JR, Popp C, Koepsell H.

J Membr Biol. 2002 Oct 1;189(3):237-44.


Organic cation transporters OCT1, 2, and 3 mediate high-affinity transport of the mutagenic vital dye ethidium in the kidney proximal tubule.

Lee WK, Reichold M, Edemir B, Ciarimboli G, Warth R, Koepsell H, Thévenod F.

Am J Physiol Renal Physiol. 2009 Jun;296(6):F1504-13. doi: 10.1152/ajprenal.90754.2008. Epub 2009 Apr 8.


Transport of the fluorescent organic cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells.

Salomon JJ, Endter S, Tachon G, Falson F, Buckley ST, Ehrhardt C.

Eur J Pharm Biopharm. 2012 Jun;81(2):351-9. doi: 10.1016/j.ejpb.2012.03.001. Epub 2012 Mar 8.


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