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Items: 1 to 20 of 190

1.

D2-like dopamine and β-adrenergic receptors form a signaling complex that integrates Gs- and Gi-mediated regulation of adenylyl cyclase.

Rebois RV, Maki K, Meeks JA, Fishman PH, Hébert TE, Northup JK.

Cell Signal. 2012 Nov;24(11):2051-60. doi: 10.1016/j.cellsig.2012.06.011. Epub 2012 Jul 1.

2.

Assembly and function of the regulator of G protein signaling 14 (RGS14)·H-Ras signaling complex in live cells are regulated by Gαi1 and Gαi-linked G protein-coupled receptors.

Vellano CP, Brown NE, Blumer JB, Hepler JR.

J Biol Chem. 2013 Feb 1;288(5):3620-31. doi: 10.1074/jbc.M112.440057. Epub 2012 Dec 17.

3.

RGS2 interacts with Gs and adenylyl cyclase in living cells.

Roy AA, Baragli A, Bernstein LS, Hepler JR, Hébert TE, Chidiac P.

Cell Signal. 2006 Mar;18(3):336-48. Epub 2005 Aug 10.

PMID:
16095880
4.

Stable association of G proteins with beta 2AR is independent of the state of receptor activation.

Lachance M, Ethier N, Wolbring G, Schnetkamp PP, Hébert TE.

Cell Signal. 1999 Jul;11(7):523-33.

PMID:
10405763
5.

Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system.

Zamah AM, Delahunty M, Luttrell LM, Lefkowitz RJ.

J Biol Chem. 2002 Aug 23;277(34):31249-56. Epub 2002 Jun 12.

6.

Beta(2)-adrenergic and several other G protein-coupled receptors in human atrial membranes activate both G(s) and G(i).

Kilts JD, Gerhardt MA, Richardson MD, Sreeram G, Mackensen GB, Grocott HP, White WD, Davis RD, Newman MF, Reves JG, Schwinn DA, Kwatra MM.

Circ Res. 2000 Oct 13;87(8):705-9.

7.

N terminus of type 5 adenylyl cyclase scaffolds Gs heterotrimer.

Sadana R, Dascal N, Dessauer CW.

Mol Pharmacol. 2009 Dec;76(6):1256-64. doi: 10.1124/mol.109.058370. Epub 2009 Sep 25.

8.

Molecular analysis of beta(2)-adrenoceptor coupling to G(s)-, G(i)-, and G(q)-proteins.

Wenzel-Seifert K, Seifert R.

Mol Pharmacol. 2000 Nov;58(5):954-66.

9.

RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling.

Chakir K, Zhu W, Tsang S, Woo AY, Yang D, Wang X, Zeng X, Rhee MH, Mende U, Koitabashi N, Takimoto E, Blumer KJ, Lakatta EG, Kass DA, Xiao RP.

J Mol Cell Cardiol. 2011 Jun;50(6):1000-7. doi: 10.1016/j.yjmcc.2011.01.015. Epub 2011 Feb 1.

10.

Multiple signaling routes involved in the regulation of adenylyl cyclase and extracellular regulated kinase by dopamine D(2) and D(3) receptors.

Jin M, Min C, Zheng M, Cho DI, Cheong SJ, Kurose H, Kim KM.

Pharmacol Res. 2013 Jan;67(1):31-41. doi: 10.1016/j.phrs.2012.09.012. Epub 2012 Oct 8.

PMID:
23059541
11.
12.
13.

Paradoxical attenuation of β2-AR function in airway smooth muscle by Gi-mediated counterregulation in transgenic mice overexpressing type 5 adenylyl cyclase.

Wang WC, Schillinger RM, Malone MM, Liggett SB.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L472-8. doi: 10.1152/ajplung.00273.2010. Epub 2010 Dec 3.

14.

Rabbit erythrocytes possess adenylyl cyclase type II that is activated by the heterotrimeric G proteins Gs and Gi.

Sprague R, Bowles E, Stumpf M, Ricketts G, Freidman A, Hou WH, Stephenson A, Lonigro A.

Pharmacol Rep. 2005;57 Suppl:222-8.

15.

Contribution of the extracellular cAMP-adenosine pathway to dual coupling of β2-adrenoceptors to Gs and Gi proteins in mouse skeletal muscle.

Duarte T, Menezes-Rodrigues FS, Godinho RO.

J Pharmacol Exp Ther. 2012 Jun;341(3):820-8. doi: 10.1124/jpet.112.192997. Epub 2012 Mar 21.

16.

Receptor-mediated adenylyl cyclase activation through XLalpha(s), the extra-large variant of the stimulatory G protein alpha-subunit.

Bastepe M, Gunes Y, Perez-Villamil B, Hunzelman J, Weinstein LS, Jüppner H.

Mol Endocrinol. 2002 Aug;16(8):1912-9.

PMID:
12145344
18.
19.

Competition for Gβγ dimers mediates a specific cross-talk between stimulatory and inhibitory G protein α subunits of the adenylyl cyclase in cardiomyocytes.

Hippe HJ, Lüdde M, Schnoes K, Novakovic A, Lutz S, Katus HA, Niroomand F, Nürnberg B, Frey N, Wieland T.

Naunyn Schmiedebergs Arch Pharmacol. 2013 Jun;386(6):459-69. doi: 10.1007/s00210-013-0876-x. Epub 2013 Apr 26.

PMID:
23615874
20.

Age increases cardiac Galpha(i2) expression, resulting in enhanced coupling to G protein-coupled receptors.

Kilts JD, Akazawa T, Richardson MD, Kwatra MM.

J Biol Chem. 2002 Aug 23;277(34):31257-62. Epub 2002 Jun 13.

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