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Chronic free-choice drinking in crossed high alcohol preferring mice leads to sustained blood ethanol levels and metabolic tolerance without evidence of liver damage.

Matson L, Liangpunsakul S, Crabb D, Buckingham A, Ross RA, Halcomb M, Grahame N.

Alcohol Clin Exp Res. 2013 Feb;37(2):194-201. doi: 10.1111/j.1530-0277.2012.01873.x. Epub 2012 Jul 3.


Selectively bred crossed high-alcohol-preferring mice drink to intoxication and develop functional tolerance, but not locomotor sensitization during free-choice ethanol access.

Matson LM, Kasten CR, Boehm SL 2nd, Grahame NJ.

Alcohol Clin Exp Res. 2014 Jan;38(1):267-74. doi: 10.1111/acer.12216. Epub 2013 Aug 1.


Pharmacologically relevant intake during chronic, free-choice drinking rhythms in selectively bred high alcohol-preferring mice.

Matson LM, Grahame NJ.

Addict Biol. 2013 Nov;18(6):921-9. doi: 10.1111/j.1369-1600.2011.00412.x. Epub 2011 Nov 29.


Genetic relationship between predisposition for binge alcohol consumption and blunted sensitivity to adverse effects of alcohol in mice.

Fritz BM, Cordero KA, Barkley-Levenson AM, Metten P, Crabbe JC, Boehm SL 2nd.

Alcohol Clin Exp Res. 2014 May;38(5):1284-92. doi: 10.1111/acer.12385. Epub 2014 Feb 25.


CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis.

Abdelmegeed MA, Banerjee A, Jang S, Yoo SH, Yun JW, Gonzalez FJ, Keshavarzian A, Song BJ.

Free Radic Biol Med. 2013 Dec;65:1238-45. doi: 10.1016/j.freeradbiomed.2013.09.009. Epub 2013 Sep 21.


Pregnane X Receptor-Humanized Mice Recapitulate Gender Differences in Ethanol Metabolism but Not Hepatotoxicity.

Spruiell K, Gyamfi AA, Yeyeodu ST, Richardson RM, Gonzalez FJ, Gyamfi MA.

J Pharmacol Exp Ther. 2015 Sep;354(3):459-70. doi: 10.1124/jpet.115.224295. Epub 2015 Jul 9.


Ethanol drinking microstructure of a high drinking in the dark selected mouse line.

Barkley-Levenson AM, Crabbe JC.

Alcohol Clin Exp Res. 2012 Aug;36(8):1330-9. doi: 10.1111/j.1530-0277.2012.01749.x. Epub 2012 Apr 23.


Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats.

Roberts BJ, Shoaf SE, Song BJ.

Biochem Pharmacol. 1995 May 26;49(11):1665-73.


Chronic voluntary alcohol consumption results in tolerance to sedative/hypnotic and hypothermic effects of alcohol in hybrid mice.

Ozburn AR, Harris RA, Blednov YA.

Pharmacol Biochem Behav. 2013 Mar;104:33-9. doi: 10.1016/j.pbb.2012.12.025. Epub 2013 Jan 8.


Ethanol tolerance and withdrawal severity in high drinking in the dark selectively bred mice.

Crabbe JC, Colville AM, Kruse LC, Cameron AJ, Spence SE, Schlumbohm JP, Huang LC, Metten P.

Alcohol Clin Exp Res. 2012 Jul;36(7):1152-61. doi: 10.1111/j.1530-0277.2011.01715.x. Epub 2012 Feb 6.


A procedure to produce high alcohol intake in mice.

Finn DA, Belknap JK, Cronise K, Yoneyama N, Murillo A, Crabbe JC.

Psychopharmacology (Berl). 2005 Apr;178(4):471-80. Epub 2004 Nov 3.


Physiologic and genomic analyses of nutrition-ethanol interactions during gestation: Implications for fetal ethanol toxicity.

Shankar K, Hidestrand M, Liu X, Xiao R, Skinner CM, Simmen FA, Badger TM, Ronis MJ.

Exp Biol Med (Maywood). 2006 Sep;231(8):1379-97.


Effects of intoxicating free-choice alcohol consumption during adolescence on drinking and impulsivity during adulthood in selectively bred high-alcohol preferring mice.

O'Tousa DS, Matson LM, Grahame NJ.

Alcohol Clin Exp Res. 2013 Jan;37(1):141-9. doi: 10.1111/j.1530-0277.2012.01857.x. Epub 2012 Jun 22.


Assessment of the Effects of 6 Standard Rodent Diets on Binge-Like and Voluntary Ethanol Consumption in Male C57BL/6J Mice.

Marshall SA, Rinker JA, Harrison LK, Fletcher CA, Herfel TM, Thiele TE.

Alcohol Clin Exp Res. 2015 Aug;39(8):1406-16. doi: 10.1111/acer.12773. Epub 2015 Jun 25.


Similar ethanol drinking in adolescent and adult C57BL/6J mice after chronic ethanol exposure and withdrawal.

Carrara-Nascimento PF, Lopez MF, Becker HC, Olive MF, Camarini R.

Alcohol Clin Exp Res. 2013 Jun;37(6):961-8. doi: 10.1111/acer.12056. Epub 2013 Jan 8.


The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake.

Quintanilla ME, Israel Y, Sapag A, Tampier L.

Addict Biol. 2006 Sep;11(3-4):310-23. Review.


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