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Items: 1 to 20 of 89

1.

p53 opens the mitochondrial permeability transition pore to trigger necrosis.

Vaseva AV, Marchenko ND, Ji K, Tsirka SE, Holzmann S, Moll UM.

Cell. 2012 Jun 22;149(7):1536-48. doi: 10.1016/j.cell.2012.05.014.

2.

A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems.

Lebedev I, Nemajerova A, Foda ZH, Kornaj M, Tong M, Moll UM, Seeliger MA.

J Mol Biol. 2016 Oct 9;428(20):4154-4167. doi: 10.1016/j.jmb.2016.08.001. Epub 2016 Aug 8.

PMID:
27515399
3.

Cysteine 203 of cyclophilin D is critical for cyclophilin D activation of the mitochondrial permeability transition pore.

Nguyen TT, Stevens MV, Kohr M, Steenbergen C, Sack MN, Murphy E.

J Biol Chem. 2011 Nov 18;286(46):40184-92. doi: 10.1074/jbc.M111.243469. Epub 2011 Sep 19.

4.

P53 dependent mitochondrial permeability transition pore opening is required for dexamethasone-induced death of osteoblasts.

Zhen YF, Wang GD, Zhu LQ, Tan SP, Zhang FY, Zhou XZ, Wang XD.

J Cell Physiol. 2014 Oct;229(10):1475-83. doi: 10.1002/jcp.24589.

PMID:
24615518
5.

Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.

Schinzel AC, Takeuchi O, Huang Z, Fisher JK, Zhou Z, Rubens J, Hetz C, Danial NN, Moskowitz MA, Korsmeyer SJ.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12005-10. Epub 2005 Aug 15.

6.

Cyclophilin D gene ablation protects mice from ischemic renal injury.

Devalaraja-Narashimha K, Diener AM, Padanilam BJ.

Am J Physiol Renal Physiol. 2009 Sep;297(3):F749-59. doi: 10.1152/ajprenal.00239.2009. Epub 2009 Jun 24.

7.

Mitochondrial permeability transition in cardiac ischemia-reperfusion: whether cyclophilin D is a viable target for cardioprotection?

Javadov S, Jang S, Parodi-Rullán R, Khuchua Z, Kuznetsov AV.

Cell Mol Life Sci. 2017 Aug;74(15):2795-2813. doi: 10.1007/s00018-017-2502-4. Epub 2017 Apr 4. Review.

PMID:
28378042
8.

Regulation of necrotic cell death: p53, PARP1 and cyclophilin D-overlapping pathways of regulated necrosis?

Ying Y, Padanilam BJ.

Cell Mol Life Sci. 2016 Jun;73(11-12):2309-24. doi: 10.1007/s00018-016-2202-5. Epub 2016 Apr 5. Review.

9.

HAX-1 regulates cyclophilin-D levels and mitochondria permeability transition pore in the heart.

Lam CK, Zhao W, Liu GS, Cai WF, Gardner G, Adly G, Kranias EG.

Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6466-75. doi: 10.1073/pnas.1508760112. Epub 2015 Nov 9.

10.

Involvement of Cyclophilin D and Calcium in Isoflurane-induced Preconditioning.

Teixeira G, Chiari P, Fauconnier J, Abrial M, Couture-Lepetit E, Harisseh R, Pillot B, Lacampagne A, Tourneur Y, Gharib A, Ovize M.

Anesthesiology. 2015 Dec;123(6):1374-84. doi: 10.1097/ALN.0000000000000876.

PMID:
26460965
11.

Inhibition of myocardial reperfusion injury by ischemic postconditioning requires sirtuin 3-mediated deacetylation of cyclophilin D.

Bochaton T, Crola-Da-Silva C, Pillot B, Villedieu C, Ferreras L, Alam MR, Thibault H, Strina M, Gharib A, Ovize M, Baetz D.

J Mol Cell Cardiol. 2015 Jul;84:61-9. doi: 10.1016/j.yjmcc.2015.03.017. Epub 2015 Apr 11.

PMID:
25871830
12.

Oxygen glucose deprivation (OGD)/re-oxygenation-induced in vitro neuronal cell death involves mitochondrial cyclophilin-D/P53 signaling axis.

Zhao LP, Ji C, Lu PH, Li C, Xu B, Gao H.

Neurochem Res. 2013 Apr;38(4):705-13. doi: 10.1007/s11064-013-0968-5. Epub 2013 Jan 16.

PMID:
23322110
13.

Modelling the molecular mechanism of protein-protein interactions and their inhibition: CypD-p53 case study.

Fayaz SM, Rajanikant GK.

Mol Divers. 2015 Nov;19(4):931-43. doi: 10.1007/s11030-015-9612-4. Epub 2015 Jul 14.

PMID:
26170095
14.

Cyclophilin D and myocardial ischemia-reperfusion injury: a fresh perspective.

Alam MR, Baetz D, Ovize M.

J Mol Cell Cardiol. 2015 Jan;78:80-9. doi: 10.1016/j.yjmcc.2014.09.026. Epub 2014 Oct 2. Review.

PMID:
25281838
15.

Cyclosporine A normalizes mitochondrial coupling, reactive oxygen species production, and inflammation and partially restores skeletal muscle maximal oxidative capacity in experimental aortic cross-clamping.

Pottecher J, Guillot M, Belaidi E, Charles AL, Lejay A, Gharib A, Diemunsch P, Geny B.

J Vasc Surg. 2013 Apr;57(4):1100-1108.e2. doi: 10.1016/j.jvs.2012.09.020. Epub 2013 Jan 18.

16.

Synergistic protective effect of cyclosporin A and rotenone against hypoxia-reoxygenation in cardiomyocytes.

Teixeira G, Abrial M, Portier K, Chiari P, Couture-Lepetit E, Tourneur Y, Ovize M, Gharib A.

J Mol Cell Cardiol. 2013 Mar;56:55-62. doi: 10.1016/j.yjmcc.2012.11.023. Epub 2012 Dec 10.

PMID:
23238221
17.
18.

Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy.

López-Erauskin J, Galino J, Bianchi P, Fourcade S, Andreu AL, Ferrer I, Muñoz-Pinedo C, Pujol A.

Brain. 2012 Dec;135(Pt 12):3584-98. doi: 10.1093/brain/aws292.

19.

DAPK1-p53 interaction converges necrotic and apoptotic pathways of ischemic neuronal death.

Pei L, Shang Y, Jin H, Wang S, Wei N, Yan H, Wu Y, Yao C, Wang X, Zhu LQ, Lu Y.

J Neurosci. 2014 May 7;34(19):6546-56. doi: 10.1523/JNEUROSCI.5119-13.2014.

20.

Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore.

Elrod JW, Molkentin JD.

Circ J. 2013;77(5):1111-22. Epub 2013 Mar 29. Review.

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