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Items: 1 to 20 of 88

1.

Effects of 18-kDa translocator protein knockdown on gene expression of glutamate receptors, transporters, and metabolism, and on cell viability affected by glutamate.

Veenman L, Bode J, Gaitner M, Caballero B, Peʼer Y, Zeno S, Kietz S, Kugler W, Lakomek M, Gavish M.

Pharmacogenet Genomics. 2012 Aug;22(8):606-19. doi: 10.1097/FPC.0b013e3283544531.

PMID:
22732722
2.

The 18-kDa translocator protein, formerly known as the peripheral-type benzodiazepine receptor, confers proapoptotic and antineoplastic effects in a human colorectal cancer cell line.

Shoukrun R, Veenman L, Shandalov Y, Leschiner S, Spanier I, Karry R, Katz Y, Weisinger G, Weizman A, Gavish M.

Pharmacogenet Genomics. 2008 Nov;18(11):977-88. doi: 10.1097/FPC.0b013e3283117d52.

PMID:
18806692
3.

CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells.

Zeno S, Zaaroor M, Leschiner S, Veenman L, Gavish M.

Biochemistry. 2009 Jun 2;48(21):4652-61. doi: 10.1021/bi900064t.

PMID:
19358520
4.

Classical and Novel TSPO Ligands for the Mitochondrial TSPO Can Modulate Nuclear Gene Expression: Implications for Mitochondrial Retrograde Signaling.

Yasin N, Veenman L, Singh S, Azrad M, Bode J, Vainshtein A, Caballero B, Marek I, Gavish M.

Int J Mol Sci. 2017 Apr 7;18(4). pii: E786. doi: 10.3390/ijms18040786.

5.

The 18 kDa translocator protein influences angiogenesis, as well as aggressiveness, adhesion, migration, and proliferation of glioblastoma cells.

Bode J, Veenman L, Caballero B, Lakomek M, Kugler W, Gavish M.

Pharmacogenet Genomics. 2012 Jul;22(7):538-50. doi: 10.1097/FPC.0b013e3283539cdc.

PMID:
22547081
6.

Silencing of selected glutamate receptor subunits modulates cancer growth.

Luksch H, Uckermann O, Stepulak A, Hendruschk S, Marzahn J, Bastian S, Staufner C, Temme A, Ikonomidou C.

Anticancer Res. 2011 Oct;31(10):3181-92.

PMID:
21965725
7.

Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment.

van Vuurden DG, Yazdani M, Bosma I, Broekhuizen AJ, Postma TJ, Heimans JJ, van der Valk P, Aronica E, Tannous BA, Würdinger T, Kaspers GJ, Cloos J.

PLoS One. 2009 Jun 18;4(6):e5953. doi: 10.1371/journal.pone.0005953.

8.

Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.

Savaskan NE, Seufert S, Hauke J, Tränkle C, Eyüpoglu IY, Hahnen E.

Oncogene. 2011 Jan 6;30(1):43-53. doi: 10.1038/onc.2010.391. Epub 2010 Aug 30.

PMID:
20802520
9.

Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer.

Zheng J, Boisgard R, Siquier-Pernet K, Decaudin D, Dollé F, Tavitian B.

Mol Pharm. 2011 Jun 6;8(3):823-32. doi: 10.1021/mp100433c. Epub 2011 Apr 4.

PMID:
21417480
10.

TLN-4601 peripheral benzodiazepine receptor (PBR/TSPO) binding properties do not mediate apoptosis but confer tumor-specific accumulation.

Bertomeu T, Zvereff V, Ibrahim A, Zehntner SP, Aliaga A, Rosa-Neto P, Bedell BJ, Falardeau P, Gourdeau H.

Biochem Pharmacol. 2010 Nov 15;80(10):1572-9. doi: 10.1016/j.bcp.2010.07.018. Epub 2010 Jul 22.

PMID:
20655882
11.

Inhibitory effects of 1-methyl-4-phenylpyridinium on glutamate uptake into cultured C6 glioma cells.

Yao HH, Ding JH, He HR, Hu G.

Acta Pharmacol Sin. 2004 Jul;25(7):855-60.

12.

The 18 kDa mitochondrial translocator protein (TSPO) prevents accumulation of protoporphyrin IX. Involvement of reactive oxygen species (ROS).

Zeno S, Veenman L, Katz Y, Bode J, Gavish M, Zaaroor M.

Curr Mol Med. 2012 May;12(4):494-501.

PMID:
22376065
13.

Cytotoxic effect of hemin in colonic epithelial cell line: involvement of 18 kDa translocator protein (TSPO).

Gemelli C, Dongmo BM, Ferrarini F, Grande A, Corsi L.

Life Sci. 2014 Jun 27;107(1-2):14-20. doi: 10.1016/j.lfs.2014.04.026. Epub 2014 May 2.

PMID:
24792517
14.

Role of translocator protein in melanoma growth and progression.

Ruksha T, Aksenenko M, Papadopoulos V.

Arch Dermatol Res. 2012 Dec;304(10):839-45. doi: 10.1007/s00403-012-1294-5. Epub 2012 Oct 19.

PMID:
23080515
15.

The translocator protein radioligand 18F-DPA-714 monitors antitumor effect of erufosine in a rat 9L intracranial glioma model.

Awde AR, Boisgard R, Thézé B, Dubois A, Zheng J, Dollé F, Jacobs AH, Tavitian B, Winkeler A.

J Nucl Med. 2013 Dec;54(12):2125-31. doi: 10.2967/jnumed.112.118794. Epub 2013 Nov 8.

17.

Synaptically-silent immature neurons show gaba and glutamate receptor-mediated currents in adult rat dentate gyrus.

Ambrogini P, Minelli A, Lattanzi D, Ciuffoli S, Fanelli M, Cuppini R.

Arch Ital Biol. 2006 May;144(2):115-26.

PMID:
16642790
18.

Structural requirements to obtain highly potent and selective 18 kDa Translocator Protein (TSPO) Ligands.

Taliani S, Pugliesi I, Da Settimo F.

Curr Top Med Chem. 2011;11(7):860-86. Review.

PMID:
21291396
19.

Structural and functional evolution of the translocator protein (18 kDa).

Fan J, Lindemann P, Feuilloley MG, Papadopoulos V.

Curr Mol Med. 2012 May;12(4):369-86. Review.

PMID:
22364126
20.

TSPO as a target for glioblastoma therapeutics.

Werry EL, Barron ML, Kassiou M.

Biochem Soc Trans. 2015 Aug;43(4):531-6. doi: 10.1042/BST20150015. Epub 2015 Aug 3. Review.

PMID:
26551689

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