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Distinct roles for extracellular signal-regulated kinase 1 (ERK1) and ERK2 in the structure and production of a primate gammaherpesvirus.

Woodson EN, Kedes DH.

J Virol. 2012 Sep;86(18):9721-36. doi: 10.1128/JVI.00695-12. Epub 2012 Jun 27.


Maturation and vesicle-mediated egress of primate gammaherpesvirus rhesus monkey rhadinovirus require inner tegument protein ORF52.

Anderson MS, Loftus MS, Kedes DH.

J Virol. 2014 Aug;88(16):9111-28. doi: 10.1128/JVI.01502-14. Epub 2014 Jun 4.


Progressive accumulation of activated ERK2 within highly stable ORF45-containing nuclear complexes promotes lytic gammaherpesvirus infection.

Woodson EN, Anderson MS, Loftus MS, Kedes DH.

PLoS Pathog. 2014 Apr 10;10(4):e1004066. doi: 10.1371/journal.ppat.1004066. eCollection 2014 Apr. Erratum in: PLoS Pathog. 2014 Apr;10(4):e1004147.


A Conserved Leucine Zipper Motif in Gammaherpesvirus ORF52 Is Critical for Distinct Microtubule Rearrangements.

Loftus MS, Verville N, Kedes DH.

J Virol. 2017 Aug 10;91(17). pii: e00304-17. doi: 10.1128/JVI.00304-17. Print 2017 Sep 1.


The Viral Bcl-2 Homologs of Kaposi's Sarcoma-Associated Herpesvirus and Rhesus Rhadinovirus Share an Essential Role for Viral Replication.

Gallo A, Lampe M, Günther T, Brune W.

J Virol. 2017 Feb 28;91(6). pii: e01875-16. doi: 10.1128/JVI.01875-16. Print 2017 Mar 15.


The rhesus rhadinovirus CD200 homologue affects immune responses and viral loads during in vivo infection.

Estep RD, Rawlings SD, Li H, Manoharan M, Blaine ET, O'Connor MA, Messaoudi I, Axthelm MK, Wong SW.

J Virol. 2014 Sep;88(18):10635-54. doi: 10.1128/JVI.01276-14. Epub 2014 Jul 2.


A Rhesus Rhadinovirus Viral Interferon (IFN) Regulatory Factor Is Virion Associated and Inhibits the Early IFN Antiviral Response.

Morin G, Robinson BA, Rogers KS, Wong SW.

J Virol. 2015 Aug;89(15):7707-21. doi: 10.1128/JVI.01175-15. Epub 2015 May 13.


Porcine reproductive and respiratory syndrome virus replication is suppressed by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway.

Lee YJ, Lee C.

Virus Res. 2010 Sep;152(1-2):50-8. doi: 10.1016/j.virusres.2010.06.002. Epub 2010 Jun 9.


Extracellular signal-regulated kinase (ERK) activation is required for porcine epidemic diarrhea virus replication.

Kim Y, Lee C.

Virology. 2015 Oct;484:181-93. doi: 10.1016/j.virol.2015.06.007. Epub 2015 Jun 23.


Rhesus monkey rhadinovirus: a model for the study of KSHV.

O'Connor CM, Kedes DH.

Curr Top Microbiol Immunol. 2007;312:43-69. Review.


Both ERK1 and ERK2 are required for enterovirus 71 (EV71) efficient replication.

Zhu M, Duan H, Gao M, Zhang H, Peng Y.

Viruses. 2015 Mar 20;7(3):1344-56. doi: 10.3390/v7031344.


Disruption of LANA in rhesus rhadinovirus generates a highly lytic recombinant virus.

Wen KW, Dittmer DP, Damania B.

J Virol. 2009 Oct;83(19):9786-802. doi: 10.1128/JVI.00704-09. Epub 2009 Jul 8.


The role of ERK2 in colorectal carcinogenesis is partly regulated by TRAPPC4.

Weng YR, Kong X, Yu YN, Wang YC, Hong J, Zhao SL, Fang JY.

Mol Carcinog. 2014 Feb;53 Suppl 1:E72-84. doi: 10.1002/mc.22031. Epub 2013 Apr 26.


Analysis of isoform specific ERK signaling on the effects of interleukin-1β on COX-2 expression and PGE2 production in human chondrocytes.

Wang X, Li F, Fan C, Wang C, Ruan H.

Biochem Biophys Res Commun. 2010 Nov 5;402(1):23-9. doi: 10.1016/j.bbrc.2010.09.095. Epub 2010 Sep 29.


Tpl2/AP-1 enhances murine gammaherpesvirus 68 lytic replication.

Li X, Feng J, Chen S, Peng L, He WW, Qi J, Deng H, Sun R.

J Virol. 2010 Feb;84(4):1881-90. doi: 10.1128/JVI.01856-09. Epub 2009 Nov 25.


Molecular characterization of the rhesus rhadinovirus (RRV) ORF4 gene and the RRV complement control protein it encodes.

Mark L, Spiller OB, Okroj M, Chanas S, Aitken JA, Wong SW, Damania B, Blom AM, Blackbourn DJ.

J Virol. 2007 Apr;81(8):4166-76. Epub 2007 Feb 7.

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