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Mast cells in human adipose tissue: link with morbid obesity, inflammatory status, and diabetes.

Divoux A, Moutel S, Poitou C, Lacasa D, Veyrie N, Aissat A, Arock M, Guerre-Millo M, Clément K.

J Clin Endocrinol Metab. 2012 Sep;97(9):E1677-85. doi: 10.1210/jc.2012-1532. Epub 2012 Jun 28.


Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss.

Divoux A, Tordjman J, Lacasa D, Veyrie N, Hugol D, Aissat A, Basdevant A, Guerre-Millo M, Poitou C, Zucker JD, Bedossa P, Clément K.

Diabetes. 2010 Nov;59(11):2817-25. doi: 10.2337/db10-0585. Epub 2010 Aug 16.


Association of adipose tissue and liver fibrosis with tissue stiffness in morbid obesity: links with diabetes and BMI loss after gastric bypass.

Abdennour M, Reggio S, Le Naour G, Liu Y, Poitou C, Aron-Wisnewsky J, Charlotte F, Bouillot JL, Torcivia A, Sasso M, Miette V, Zucker JD, Bedossa P, Tordjman J, Clement K.

J Clin Endocrinol Metab. 2014 Mar;99(3):898-907. doi: 10.1210/jc.2013-3253. Epub 2014 Jan 1.


Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue.

Rouault C, Pellegrinelli V, Schilch R, Cotillard A, Poitou C, Tordjman J, Sell H, Clément K, Lacasa D.

Endocrinology. 2013 Mar;154(3):1069-79. doi: 10.1210/en.2012-1415. Epub 2013 Jan 31.


Mast cells are not associated with systemic insulin resistance.

Einwallner E, Kiefer FW, Di Caro G, Orthofer M, Witzeneder N, Hörmann G, Itariu B, Zeyda M, Penninger JM, Stulnig TM, Esterbauer H, Todoric J.

Eur J Clin Invest. 2016 Nov;46(11):911-919. doi: 10.1111/eci.12675. Epub 2016 Oct 1.


Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity.

Cancello R, Tordjman J, Poitou C, Guilhem G, Bouillot JL, Hugol D, Coussieu C, Basdevant A, Bar Hen A, Bedossa P, Guerre-Millo M, Clément K.

Diabetes. 2006 Jun;55(6):1554-61.


Association between omental adipose tissue macrophages and liver histopathology in morbid obesity: influence of glycemic status.

Tordjman J, Poitou C, Hugol D, Bouillot JL, Basdevant A, Bedossa P, Guerre-Millo M, Clement K.

J Hepatol. 2009 Aug;51(2):354-62. doi: 10.1016/j.jhep.2009.02.031. Epub 2009 Apr 24.


CCL5 promotes macrophage recruitment and survival in human adipose tissue.

Keophiphath M, Rouault C, Divoux A, Clément K, Lacasa D.

Arterioscler Thromb Vasc Biol. 2010 Jan;30(1):39-45. doi: 10.1161/ATVBAHA.109.197442. Epub 2009 Nov 5.


Urokinase plasminogen activator receptor in adipose tissue macrophages of morbidly obese subjects.

Cancello R, Rouault C, Guilhem G, Bedel JF, Poitou C, Di Blasio AM, Basdevant A, Tordjman J, Clément K.

Obes Facts. 2011;4(1):17-25. doi: 10.1159/000324587. Epub 2011 Feb 16.


Visceral fat accumulation is an indicator of adipose tissue macrophage infiltration in women.

Michaud A, Drolet R, Noël S, Paris G, Tchernof A.

Metabolism. 2012 May;61(5):689-98. doi: 10.1016/j.metabol.2011.10.004. Epub 2011 Dec 7.


Inflammatory phenotyping identifies CD11d as a gene markedly induced in white adipose tissue in obese rodents and women.

Thomas AP, Dunn TN, Oort PJ, Grino M, Adams SH.

J Nutr. 2011 Jun;141(6):1172-80. doi: 10.3945/jn.110.127068. Epub 2011 Apr 20.


A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis.

Marcelin G, Ferreira A, Liu Y, Atlan M, Aron-Wisnewsky J, Pelloux V, Botbol Y, Ambrosini M, Fradet M, Rouault C, Hénégar C, Hulot JS, Poitou C, Torcivia A, Nail-Barthelemy R, Bichet JC, Gautier EL, Clément K.

Cell Metab. 2017 Mar 7;25(3):673-685. doi: 10.1016/j.cmet.2017.01.010. Epub 2017 Feb 16.


Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity.

Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, Karpe F, Humphreys S, Bedinger DH, Dunn TN, Thomas AP, Oort PJ, Kieffer DA, Amin R, Bettaieb A, Haj FG, Permana P, Anthony TG, Adams SH.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1175-87. doi: 10.1152/ajpendo.00630.2012. Epub 2013 Mar 19.


Involvement of mast cells in adipose tissue fibrosis.

Hirai S, Ohyane C, Kim YI, Lin S, Goto T, Takahashi N, Kim CS, Kang J, Yu R, Kawada T.

Am J Physiol Endocrinol Metab. 2014 Feb;306(3):E247-55. doi: 10.1152/ajpendo.00056.2013. Epub 2013 Dec 10.


Application of novel tissue microarrays to investigate expression of tryptase, chymase and KIT protein in placental mast cells.

Noack F, Krüger S, Thorns C, Finas D, Stöcker W, Diedrich K, Horny HP.

Arch Gynecol Obstet. 2005 Sep;272(3):223-8. Epub 2005 Sep 2.


Recent advances in the relationship between obesity, inflammation, and insulin resistance.

Bastard JP, Maachi M, Lagathu C, Kim MJ, Caron M, Vidal H, Capeau J, Feve B.

Eur Cytokine Netw. 2006 Mar;17(1):4-12. Review.


Expression of cytokine signaling genes in morbidly obese patients with non-alcoholic steatohepatitis and hepatic fibrosis.

Estep JM, Baranova A, Hossain N, Elariny H, Ankrah K, Afendy A, Chandhoke V, Younossi ZM.

Obes Surg. 2009 May;19(5):617-24. doi: 10.1007/s11695-009-9814-x. Epub 2009 Mar 12.


Severe obesity increases adipose tissue expression of interleukin-33 and its receptor ST2, both predominantly detectable in endothelial cells of human adipose tissue.

Zeyda M, Wernly B, Demyanets S, Kaun C, Hämmerle M, Hantusch B, Schranz M, Neuhofer A, Itariu BK, Keck M, Prager G, Wojta J, Stulnig TM.

Int J Obes (Lond). 2013 May;37(5):658-65. doi: 10.1038/ijo.2012.118. Epub 2012 Jul 17.


High levels of CRP in morbid obesity: the central role of adipose tissue and lessons for clinical practice before and after bariatric surgery.

Paepegaey AC, Genser L, Bouillot JL, Oppert JM, Clément K, Poitou C.

Surg Obes Relat Dis. 2015 Jan-Feb;11(1):148-54. doi: 10.1016/j.soard.2014.06.010. Epub 2014 Jun 18.


Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity.

Henegar C, Tordjman J, Achard V, Lacasa D, Cremer I, Guerre-Millo M, Poitou C, Basdevant A, Stich V, Viguerie N, Langin D, Bedossa P, Zucker JD, Clement K.

Genome Biol. 2008 Jan 21;9(1):R14. doi: 10.1186/gb-2008-9-1-r14.

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