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Items: 1 to 20 of 181

1.

Hypercapnic acidosis attenuates ventilation-induced lung injury by a nuclear factor-κB-dependent mechanism.

Contreras M, Ansari B, Curley G, Higgins BD, Hassett P, O'Toole D, Laffey JG.

Crit Care Med. 2012 Sep;40(9):2622-30. doi: 10.1097/CCM.0b013e318258f8b4.

PMID:
22732277
2.

Comparison of the effects of moderate and severe hypercapnic acidosis on ventilation-induced lung injury.

Yang W, Yue Z, Cui X, Guo Y, Zhang L, Zhou H, Li W.

BMC Anesthesiol. 2015 Apr 30;15:67. doi: 10.1186/s12871-015-0050-8.

3.

Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis.

Costello J, Higgins B, Contreras M, Chonghaile MN, Hassett P, O'Toole D, Laffey JG.

Crit Care Med. 2009 Aug;37(8):2412-20. doi: 10.1097/CCM.0b013e3181a385d3.

PMID:
19531945
4.

Hypercapnic acidosis attenuates severe acute bacterial pneumonia-induced lung injury by a neutrophil-independent mechanism.

Ni Chonghaile M, Higgins BD, Costello JF, Laffey JG.

Crit Care Med. 2008 Dec;36(12):3135-44. doi: 10.1097/CCM.0b013e31818f0d13.

PMID:
18936707
5.

Hypercapnic acidosis attenuates endotoxin-induced acute lung injury.

Laffey JG, Honan D, Hopkins N, Hyvelin JM, Boylan JF, McLoughlin P.

Am J Respir Crit Care Med. 2004 Jan 1;169(1):46-56. Epub 2003 Sep 4.

PMID:
12958048
6.

Effects and Mechanisms by Which Hypercapnic Acidosis Inhibits Sepsis-Induced Canonical Nuclear Factor-κB Signaling in the Lung.

Masterson C, O'Toole D, Leo A, McHale P, Horie S, Devaney J, Laffey JG.

Crit Care Med. 2016 Apr;44(4):e207-17. doi: 10.1097/CCM.0000000000001376.

PMID:
26584194
7.

Hypercapnic acidosis attenuates reperfusion injury in isolated and perfused rat lungs.

Wu SY, Wu CP, Kang BH, Li MH, Chu SJ, Huang KL.

Crit Care Med. 2012 Feb;40(2):553-9. doi: 10.1097/CCM.0b013e318232d776.

PMID:
21946657
8.

Hypercapnic acidosis does not modulate the severity of bacterial pneumonia-induced lung injury.

O'Croinin DF, Hopkins NO, Moore MM, Boylan JF, McLoughlin P, Laffey JG.

Crit Care Med. 2005 Nov;33(11):2606-12.

PMID:
16276187
9.

Infection-induced lung injury is worsened after renal buffering of hypercapnic acidosis.

Nichol AD, O'Cronin DF, Howell K, Naughton F, O'Brien S, Boylan J, O'Connor C, O'Toole D, Laffey JG, McLoughlin P.

Crit Care Med. 2009 Nov;37(11):2953-61. doi: 10.1097/CCM.0b013e3181b028ce.

PMID:
19773647
10.

Hypercapnic acidosis attenuates lung injury induced by established bacterial pneumonia.

Chonghaile MN, Higgins BD, Costello J, Laffey JG.

Anesthesiology. 2008 Nov;109(5):837-48. doi: 10.1097/ALN.0b013e3181895fb7. Erratum in: Anesthesiology. 2009 Mar;110(3):689.

PMID:
18946296
11.

Differential effects of buffered hypercapnia versus hypercapnic acidosis on shock and lung injury induced by systemic sepsis.

Higgins BD, Costello J, Contreras M, Hassett P, O' Toole D, Laffey JG.

Anesthesiology. 2009 Dec;111(6):1317-26. doi: 10.1097/ALN.0b013e3181ba3c11.

PMID:
19934878
12.

Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappaB dependent mechanism.

O'Toole D, Hassett P, Contreras M, Higgins BD, McKeown ST, McAuley DF, O'Brien T, Laffey JG.

Thorax. 2009 Nov;64(11):976-82. doi: 10.1136/thx.2008.110304. Epub 2009 Jul 16.

PMID:
19617214
13.

Hypercapnic acidosis reduces oxidative reactions in endotoxin-induced lung injury.

Nichol AD, O'Cronin DF, Naughton F, Hopkins N, Boylan J, McLoughlin P.

Anesthesiology. 2010 Jul;113(1):116-25. doi: 10.1097/ALN.0b013e3181dfd2fe.

PMID:
20526182
14.

Sustained hypercapnic acidosis during pulmonary infection increases bacterial load and worsens lung injury.

O'Croinin DF, Nichol AD, Hopkins N, Boylan J, O'Brien S, O'Connor C, Laffey JG, McLoughlin P.

Crit Care Med. 2008 Jul;36(7):2128-35. doi: 10.1097/CCM.0b013e31817d1b59.

PMID:
18552698
15.

Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-κB pathway.

Horie S, Ansari B, Masterson C, Devaney J, Scully M, O'Toole D, Laffey JG.

Intensive Care Med Exp. 2016 Dec;4(1):8. doi: 10.1186/s40635-016-0081-6. Epub 2016 Mar 22.

16.

Hypercapnic acidosis confers antioxidant and anti-apoptosis effects against ventilator-induced lung injury.

Yang WC, Song CY, Wang N, Zhang LL, Yue ZY, Cui XG, Zhou HC.

Lab Invest. 2013 Dec;93(12):1339-49. doi: 10.1038/labinvest.2013.118. Epub 2013 Oct 14.

17.

Hypercapnic acidosis in ventilator-induced lung injury.

Peltekova V, Engelberts D, Otulakowski G, Uematsu S, Post M, Kavanagh BP.

Intensive Care Med. 2010 May;36(5):869-78. doi: 10.1007/s00134-010-1787-7. Epub 2010 Mar 6.

PMID:
20213072
18.

Hypercapnic acidosis attenuates endotoxin-induced nuclear factor-[kappa]B activation.

Takeshita K, Suzuki Y, Nishio K, Takeuchi O, Toda K, Kudo H, Miyao N, Ishii M, Sato N, Naoki K, Aoki T, Suzuki K, Hiraoka R, Yamaguchi K.

Am J Respir Cell Mol Biol. 2003 Jul;29(1):124-32. Epub 2003 Feb 6.

PMID:
12600832
19.

Effects of cyclic opening and closing at low- and high-volume ventilation on bronchoalveolar lavage cytokines.

Chu EK, Whitehead T, Slutsky AS.

Crit Care Med. 2004 Jan;32(1):168-74.

PMID:
14707576
20.

BML-111, a lipoxin receptor agonist, attenuates ventilator-induced lung injury in rats.

Li H, Wu Z, Feng D, Gong J, Yao C, Wang Y, Yuan S, Yao S, Shang Y.

Shock. 2014 Apr;41(4):311-6. doi: 10.1097/SHK.0000000000000104.

PMID:
24365886

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