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The extent of P2Y12 inhibition by clopidogrel in diabetes mellitus patients with acute coronary syndrome is not related to glycaemic control: roles of white blood cell count and body weight.

Morel O, El Ghannudi S, Hess S, Reydel A, Crimizade U, Jesel L, Radulescu B, Wiesel ML, Gachet C, Ohlmann P.

Thromb Haemost. 2012 Aug;108(2):338-48. doi: 10.1160/TH11-12-0876. Epub 2012 Jun 28.


Impaired inhibition of P2Y(12) by clopidogrel is a major determinant of cardiac death in diabetes mellitus patients treated by percutaneous coronary intervention.

El Ghannudi S, Ohlmann P, Jesel L, Radulescu B, El Adraa E, Crimizade U, Wiesel ML, Gachet C, Morel O.

Atherosclerosis. 2011 Aug;217(2):465-72. doi: 10.1016/j.atherosclerosis.2011.03.039. Epub 2011 Apr 5.


Cardiovascular mortality in chronic kidney disease patients undergoing percutaneous coronary intervention is mainly related to impaired P2Y12 inhibition by clopidogrel.

Morel O, El Ghannudi S, Jesel L, Radulescu B, Meyer N, Wiesel ML, Caillard S, Campia U, Moulin B, Gachet C, Ohlmann P.

J Am Coll Cardiol. 2011 Jan 25;57(4):399-408. doi: 10.1016/j.jacc.2010.09.032.


Impact of P2Y12 inhibition by clopidogrel on cardiovascular mortality in unselected patients treated by percutaneous coronary angioplasty: a prospective registry.

El Ghannudi S, Ohlmann P, Meyer N, Wiesel ML, Radulescu B, Chauvin M, Bareiss P, Gachet C, Morel O.

JACC Cardiovasc Interv. 2010 Jun;3(6):648-56. doi: 10.1016/j.jcin.2010.03.003.


Platelet reactivity in diabetic patients undergoing coronary stenting for acute coronary syndrome treated with clopidogrel loading dose followed by prasugrel maintenance therapy.

Cuisset T, Gaborit B, Dubois N, Quilici J, Loosveld M, Beguin S, Loundou AD, Moro PJ, Morange PE, Alessi MC, Dutour A, Bonnet JL.

Int J Cardiol. 2013 Sep 20;168(1):523-8. doi: 10.1016/j.ijcard.2012.09.214. Epub 2012 Oct 16.


Clinical implications of very low on-treatment platelet reactivity in patients treated with thienopyridine: the POBA study (predictor of bleedings with antiplatelet drugs).

Cuisset T, Grosdidier C, Loundou AD, Quilici J, Loosveld M, Camoin L, Pankert M, Beguin S, Lambert M, Morange PE, Bonnet JL, Alessi MC.

JACC Cardiovasc Interv. 2013 Aug;6(8):854-63. doi: 10.1016/j.jcin.2013.04.009.


Comparison of platelet reactivity and periprocedural outcomes in patients with versus without diabetes mellitus and treated with clopidogrel and percutaneous coronary intervention.

Mangiacapra F, Patti G, Peace A, Gatto L, Vizzi V, Ricottini E, D'Ambrosio A, Muller O, Barbato E, Di Sciascio G.

Am J Cardiol. 2010 Sep 1;106(5):619-23. doi: 10.1016/j.amjcard.2010.04.015.


Relationship between post-treatment platelet reactivity and ischemic and bleeding events at 1-year follow-up in patients receiving prasugrel.

Bonello L, Mancini J, Pansieri M, Maillard L, Rossi P, Collet F, Jouve B, Wittenberg O, Laine M, Michelet P, Bessereau J, Lemesle G, Dignat-George F, Paganelli F, Camoin-Jau L.

J Thromb Haemost. 2012 Oct;10(10):1999-2005. doi: 10.1111/j.1538-7836.2012.04875.x.


Platelet reactivity evaluated with the VASP assay following ticagrelor loading dose in acute coronary syndrome patients undergoing percutaneous coronary intervention.

Laine M, Toesca R, Berbis J, Frere C, Barnay P, Pansieri M, Peyre JP, Michelet P, Bessereau J, Camilleri E, Helaf O, Camaleonte M, Paganelli F, Dignat-George F, Bonello L.

Thromb Res. 2013 Jul;132(1):e15-8. doi: 10.1016/j.thromres.2013.04.030. Epub 2013 May 30.


Impact of initial clinical presentation on clopidogrel low response.

Landel JB, Bauters A, Delhaye C, Bonello L, Sudre A, Susen S, Bauters C, Lablanche JM, Lemesle G.

Arch Cardiovasc Dis. 2013 Nov;106(11):593-600. doi: 10.1016/j.acvd.2013.06.050. Epub 2013 Sep 23.


[Platelet responsiveness to clopidogrel in patients with coronary syndrome. Comparison of platelet aggregation induced by ADP and flow cytometric analysis of intraplatelet VASP phosphorylation].

Morel O, Viellard C, Faure A, Jesel L, Ohlmann P, Desprez D, Chauvin M, Roul G, Grunebaum L, Bareiss P.

Ann Cardiol Angeiol (Paris). 2007 Jan;56(1):21-9. French.


Influence of platelet reactivity and response to clopidogrel on myocardial damage following percutaneous coronary intervention in patients with non-ST-segment elevation acute coronary syndrome.

Perez de Prado A, Cuellas C, Diego A, de Miguel A, Samaniego B, Alonso-Orcajo N, Carbonell R, Pascual C, Fernandez-Vazquez F, Calabozo RG.

Thromb Res. 2009 Dec;124(6):678-82. doi: 10.1016/j.thromres.2009.04.004. Epub 2009 May 2.


Platelet reactivity in patients receiving a maintenance dose of P2Y12-ADP receptor antagonists undergoing elective percutaneous coronary intervention.

Bonello L, Laine M, Thuny F, Paganelli F, Lemesle G, Roch A, Kerbaul F, Dignat-George F, Berbis J, Frere C.

Int J Cardiol. 2016 Aug 1;216:190-3. doi: 10.1016/j.ijcard.2016.04.165. Epub 2016 May 1.


Selection of P2Y12 antagonist, treatment initiation, and predictors of high on-treatment platelet reactivity in a "Real World" registry.

Motovska Z, Ondrakova M, Bednar F, Knot J, Ulman J, Maly M.

Thromb Res. 2015 Jun;135(6):1093-9. doi: 10.1016/j.thromres.2015.04.014. Epub 2015 Apr 16.


Clinical effects and outcomes with new P2Y12 inhibitors in ACS.

Collet JP, O'Connor S.

Fundam Clin Pharmacol. 2012 Feb;26(1):16-8. doi: 10.1111/j.1472-8206.2011.00984.x. Epub 2011 Sep 5. Review.


Role of the T744C polymorphism of the P2Y12 gene on platelet response to a 600-mg loading dose of clopidogrel in 597 patients with non-ST-segment elevation acute coronary syndrome.

Cuisset T, Frere C, Quilici J, Morange PE, Saut N, Lambert M, Camoin L, Vague IJ, Bonnet JL, Alessi MC.

Thromb Res. 2007;120(6):893-9. Epub 2007 Mar 6.


Biological efficacy of a 600 mg loading dose of clopidogrel in ST-elevation myocardial infarction.

Bonello L, Berbis J, Laine M, Armero S, Bessereau J, Jacquin L, Bonello C, Camillieri E, Barragan P, Dignat-George F, Paganelli F, Camoin-Jau L.

Thromb Haemost. 2012 Jul;108(1):101-6. doi: 10.1160/TH12-02-0125. Epub 2012 Apr 26.


Relationship between aspirin and clopidogrel responses in acute coronary syndrome and clinical predictors of non response.

Cuisset T, Frere C, Quilici J, Morange PE, Camoin L, Bali L, Lambert M, Juhan-Vague I, Alessi MC, Bonnet JL.

Thromb Res. 2009 Feb;123(4):597-603. doi: 10.1016/j.thromres.2008.04.003. Epub 2008 May 21.


Comparison of conventional aggregometry with VASP for monitoring P2Y12-specific platelet inhibition.

Aradi D, Magyarlaki T, Tokés-Füzesi M, Rideg O, Vorobcsuk A, Komócsi A.

Platelets. 2010;21(7):563-70. doi: 10.3109/09537104.2010.494742.


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