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The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.

Love IM, Sekaric P, Shi D, Grossman SR, Androphy EJ.

Cell Cycle. 2012 Jul 1;11(13):2458-66. doi: 10.4161/cc.20864. Epub 2012 Jul 1.


MDM2 inhibits PCAF (p300/CREB-binding protein-associated factor)-mediated p53 acetylation.

Jin Y, Zeng SX, Dai MS, Yang XJ, Lu H.

J Biol Chem. 2002 Aug 23;277(34):30838-43. Epub 2002 Jun 14.


Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).

Zhao Y, Lu S, Wu L, Chai G, Wang H, Chen Y, Sun J, Yu Y, Zhou W, Zheng Q, Wu M, Otterson GA, Zhu WG.

Mol Cell Biol. 2006 Apr;26(7):2782-90.


HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage.

Di Stefano V, Soddu S, Sacchi A, D'Orazi G.

Oncogene. 2005 Aug 18;24(35):5431-42.


The kinetics of p53-binding and histone acetylation at target promoters do not strictly correlate with gene expression after UV damage.

Magrini R, Russo D, Fronza G, Inga A, Menichini P.

J Cell Biochem. 2007 Apr 1;100(5):1276-87.


Intrinsic ubiquitination activity of PCAF controls the stability of the oncoprotein Hdm2.

Linares LK, Kiernan R, Triboulet R, Chable-Bessia C, Latreille D, Cuvier O, Lacroix M, Le Cam L, Coux O, Benkirane M.

Nat Cell Biol. 2007 Mar;9(3):331-8. Epub 2007 Feb 11.


Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.

Jin Q, Yu LR, Wang L, Zhang Z, Kasper LH, Lee JE, Wang C, Brindle PK, Dent SY, Ge K.

EMBO J. 2011 Jan 19;30(2):249-62. doi: 10.1038/emboj.2010.318. Epub 2010 Dec 3.


Involvement of p300/CBP and epigenetic histone acetylation in TGF-β1-mediated gene transcription in mesangial cells.

Yuan H, Reddy MA, Sun G, Lanting L, Wang M, Kato M, Natarajan R.

Am J Physiol Renal Physiol. 2013 Mar 1;304(5):F601-13. doi: 10.1152/ajprenal.00523.2012. Epub 2012 Dec 12.


SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity.

Mizuguchi Y, Specht S, Lunz JG 3rd, Isse K, Corbitt N, Takizawa T, Demetris AJ.

BMC Mol Biol. 2012 Jun 25;13:20. doi: 10.1186/1471-2199-13-20.


Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1.

Wright DG, Marchal C, Hoang K, Ankney JA, Nguyen ST, Rushing AW, Polakowski N, Miotto B, Lemasson I.

Oncotarget. 2016 Jan 12;7(2):1687-706. doi: 10.18632/oncotarget.6424.


p53-dependent growth arrest and induction of p21: a critical role for PCAF-mediated histone acetylation.

Eckner R.

Cell Cycle. 2012 Jul 15;11(14):2591-2. doi: 10.4161/cc.21235. Epub 2012 Jul 15. No abstract available.


Regulation of insulin gene transcription by multiple histone acetyltransferases.

Sampley ML, Ozcan S.

DNA Cell Biol. 2012 Jan;31(1):8-14. doi: 10.1089/dna.2011.1336. Epub 2011 Jul 20.


PCAF is an HIF-1alpha cofactor that regulates p53 transcriptional activity in hypoxia.

Xenaki G, Ontikatze T, Rajendran R, Stratford IJ, Dive C, Krstic-Demonacos M, Demonacos C.

Oncogene. 2008 Oct 2;27(44):5785-96. doi: 10.1038/onc.2008.192. Epub 2008 Jun 23.


Trichostatin A causes p53 to switch oxidative-damaged colorectal cancer cells from cell cycle arrest into apoptosis.

Habold C, Poehlmann A, Bajbouj K, Hartig R, Korkmaz KS, Roessner A, Schneider-Stock R.

J Cell Mol Med. 2008 Apr;12(2):607-21. doi: 10.1111/j.1582-4934.2007.00136.x. Erratum in: J Cell Mol Med. 2008 Aug;12(4):1421.


CDK8 is a stimulus-specific positive coregulator of p53 target genes.

Donner AJ, Szostek S, Hoover JM, Espinosa JM.

Mol Cell. 2007 Jul 6;27(1):121-33.


H3K9 histone methyltransferase G9a-mediated transcriptional activation of p21.

Oh ST, Kim KB, Chae YC, Kang JY, Hahn Y, Seo SB.

FEBS Lett. 2014 Mar 3;588(5):685-91. doi: 10.1016/j.febslet.2014.01.039. Epub 2014 Feb 1.

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