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Identification of nuclear protein targets for six leukemogenic tyrosine kinases governed by post-translational regulation.

Pierce A, Williamson A, Jaworska E, Griffiths JR, Taylor S, Walker M, Aspinall-O'Dea M, Spooncer E, Unwin RD, Poolman T, Ray D, Whetton AD.

PLoS One. 2012;7(6):e38928. doi: 10.1371/journal.pone.0038928. Epub 2012 Jun 22. Erratum in: PLoS One. 2013;8(6). doi:10.1371/annotation/df82a4c0-2909-43a0-8a7f-5bd2ce9ca0bd. O'Dea, Mark Aspinall [corrected to Aspinall-O'Dea, Mark].


Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases.

Pierce A, Unwin RD, Evans CA, Griffiths S, Carney L, Zhang L, Jaworska E, Lee CF, Blinco D, Okoniewski MJ, Miller CJ, Bitton DA, Spooncer E, Whetton AD.

Mol Cell Proteomics. 2008 May;7(5):853-63. Epub 2007 Oct 21.


Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.

Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.

Oncogene. 2007 Aug 16;26(38):5606-14. Epub 2007 Mar 12.


Assessment of downstream effectors of BCR/ABL protein tyrosine kinase using combined proteomic approaches.

Lee CF, Griffiths S, Rodríguez-Suárez E, Pierce A, Unwin RD, Jaworska E, Evans CA, J Gaskell S, Whetton AD.

Proteomics. 2010 Sep;10(18):3321-42. doi: 10.1002/pmic.201000176.


Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway.

Chin H, Arai A, Wakao H, Kamiyama R, Miyasaka N, Miura O.

Blood. 1998 May 15;91(10):3734-45.


PTMScan direct: identification and quantification of peptides from critical signaling proteins by immunoaffinity enrichment coupled with LC-MS/MS.

Stokes MP, Farnsworth CL, Moritz A, Silva JC, Jia X, Lee KA, Guo A, Polakiewicz RD, Comb MJ.

Mol Cell Proteomics. 2012 May;11(5):187-201. doi: 10.1074/mcp.M111.015883. Epub 2012 Feb 9.


Site-specific phosphorylation dynamics of the nuclear proteome during the DNA damage response.

Bennetzen MV, Larsen DH, Bunkenborg J, Bartek J, Lukas J, Andersen JS.

Mol Cell Proteomics. 2010 Jun;9(6):1314-23. doi: 10.1074/mcp.M900616-MCP200. Epub 2010 Feb 16.


Tec protein-tyrosine kinase is involved in interleukin-3 signaling pathway.

Mano H, Yamashita Y, Sato K, Yazaki Y, Hirai H.

Blood. 1995 Jan 15;85(2):343-50.


Regulation of the trans-activation potential of STAT5 through its DNA-binding activity and interactions with heterologous transcription factors.

Groner B, Fritsche M, Stöcklin E, Berchtold S, Merkle C, Moriggl R, Pfitzner E.

Growth Horm IGF Res. 2000 Apr;10 Suppl B:S15-20. Review.


Identification and characterization of a nuclear interacting partner of anaplastic lymphoma kinase (NIPA).

Ouyang T, Bai RY, Bassermann F, von Klitzing C, Klumpen S, Miething C, Morris SW, Peschel C, Duyster J.

J Biol Chem. 2003 Aug 8;278(32):30028-36. Epub 2003 May 14.


Phosphorylation-dependent interactions between ADAM15 cytoplasmic domain and Src family protein-tyrosine kinases.

Poghosyan Z, Robbins SM, Houslay MD, Webster A, Murphy G, Edwards DR.

J Biol Chem. 2002 Feb 15;277(7):4999-5007. Epub 2001 Dec 10.


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