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Items: 1 to 20 of 146

1.

Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum.

Neelamegan D, Schoenhofen IC, Richards JC, Cox AD.

BMC Microbiol. 2012 Jun 25;12:124. doi: 10.1186/1471-2180-12-124.

2.

Molecular identification of a functional homologue of the mammalian fatty acid amide hydrolase in Arabidopsis thaliana.

Shrestha R, Dixon RA, Chapman KD.

J Biol Chem. 2003 Sep 12;278(37):34990-7. Epub 2003 Jun 24.

3.

Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase.

Karbarz MJ, Luo L, Chang L, Tham CS, Palmer JA, Wilson SJ, Wennerholm ML, Brown SM, Scott BP, Apodaca RL, Keith JM, Wu J, Breitenbucher JG, Chaplan SR, Webb M.

Anesth Analg. 2009 Jan;108(1):316-29. doi: 10.1213/ane.0b013e31818c7cbd.

PMID:
19095868
4.

Keys to Lipid Selection in Fatty Acid Amide Hydrolase Catalysis: Structural Flexibility, Gating Residues and Multiple Binding Pockets.

Palermo G, Bauer I, Campomanes P, Cavalli A, Armirotti A, Girotto S, Rothlisberger U, De Vivo M.

PLoS Comput Biol. 2015 Jun 25;11(6):e1004231. doi: 10.1371/journal.pcbi.1004231. eCollection 2015 Jun.

5.

Assay of FAAH Activity.

Bari M, Feole M, Maccarrone M.

Methods Mol Biol. 2016;1412:131-6. doi: 10.1007/978-1-4939-3539-0_14.

PMID:
27245899
6.

Anandamide externally added to lipid vesicles containing trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion.

Kaczocha M, Lin Q, Nelson LD, McKinney MK, Cravatt BF, London E, Deutsch DG.

ACS Chem Neurosci. 2012 May 16;3(5):364-8. doi: 10.1021/cn300001w. Epub 2012 Jan 18.

7.

Role of FAAH-like anandamide transporter in anandamide inactivation.

Leung K, Elmes MW, Glaser ST, Deutsch DG, Kaczocha M.

PLoS One. 2013 Nov 4;8(11):e79355. doi: 10.1371/journal.pone.0079355. eCollection 2013.

8.

The fatty acid amide hydrolase (FAAH).

Deutsch DG, Ueda N, Yamamoto S.

Prostaglandins Leukot Essent Fatty Acids. 2002 Feb-Mar;66(2-3):201-10. Review. Erratum in: Prostaglandins Leukot Essent Fatty Acids.2003 Jan;68(1):69..

PMID:
12052036
9.

A catalytically silent FAAH-1 variant drives anandamide transport in neurons.

Fu J, Bottegoni G, Sasso O, Bertorelli R, Rocchia W, Masetti M, Guijarro A, Lodola A, Armirotti A, Garau G, Bandiera T, Reggiani A, Mor M, Cavalli A, Piomelli D.

Nat Neurosci. 2011 Nov 20;15(1):64-9. doi: 10.1038/nn.2986. Erratum in: Nat Neurosci. 2013 Dec;16(12):1907.

10.

Computational insights into function and inhibition of fatty acid amide hydrolase.

Palermo G, Rothlisberger U, Cavalli A, De Vivo M.

Eur J Med Chem. 2015 Feb 16;91:15-26. doi: 10.1016/j.ejmech.2014.09.037. Epub 2014 Sep 16. Review.

PMID:
25240419
11.

Involvement of fatty acid amide hydrolase and fatty acid binding protein 5 in the uptake of anandamide by cell lines with different levels of fatty acid amide hydrolase expression: a pharmacological study.

Björklund E, Blomqvist A, Hedlin J, Persson E, Fowler CJ.

PLoS One. 2014 Jul 31;9(7):e103479. doi: 10.1371/journal.pone.0103479. eCollection 2014.

12.

Endocannabinoid hydrolases.

Ueda N.

Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:521-34. Review.

PMID:
12432941
13.

Identification of N-acylethanolamines in Dictyostelium discoideum and confirmation of their hydrolysis by fatty acid amide hydrolase.

Hayes AC, Stupak J, Li J, Cox AD.

J Lipid Res. 2013 Feb;54(2):457-66. doi: 10.1194/jlr.M032219. Epub 2012 Nov 27.

14.

Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.

Kaczocha M, Glaser ST, Chae J, Brown DA, Deutsch DG.

J Biol Chem. 2010 Jan 22;285(4):2796-806. doi: 10.1074/jbc.M109.058461. Epub 2009 Nov 19.

15.

A second fatty acid amide hydrolase with variable distribution among placental mammals.

Wei BQ, Mikkelsen TS, McKinney MK, Lander ES, Cravatt BF.

J Biol Chem. 2006 Dec 1;281(48):36569-78. Epub 2006 Oct 2.

16.

Involvement of N-acylethanolamine-hydrolyzing acid amidase in the degradation of anandamide and other N-acylethanolamines in macrophages.

Sun YX, Tsuboi K, Zhao LY, Okamoto Y, Lambert DM, Ueda N.

Biochim Biophys Acta. 2005 Oct 1;1736(3):211-20. Epub 2005 Aug 29.

PMID:
16154384
17.

Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation.

Schlosburg JE, Kinsey SG, Lichtman AH.

AAPS J. 2009 Mar;11(1):39-44. doi: 10.1208/s12248-008-9075-y. Epub 2009 Jan 29. Review.

18.

Role for fatty acid amide hydrolase (FAAH) in the leptin-mediated effects on feeding and energy balance.

Balsevich G, Sticht M, Bowles NP, Singh A, Lee TTY, Li Z, Chelikani PK, Lee FS, Borgland SL, Hillard CJ, McEwen BS, Hill MN.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7605-7610. doi: 10.1073/pnas.1802251115. Epub 2018 Jul 2.

19.

Anandamide transport is independent of fatty-acid amide hydrolase activity and is blocked by the hydrolysis-resistant inhibitor AM1172.

Fegley D, Kathuria S, Mercier R, Li C, Goutopoulos A, Makriyannis A, Piomelli D.

Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8756-61. Epub 2004 May 11.

20.

Phenotypic assessment of THC discriminative stimulus properties in fatty acid amide hydrolase knockout and wildtype mice.

Walentiny DM, Vann RE, Wiley JL.

Neuropharmacology. 2015 Jun;93:237-42. doi: 10.1016/j.neuropharm.2015.02.004. Epub 2015 Feb 16.

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