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Items: 1 to 20 of 91

1.

Hfe deficiency impairs pulmonary neutrophil recruitment in response to inflammation.

Benesova K, Vujić Spasić M, Schaefer SM, Stolte J, Baehr-Ivacevic T, Waldow K, Zhou Z, Klingmueller U, Benes V, Mall MA, Muckenthaler MU.

PLoS One. 2012;7(6):e39363. doi: 10.1371/journal.pone.0039363. Epub 2012 Jun 21.

2.

Attenuated inflammatory responses in hemochromatosis reveal a role for iron in the regulation of macrophage cytokine translation.

Wang L, Johnson EE, Shi HN, Walker WA, Wessling-Resnick M, Cherayil BJ.

J Immunol. 2008 Aug 15;181(4):2723-31.

3.

Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2.

Wallace DF, McDonald CJ, Ostini L, Subramaniam VN.

Blood. 2011 Mar 10;117(10):2960-6. doi: 10.1182/blood-2010-08-303859. Epub 2011 Jan 18.

4.

HFE, the MHC and hemochromatosis: paradigm for an extended function for MHC class I.

Cardoso CS, de Sousa M.

Tissue Antigens. 2003 Apr;61(4):263-75. Review.

PMID:
12753664
5.

Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.

Finberg KE, Whittlesey RL, Andrews NC.

Blood. 2011 Apr 28;117(17):4590-9. doi: 10.1182/blood-2010-10-315507. Epub 2011 Feb 25.

6.

Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis.

Ludwiczek S, Theurl I, Bahram S, Schümann K, Weiss G.

J Cell Physiol. 2005 Aug;204(2):489-99.

PMID:
15744772
7.

HFE gene knockout produces mouse model of hereditary hemochromatosis.

Zhou XY, Tomatsu S, Fleming RE, Parkkila S, Waheed A, Jiang J, Fei Y, Brunt EM, Ruddy DA, Prass CE, Schatzman RC, O'Neill R, Britton RS, Bacon BR, Sly WS.

Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2492-7.

8.

Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin.

Kent P, Wilkinson N, Constante M, Fillebeen C, Gkouvatsos K, Wagner J, Buffler M, Becker C, Schümann K, Santos MM, Pantopoulos K.

J Mol Med (Berl). 2015 May;93(5):489-98. doi: 10.1007/s00109-015-1253-7. Epub 2015 Jan 23.

PMID:
25609138
9.

Iron-independent specific protein expression pattern in the liver of HFE-deficient mice.

Petrak J, Myslivcova D, Halada P, Cmejla R, Cmejlova J, Vyoral D, Vulpe CD.

Int J Biochem Cell Biol. 2007;39(5):1006-15. Epub 2007 Jan 28.

PMID:
17376729
10.

Genetic modification of iron metabolism in mice affects the gut microbiota.

Buhnik-Rosenblau K, Moshe-Belizowski S, Danin-Poleg Y, Meyron-Holtz EG.

Biometals. 2012 Oct;25(5):883-92. doi: 10.1007/s10534-012-9555-5. Epub 2012 May 13.

PMID:
22580926
11.

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis.

Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B Jr, Lin HY, Pietrangelo A, Babitt JL.

Gastroenterology. 2009 Oct;137(4):1489-97. doi: 10.1053/j.gastro.2009.06.057. Epub 2009 Jul 7.

12.

Function of the hemochromatosis protein HFE: Lessons from animal models.

Pantopoulos K.

World J Gastroenterol. 2008 Dec 7;14(45):6893-901.

13.

Enhanced erythropoiesis in Hfe-KO mice indicates a role for Hfe in the modulation of erythroid iron homeostasis.

Ramos P, Guy E, Chen N, Proenca CC, Gardenghi S, Casu C, Follenzi A, Van Rooijen N, Grady RW, de Sousa M, Rivella S.

Blood. 2011 Jan 27;117(4):1379-89. doi: 10.1182/blood-2010-09-307462. Epub 2010 Nov 8.

14.

Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis.

Muckenthaler M, Roy CN, Custodio AO, Miñana B, deGraaf J, Montross LK, Andrews NC, Hentze MW.

Nat Genet. 2003 May;34(1):102-7.

PMID:
12704390
15.

HJV and HFE Play Distinct Roles in Regulating Hepcidin.

Wu Q, Wang H, An P, Tao Y, Deng J, Zhang Z, Shen Y, Chen C, Min J, Wang F.

Antioxid Redox Signal. 2015 May 20;22(15):1325-36. doi: 10.1089/ars.2013.5819. Epub 2015 Mar 19.

16.

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice.

Corradini E, Schmidt PJ, Meynard D, Garuti C, Montosi G, Chen S, Vukicevic S, Pietrangelo A, Lin HY, Babitt JL.

Gastroenterology. 2010 Nov;139(5):1721-9. doi: 10.1053/j.gastro.2010.07.044. Epub 2010 Aug 1.

17.

Distinct requirements for Hfe in basal and induced hepcidin levels in iron overload and inflammation.

Constante M, Jiang W, Wang D, Raymond VA, Bilodeau M, Santos MM.

Am J Physiol Gastrointest Liver Physiol. 2006 Aug;291(2):G229-37. Epub 2006 Mar 24.

18.

Absorption of manganese and iron in a mouse model of hemochromatosis.

Kim J, Buckett PD, Wessling-Resnick M.

PLoS One. 2013 May 21;8(5):e64944. doi: 10.1371/journal.pone.0064944. Print 2013.

19.

Iron overload in adult Hfe-deficient mice independent of changes in the steady-state expression of the duodenal iron transporters DMT1 and Ireg1/ferroportin.

Herrmann T, Muckenthaler M, van der Hoeven F, Brennan K, Gehrke SG, Hubert N, Sergi C, Gröne HJ, Kaiser I, Gosch I, Volkmann M, Riedel HD, Hentze MW, Stewart AF, Stremmel W.

J Mol Med (Berl). 2004 Jan;82(1):39-48. Epub 2003 Nov 15.

PMID:
14618243
20.

Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.

Delima RD, Chua AC, Tirnitz-Parker JE, Gan EK, Croft KD, Graham RM, Olynyk JK, Trinder D.

Hepatology. 2012 Aug;56(2):585-93. doi: 10.1002/hep.25689. Epub 2012 Jun 11.

PMID:
22383097

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