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Items: 1 to 20 of 107

1.

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation.

van Horssen J, Singh S, van der Pol S, Kipp M, Lim JL, Peferoen L, Gerritsen W, Kooi EJ, Witte ME, Geurts JJ, de Vries HE, Peferoen-Baert R, van den Elsen PJ, van der Valk P, Amor S.

J Neuroinflammation. 2012 Jul 2;9:156. doi: 10.1186/1742-2094-9-156.

2.

Upregulation of transcription factors controlling MHC expression in multiple sclerosis lesions.

Gobin SJ, Montagne L, Van Zutphen M, Van Der Valk P, Van Den Elsen PJ, De Groot CJ.

Glia. 2001 Oct;36(1):68-77.

PMID:
11571785
3.

Alpha-B-crystallin induces an immune-regulatory and antiviral microglial response in preactive multiple sclerosis lesions.

Bsibsi M, Holtman IR, Gerritsen WH, Eggen BJ, Boddeke E, van der Valk P, van Noort JM, Amor S.

J Neuropathol Exp Neurol. 2013 Oct;72(10):970-9. doi: 10.1097/NEN.0b013e3182a776bf.

PMID:
24042199
4.

Preactive multiple sclerosis lesions offer novel clues for neuroprotective therapeutic strategies.

van Noort JM, van den Elsen PJ, van Horssen J, Geurts JJ, van der Valk P, Amor S.

CNS Neurol Disord Drug Targets. 2011 Feb;10(1):68-81. Review.

PMID:
21143143
5.

Preactive lesions in multiple sclerosis.

van der Valk P, Amor S.

Curr Opin Neurol. 2009 Jun;22(3):207-13. doi: 10.1097/WCO.0b013e32832b4c76. Review.

PMID:
19417567
6.

Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons.

Singh S, Metz I, Amor S, van der Valk P, Stadelmann C, Brück W.

Acta Neuropathol. 2013 Apr;125(4):595-608. doi: 10.1007/s00401-013-1082-0. Epub 2013 Jan 26.

7.

Alphab-crystallin is a target for adaptive immune responses and a trigger of innate responses in preactive multiple sclerosis lesions.

van Noort JM, Bsibsi M, Gerritsen WH, van der Valk P, Bajramovic JJ, Steinman L, Amor S.

J Neuropathol Exp Neurol. 2010 Jul;69(7):694-703. doi: 10.1097/NEN.0b013e3181e4939c.

PMID:
20535035
8.
9.

Pathological abnormalities in the normal-appearing white matter in multiple sclerosis.

Allen IV, McQuaid S, Mirakhur M, Nevin G.

Neurol Sci. 2001 Apr;22(2):141-4. Review.

PMID:
11603615
10.

Increased expression of distinct galectins in multiple sclerosis lesions.

Stancic M, van Horssen J, Thijssen VL, Gabius HJ, van der Valk P, Hoekstra D, Baron W.

Neuropathol Appl Neurobiol. 2011 Oct;37(6):654-71. doi: 10.1111/j.1365-2990.2011.01184.x.

PMID:
21501208
11.

Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed.

Melief J, Schuurman KG, van de Garde MD, Smolders J, van Eijk M, Hamann J, Huitinga I.

Glia. 2013 Nov;61(11):1848-61. doi: 10.1002/glia.22562. Epub 2013 Sep 6.

PMID:
24014207
12.

Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status.

Vogel DY, Vereyken EJ, Glim JE, Heijnen PD, Moeton M, van der Valk P, Amor S, Teunissen CE, van Horssen J, Dijkstra CD.

J Neuroinflammation. 2013 Mar 4;10:35. doi: 10.1186/1742-2094-10-35.

13.

Progranulin expression in brain tissue and cerebrospinal fluid levels in multiple sclerosis.

Vercellino M, Grifoni S, Romagnolo A, Masera S, Mattioda A, Trebini C, Chiavazza C, Caligiana L, Capello E, Mancardi GL, Giobbe D, Mutani R, Giordana MT, Cavalla P.

Mult Scler. 2011 Oct;17(10):1194-201. doi: 10.1177/1352458511406164. Epub 2011 May 25.

14.

Activation status of human microglia is dependent on lesion formation stage and remyelination in multiple sclerosis.

Peferoen LA, Vogel DY, Ummenthum K, Breur M, Heijnen PD, Gerritsen WH, Peferoen-Baert RM, van der Valk P, Dijkstra CD, Amor S.

J Neuropathol Exp Neurol. 2015 Jan;74(1):48-63. doi: 10.1097/NEN.0000000000000149.

PMID:
25470347
15.

Contribution of astrocyte-derived IL-15 to CD8 T cell effector functions in multiple sclerosis.

Saikali P, Antel JP, Pittet CL, Newcombe J, Arbour N.

J Immunol. 2010 Nov 15;185(10):5693-703. doi: 10.4049/jimmunol.1002188. Epub 2010 Oct 6.

16.
17.

BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells?

Stadelmann C, Kerschensteiner M, Misgeld T, Brück W, Hohlfeld R, Lassmann H.

Brain. 2002 Jan;125(Pt 1):75-85.

PMID:
11834594
18.

Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions.

Koning N, Swaab DF, Hoek RM, Huitinga I.

J Neuropathol Exp Neurol. 2009 Feb;68(2):159-67. doi: 10.1097/NEN.0b013e3181964113. Erratum in: J Neuropathol Exp Neurol. 2009 May;68(5):594.

PMID:
19151626
19.

Expression of the immune-tolerogenic major histocompatibility molecule HLA-G in multiple sclerosis: implications for CNS immunity.

Wiendl H, Feger U, Mittelbronn M, Jack C, Schreiner B, Stadelmann C, Antel J, Brueck W, Meyermann R, Bar-Or A, Kieseier BC, Weller M.

Brain. 2005 Nov;128(Pt 11):2689-704. Epub 2005 Aug 25.

PMID:
16123145
20.

Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?

Marik C, Felts PA, Bauer J, Lassmann H, Smith KJ.

Brain. 2007 Nov;130(Pt 11):2800-15.

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