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Items: 1 to 20 of 116

1.

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development.

Morita M, Ler LW, Fabian MR, Siddiqui N, Mullin M, Henderson VC, Alain T, Fonseca BD, Karashchuk G, Bennett CF, Kabuta T, Higashi S, Larsson O, Topisirovic I, Smith RJ, Gingras AC, Sonenberg N.

Mol Cell Biol. 2012 Sep;32(17):3585-93. doi: 10.1128/MCB.00455-12. Epub 2012 Jul 2.

2.

Patterning of the Drosophila oocyte by a sequential translation repression program involving the d4EHP and Belle translational repressors.

Yarunin A, Harris RE, Ashe MP, Ashe HL.

RNA Biol. 2011 Sep-Oct;8(5):904-12. doi: 10.4161/rna.8.5.16325. Epub 2011 Jul 26.

PMID:
21788736
3.

A new paradigm for translational control: inhibition via 5'-3' mRNA tethering by Bicoid and the eIF4E cognate 4EHP.

Cho PF, Poulin F, Cho-Park YA, Cho-Park IB, Chicoine JD, Lasko P, Sonenberg N.

Cell. 2005 May 6;121(3):411-23.

4.

Characterizing the interaction of the mammalian eIF4E-related protein 4EHP with 4E-BP1.

Tee AR, Tee JA, Blenis J.

FEBS Lett. 2004 Apr 23;564(1-2):58-62.

5.

Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP.

Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA.

FEBS Lett. 2003 Nov 20;554(3):501-4.

6.

Structures of the human eIF4E homologous protein, h4EHP, in its m7GTP-bound and unliganded forms.

Rosettani P, Knapp S, Vismara MG, Rusconi L, Cameron AD.

J Mol Biol. 2007 May 4;368(3):691-705. Epub 2007 Feb 20.

PMID:
17368478
7.

High affinity RNA for mammalian initiation factor 4E interferes with mRNA-cap binding and inhibits translation.

Mochizuki K, Oguro A, Ohtsu T, Sonenberg N, Nakamura Y.

RNA. 2005 Jan;11(1):77-89.

8.

GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression.

Peter D, Weber R, Sandmeir F, Wohlbold L, Helms S, Bawankar P, Valkov E, Igreja C, Izaurralde E.

Genes Dev. 2017 Jun 1;31(11):1147-1161. doi: 10.1101/gad.299420.117. Epub 2017 Jul 11.

9.

The 4E-BP Caf20p Mediates Both eIF4E-Dependent and Independent Repression of Translation.

Castelli LM, Talavera D, Kershaw CJ, Mohammad-Qureshi SS, Costello JL, Rowe W, Sims PF, Grant CM, Hubbard SJ, Ashe MP, Pavitt GD.

PLoS Genet. 2015 May 14;11(5):e1005233. doi: 10.1371/journal.pgen.1005233. eCollection 2015 May.

10.

Contrasting mechanisms of regulating translation of specific Drosophila germline mRNAs at the level of 5'-cap structure binding.

Lasko P, Cho P, Poulin F, Sonenberg N.

Biochem Soc Trans. 2005 Dec;33(Pt 6):1544-6. Review.

PMID:
16246166
11.

Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements.

Fu R, Olsen MT, Webb K, Bennett EJ, Lykke-Andersen J.

RNA. 2016 Mar;22(3):373-82. doi: 10.1261/rna.054833.115. Epub 2016 Jan 13.

12.

Characterization of mammalian eIF4E-family members.

Joshi B, Cameron A, Jagus R.

Eur J Biochem. 2004 Jun;271(11):2189-203.

13.

The DDX6-4E-T interaction mediates translational repression and P-body assembly.

Kamenska A, Simpson C, Vindry C, Broomhead H, Bénard M, Ernoult-Lange M, Lee BP, Harries LW, Weil D, Standart N.

Nucleic Acids Res. 2016 Jul 27;44(13):6318-34. doi: 10.1093/nar/gkw565. Epub 2016 Jun 24.

14.

Translational homeostasis via the mRNA cap-binding protein, eIF4E.

Yanagiya A, Suyama E, Adachi H, Svitkin YV, Aza-Blanc P, Imataka H, Mikami S, Martineau Y, Ronai ZA, Sonenberg N.

Mol Cell. 2012 Jun 29;46(6):847-58. doi: 10.1016/j.molcel.2012.04.004. Epub 2012 May 10.

15.

Cytoplasmic Prep1 interacts with 4EHP inhibiting Hoxb4 translation.

Villaescusa JC, Buratti C, Penkov D, Mathiasen L, Planagumà J, Ferretti E, Blasi F.

PLoS One. 2009;4(4):e5213. doi: 10.1371/journal.pone.0005213. Epub 2009 Apr 13.

16.

L-serine deficiency caused by genetic Phgdh deletion leads to robust induction of 4E-BP1 and subsequent repression of translation initiation in the developing central nervous system.

Sayano T, Kawakami Y, Kusada W, Suzuki T, Kawano Y, Watanabe A, Takashima K, Arimoto Y, Esaki K, Wada A, Yoshizawa F, Watanabe M, Okamoto M, Hirabayashi Y, Furuya S.

FEBS J. 2013 Mar;280(6):1502-17. doi: 10.1111/febs.12146. Epub 2013 Feb 24.

18.

The nematode eukaryotic translation initiation factor 4E/G complex works with a trans-spliced leader stem-loop to enable efficient translation of trimethylguanosine-capped RNAs.

Wallace A, Filbin ME, Veo B, McFarland C, Stepinski J, Jankowska-Anyszka M, Darzynkiewicz E, Davis RE.

Mol Cell Biol. 2010 Apr;30(8):1958-70. doi: 10.1128/MCB.01437-09. Epub 2010 Feb 12.

19.

Crystal structure of a minimal eIF4E-Cup complex reveals a general mechanism of eIF4E regulation in translational repression.

Kinkelin K, Veith K, Grünwald M, Bono F.

RNA. 2012 Sep;18(9):1624-34. doi: 10.1261/rna.033639.112. Epub 2012 Jul 25.

20.

Mextli is a novel eukaryotic translation initiation factor 4E-binding protein that promotes translation in Drosophila melanogaster.

Hernández G, Miron M, Han H, Liu N, Magescas J, Tettweiler G, Frank F, Siddiqui N, Sonenberg N, Lasko P.

Mol Cell Biol. 2013 Aug;33(15):2854-64. doi: 10.1128/MCB.01354-12. Epub 2013 May 28.

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