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Items: 1 to 20 of 135

1.

An overlapping protein-coding region in influenza A virus segment 3 modulates the host response.

Jagger BW, Wise HM, Kash JC, Walters KA, Wills NM, Xiao YL, Dunfee RL, Schwartzman LM, Ozinsky A, Bell GL, Dalton RM, Lo A, Efstathiou S, Atkins JF, Firth AE, Taubenberger JK, Digard P.

Science. 2012 Jul 13;337(6091):199-204. doi: 10.1126/science.1222213.

2.

Virology. Frameshifting to PA-X influenza.

Yewdell JW, Ince WL.

Science. 2012 Jul 13;337(6091):164-5. doi: 10.1126/science.1225539. No abstract available.

3.

The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice.

Forero A, Tisoncik-Go J, Watanabe T, Zhong G, Hatta M, Tchitchek N, Selinger C, Chang J, Barker K, Morrison J, Berndt JD, Moon RT, Josset L, Kawaoka Y, Katze MG.

J Virol. 2015 Dec 9;90(5):2240-53. doi: 10.1128/JVI.02974-15.

4.

Virulence and genetic compatibility of polymerase reassortant viruses derived from the pandemic (H1N1) 2009 influenza virus and circulating influenza A viruses.

Song MS, Pascua PN, Lee JH, Baek YH, Park KJ, Kwon HI, Park SJ, Kim CJ, Kim H, Webby RJ, Webster RG, Choi YK.

J Virol. 2011 Jul;85(13):6275-86. doi: 10.1128/JVI.02125-10.

5.

Influenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune Responses.

Hayashi T, MacDonald LA, Takimoto T.

J Virol. 2015 Jun;89(12):6442-52. doi: 10.1128/JVI.00319-15.

6.

Twenty amino acids at the C-terminus of PA-X are associated with increased influenza A virus replication and pathogenicity.

Gao H, Sun H, Hu J, Qi L, Wang J, Xiong X, Wang Y, He Q, Lin Y, Kong W, Seng LG, Pu J, Chang KC, Liu X, Liu J, Sun Y.

J Gen Virol. 2015 Aug;96(8):2036-49. doi: 10.1099/vir.0.000143.

7.

Evolutionary conservation of the PA-X open reading frame in segment 3 of influenza A virus.

Shi M, Jagger BW, Wise HM, Digard P, Holmes EC, Taubenberger JK.

J Virol. 2012 Nov;86(22):12411-3. doi: 10.1128/JVI.01677-12.

8.

An influenza reassortant with polymerase of pH1N1 and NS gene of H3N2 influenza A virus is attenuated in vivo.

Shelton H, Smith M, Hartgroves L, Stilwell P, Roberts K, Johnson B, Barclay W.

J Gen Virol. 2012 May;93(Pt 5):998-1006. doi: 10.1099/vir.0.039701-0.

9.

PA-X decreases the pathogenicity of highly pathogenic H5N1 influenza A virus in avian species by inhibiting virus replication and host response.

Hu J, Mo Y, Wang X, Gu M, Hu Z, Zhong L, Wu Q, Hao X, Hu S, Liu W, Liu H, Liu X, Liu X.

J Virol. 2015 Apr;89(8):4126-42. doi: 10.1128/JVI.02132-14.

10.

Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models.

Ma W, Lager KM, Li X, Janke BH, Mosier DA, Painter LE, Ulery ES, Ma J, Lekcharoensuk P, Webby RJ, Richt JA.

Virology. 2011 Feb 5;410(1):1-6. doi: 10.1016/j.virol.2010.10.027.

11.

The PA-gene-mediated lethal dissemination and excessive innate immune response contribute to the high virulence of H5N1 avian influenza virus in mice.

Hu J, Hu Z, Song Q, Gu M, Liu X, Wang X, Hu S, Chen C, Liu H, Liu W, Chen S, Peng D, Liu X.

J Virol. 2013 Mar;87(5):2660-72. doi: 10.1128/JVI.02891-12.

12.

Virulence of pandemic (H1N1) 2009 influenza A polymerase reassortant viruses.

Song MS, Pascua PN, Choi YK.

Virulence. 2011 Sep-Oct;2(5):422-6. doi: 10.4161/viru.2.5.17267. Review.

PMID:
21921678
13.

Molecular Determinants of Virulence and Stability of a Reporter-Expressing H5N1 Influenza A Virus.

Zhao D, Fukuyama S, Yamada S, Lopes TJ, Maemura T, Katsura H, Ozawa M, Watanabe S, Neumann G, Kawaoka Y.

J Virol. 2015 Nov;89(22):11337-46. doi: 10.1128/JVI.01886-15.

14.

The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA.

Bavagnoli L, Cucuzza S, Campanini G, Rovida F, Paolucci S, Baldanti F, Maga G.

Nucleic Acids Res. 2015 Oct 30;43(19):9405-17. doi: 10.1093/nar/gkv926.

15.

Identification of a Novel Viral Protein Expressed from the PB2 Segment of Influenza A Virus.

Yamayoshi S, Watanabe M, Goto H, Kawaoka Y.

J Virol. 2015 Oct 21;90(1):444-56. doi: 10.1128/JVI.02175-15.

16.

Analysis by single-gene reassortment demonstrates that the 1918 influenza virus is functionally compatible with a low-pathogenicity avian influenza virus in mice.

Qi L, Davis AS, Jagger BW, Schwartzman LM, Dunham EJ, Kash JC, Taubenberger JK.

J Virol. 2012 Sep;86(17):9211-20. doi: 10.1128/JVI.00887-12.

17.

Caspase-1 deficient mice are more susceptible to influenza A virus infection with PA variation.

Huang CH, Chen CJ, Yen CT, Yu CP, Huang PN, Kuo RL, Lin SJ, Chang CK, Shih SR.

J Infect Dis. 2013 Dec 1;208(11):1898-905. doi: 10.1093/infdis/jit381.

18.

Quantitative proteomic analysis of the influenza A virus nonstructural proteins NS1 and NS2 during natural cell infection identifies PACT as an NS1 target protein and antiviral host factor.

Tawaratsumida K, Phan V, Hrincius ER, High AA, Webby R, Redecke V, H├Ącker H.

J Virol. 2014 Aug;88(16):9038-48. doi: 10.1128/JVI.00830-14.

19.

Adaption of seasonal H1N1 influenza virus in mice.

Xu L, Bao L, Li F, Lv Q, Ma Y, Zhou J, Xu Y, Deng W, Zhan L, Zhu H, Ma C, Shu Y, Qin C.

PLoS One. 2011;6(12):e28901. doi: 10.1371/journal.pone.0028901.

20.

Mutations in polymerase genes enhanced the virulence of 2009 pandemic H1N1 influenza virus in mice.

Zhu W, Zhu Y, Qin K, Yu Z, Gao R, Yu H, Zhou J, Shu Y.

PLoS One. 2012;7(3):e33383. doi: 10.1371/journal.pone.0033383.

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