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Items: 1 to 20 of 92


Unraveling cell type-specific and reprogrammable human replication origin signatures associated with G-quadruplex consensus motifs.

Besnard E, Babled A, Lapasset L, Milhavet O, Parrinello H, Dantec C, Marin JM, Lemaitre JM.

Nat Struct Mol Biol. 2012 Aug;19(8):837-44. doi: 10.1038/nsmb.2339. Epub 2012 Jul 1.


G4 motifs affect origin positioning and efficiency in two vertebrate replicators.

Valton AL, Hassan-Zadeh V, Lema I, Boggetto N, Alberti P, Saintomé C, Riou JF, Prioleau MN.

EMBO J. 2014 Apr 1;33(7):732-46. doi: 10.1002/embj.201387506. Epub 2014 Feb 12.


Genome-wide identification and characterisation of human DNA replication origins by initiation site sequencing (ini-seq).

Langley AR, Gräf S, Smith JC, Krude T.

Nucleic Acids Res. 2016 Dec 1;44(21):10230-10247. Epub 2016 Sep 1.


Broader utilization of origins of DNA replication in cancer cell lines along a 78 kb region of human chromosome 2q34.

Valenzuela MS, Hu L, Lueders J, Walker R, Meltzer PS.

J Cell Biochem. 2012 Jan;113(1):132-40. doi: 10.1002/jcb.23336.


New insights into replication origin characteristics in metazoans.

Cayrou C, Coulombe P, Puy A, Rialle S, Kaplan N, Segal E, Méchali M.

Cell Cycle. 2012 Feb 15;11(4):658-67. doi: 10.4161/cc.11.4.19097.


Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences.

Valenzuela MS, Chen Y, Davis S, Yang F, Walker RL, Bilke S, Lueders J, Martin MM, Aladjem MI, Massion PP, Meltzer PS.

PLoS One. 2011;6(5):e17308. doi: 10.1371/journal.pone.0017308. Epub 2011 May 13.


G-Quadruplexes in DNA Replication: A Problem or a Necessity?

Valton AL, Prioleau MN.

Trends Genet. 2016 Nov;32(11):697-706. doi: 10.1016/j.tig.2016.09.004. Epub 2016 Sep 20. Review.


High-resolution profiling of Drosophila replication start sites reveals a DNA shape and chromatin signature of metazoan origins.

Comoglio F, Schlumpf T, Schmid V, Rohs R, Beisel C, Paro R.

Cell Rep. 2015 May 5;11(5):821-34. doi: 10.1016/j.celrep.2015.03.070. Epub 2015 Apr 23.


The chromatin environment shapes DNA replication origin organization and defines origin classes.

Cayrou C, Ballester B, Peiffer I, Fenouil R, Coulombe P, Andrau JC, van Helden J, Méchali M.

Genome Res. 2015 Dec;25(12):1873-85. doi: 10.1101/gr.192799.115. Epub 2015 Nov 11.


Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features.

Cayrou C, Coulombe P, Vigneron A, Stanojcic S, Ganier O, Peiffer I, Rivals E, Puy A, Laurent-Chabalier S, Desprat R, Méchali M.

Genome Res. 2011 Sep;21(9):1438-49. doi: 10.1101/gr.121830.111. Epub 2011 Jul 12.


QGRS-Conserve: a computational method for discovering evolutionarily conserved G-quadruplex motifs.

Frees S, Menendez C, Crum M, Bagga PS.

Hum Genomics. 2014 May 1;8:8. doi: 10.1186/1479-7364-8-8.


Genome-wide identification and characterization of replication origins by deep sequencing.

Xu J, Yanagisawa Y, Tsankov AM, Hart C, Aoki K, Kommajosyula N, Steinmann KE, Bochicchio J, Russ C, Regev A, Rando OJ, Nusbaum C, Niki H, Milos P, Weng Z, Rhind N.

Genome Biol. 2012 Apr 24;13(4):R27. doi: 10.1186/gb-2012-13-4-r27.


Allele-specific analysis of DNA replication origins in mammalian cells.

Bartholdy B, Mukhopadhyay R, Lajugie J, Aladjem MI, Bouhassira EE.

Nat Commun. 2015 May 19;6:7051. doi: 10.1038/ncomms8051.


High-throughput mapping of origins of replication in human cells.

Lucas I, Palakodeti A, Jiang Y, Young DJ, Jiang N, Fernald AA, Le Beau MM.

EMBO Rep. 2007 Aug;8(8):770-7. Epub 2007 Jul 13.


Genetic and epigenetic determinants of DNA replication origins, position and activation.

Méchali M, Yoshida K, Coulombe P, Pasero P.

Curr Opin Genet Dev. 2013 Apr;23(2):124-31. doi: 10.1016/j.gde.2013.02.010. Epub 2013 Mar 28. Review.


Same origins of DNA replication function on the active and inactive human X chromosomes.

Cohen SM, Brylawski BP, Cordeiro-Stone M, Kaufman DG.

J Cell Biochem. 2003 Apr 1;88(5):923-31.


DNA replication origins-where do we begin?

Prioleau MN, MacAlpine DM.

Genes Dev. 2016 Aug 1;30(15):1683-97. doi: 10.1101/gad.285114.116. Review.


Identification of new human origins of DNA replication by an origin-trapping assay.

Gerhardt J, Jafar S, Spindler MP, Ott E, Schepers A.

Mol Cell Biol. 2006 Oct;26(20):7731-46. Epub 2006 Sep 5. Erratum in: Mol Cell Biol. 2007 Jan;27(2):788.


Functional genomic mapping of an early-activated centromeric mammalian origin of DNA replication.

Pelletier R, Price GB, Zannis-Hadjopoulos M.

J Cell Biochem. 1999 Sep 15;74(4):562-75.


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